1) Ethanolysis of N-substituted norbornane epoxyimides: Discovery of diverse pathways depending on substituent's character (Organic & Biomolecular Chemistry) Tuesday March 9th 2010 2) A comparative study of the self-immolation of para-aminobenzylalcohol and hemithioaminal-based linkers in the context of protease-sensitive fluorogenic probes (Organic & Biomolecular Chemistry) Monday March 8th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 3) Synthesis of a chiral artificial receptor with catalytic activity in Michael additions and its chiral resolution by a new methodology (Organic & Biomolecular Chemistry) Monday March 8th 2010 4) Structure elucidation and spectroscopic analysis of photodegradants of the anti-rhinitis drug fluticasone furoate (Organic & Biomolecular Chemistry) Friday March 5th 2010 5) Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5[prime or minute]-monophosphates bearing a biodegradable protecting group (Organic & Biomolecular Chemistry) Friday March 5th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 6) Nucleophilicities and Lewis basicities of imidazoles, benzimidazoles, and benzotriazoles (Organic & Biomolecular Chemistry) Friday March 5th 2010 7) Solid phase synthesis of hydrogen bond surrogate derived [small alpha]-helices: resolving the case of a difficult amide coupling (Organic & Biomolecular Chemistry) Friday March 5th 2010 8) Versatile microwave-induced reactions for the multiple functionalization of carbon nanotubes (Organic & Biomolecular Chemistry) Friday March 5th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 9) Invader LNA: Efficient targeting of short double stranded DNA (Organic & Biomolecular Chemistry) Friday March 5th 2010 10) Structure elucidation of hypocreolide A by enantioselective total synthesis (Organic & Biomolecular Chemistry) Thursday March 4th 2010 11) Chemical synthesis of mouse pro-opiomelanocortin(1-74) by azido-protected glycopeptide ligation via the thioester method (Organic & Biomolecular Chemistry) Wednesday March 3rd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 12) Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions (Organic & Biomolecular Chemistry) Wednesday March 3rd 2010 13) Intracellular imaging of organelles with new water-soluble benzophenoxazine dyes (Organic & Biomolecular Chemistry) Wednesday March 3rd 2010 14) [small omega]-Transaminases as efficient biocatalysts to obtain novel chiral selenium-amine ligands for Pd-catalysis (Organic & Biomolecular Chemistry) Wednesday March 3rd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 15) A flexible approach for the asymmetric syntheses of hyacinthacines A2, A3 and structural confirmation of hyacinthacine A3 (Organic & Biomolecular Chemistry) Wednesday March 3rd 2010 16) Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols (Organic & Biomolecular Chemistry) Wednesday March 3rd 2010 17) Heck reaction on protected 3-alkyl-1,2-dien-1-ols: an approach to substituted 3-alkenylindoles, 2-alkoxy-3-alkylidene-2,3-dihydrobenzofuranes and -indolidines (Organic & Biomolecular Chemistry) Tuesday March 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 18) Assessing the superelectrophilic dimension through [sigma]-complexation, SNAr and Diels-Alder reactivity (Organic & Biomolecular Chemistry) Tuesday March 2nd 2010 19) A thermodynamic study of selective solvation in solvent mixtures (Organic & Biomolecular Chemistry) Tuesday March 2nd 2010 20) Pattern-based sensing of sulfated glycosaminoglycans with a dynamic mixture of iron complexes (Organic & Biomolecular Chemistry) Tuesday March 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 21) Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK) (Organic & Biomolecular Chemistry) Monday March 1st 2010 22) Microwave-induced electrostatic etching: generation of highly reactive magnesium for application in Grignard reagent formation (Organic & Biomolecular Chemistry) Monday March 1st 2010 23) Rhodium catalysed chemo- and stereoselective arylative and alkenylative cyclisation reactions of unsymmetric diynes containing a terminal alkyne moiety with organoboronic acids (Organic & Biomolecular Chemistry) Monday March 1st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 24) Novel polycarboxylated EDTA-type cyclodextrins as ligands for lanthanide binding: study of their luminescence, relaxivity properties of Gd(iii) complexes, and PM3 theoretical calculations (Organic & Biomolecular Chemistry) Friday February 26th 2010 25) Synthesis of the structure proposed for the natural allenic antibiotic scorodonin (Organic & Biomolecular Chemistry) Friday February 26th 2010 26) Proteasome selectivity towards Michael acceptor containing oligopeptide-based inhibitors (Organic & Biomolecular Chemistry) Thursday February 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 27) Enantiopure 2,6-disubstituted piperidines bearing one alkene- or alkyne-containing substituent: preparation and application to total syntheses of indolizidine-alkaloids (Organic & Biomolecular Chemistry) Thursday February 25th 2010 28) Streptococcus pneumoniae endohexosaminidase D; feasibility of using N-glycan oxazoline donors for synthetic glycosylation of a GlcNAc-asparagine acceptor (Organic & Biomolecular Chemistry) Thursday February 25th 2010 29) Synthesis of spirocyclic carbazole- and acridine-lactams (Organic & Biomolecular Chemistry) Thursday February 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 3 Up Votes 0 comments, related, 1 Up Vote 30) Electron transfer from aromatic amino acids to guanine and adenine radical cations in [small pi] stacked and T-shaped complexes (Organic & Biomolecular Chemistry) Thursday February 25th 2010 31) Comparative studies on lectin-carbohydrate interactions in low and high density homo- and heteroglycoclusters (Organic & Biomolecular Chemistry) Wednesday February 24th 2010 32) Oligoproline helices as structurally defined scaffolds for oligomeric G protein-coupled receptor ligands (Organic & Biomolecular Chemistry) Monday February 22nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 33) Rhodium-catalyzed [2+2+2] cycloaddition of various fluorine-containing alkynes-novel synthesis of multi-substituted fluoroalkylated aromatic compounds (Organic & Biomolecular Chemistry) Monday February 22nd 2010 34) Syntheses, structures, modification, and optical properties of meso-tetraaryl-2,3-dimethoxychlorin, and two isomeric meso-tetraaryl-2,3,12,13-tetrahydroxybacteriochlorins (Organic & Biomolecular Chemistry) Monday February 22nd 2010 35) Novel nucleobase-simplified cyclic ADP-ribose analogue: A concise synthesis and Ca2+-mobilizing activity in T-lymphocytes (Organic & Biomolecular Chemistry) Thursday February 18th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 36) Peptide and protein thioester synthesis via N[rightward arrow]S acyl transfer (Organic & Biomolecular Chemistry) Thursday February 18th 2010 37) Phosphine-free chiral metal catalysts for highly effective asymmetric catalytic hydrogenation (Organic & Biomolecular Chemistry) Thursday February 18th 2010 38) Synthesis of the first spacer containing prodrug of a duocarmycin analogue and determination of its biological activity (Organic & Biomolecular Chemistry) Wednesday February 17th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 39) Photoreversible DNA end capping for the formation of hairpin structures (Organic & Biomolecular Chemistry) Wednesday February 17th 2010 40) The application of flow microreactors to the preparation of a family of casein kinase I inhibitors (Organic & Biomolecular Chemistry) Wednesday February 17th 2010 41) Toxicity of cucurbit[7]uril and cucurbit[8]uril: an exploratory in vitro and in vivo study (Organic & Biomolecular Chemistry) Wednesday February 17th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 42) Mechanism-based crosslinking as a gauge for functional interaction of modular synthases (Organic & Biomolecular Chemistry) Wednesday February 17th 2010 43) Cyclization kinetics and biological evaluation of an anticancer 1,2-dialkynylimidazole (Organic & Biomolecular Chemistry) Monday February 15th 2010 44) Antimicrobially active cycloundecapeptides related to gramicidin S having a novel turn structure with cisd-Phe-Pro peptide bond (Organic & Biomolecular Chemistry) Monday February 15th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 45) Nitroreductase from Salmonella typhimurium: characterization and catalytic activity (Organic & Biomolecular Chemistry) Monday February 15th 2010 46) Design and synthesis of new amino-modified iminocyclitols: selective inhibitors of [small alpha]-galactosidase (Organic & Biomolecular Chemistry) Monday February 15th 2010 47) Synthesis of NH006-a photostable fungicide effective against Botrytis cinerea-according to the asymmetric total synthesis of MK8383 (Organic & Biomolecular Chemistry) Monday February 15th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 2 Up Votes 48) Cell adhesion through clustered ligand on fluid supported lipid bilayers (Organic & Biomolecular Chemistry) Friday February 12th 2010 49) The first diastereoselective synthesis of cinerins A-C, PAF-antagonistic macrophyllin-type bicyclo[3.2.1]octane neolignans, using a novel Pd-catalysed oxyarylation (Organic & Biomolecular Chemistry) Friday February 12th 2010 50) The effects of tryptophan and hydrophobicity on the structure and bioactivity of novel indolicidin derivatives with promising pharmaceutical potential (Organic & Biomolecular Chemistry) Thursday February 11th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote View: prev | next

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