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1) A general design strategy for protein-responsive riboswitches in mammalian cells (Nature Methods) Sunday October 12th 2014
Simon Ausl, Pascal St, Charlotte Rehm, David Ausl, J, Martin Fussenegger

2) Intracellular autofluorescence: a biomarker for epithelial cancer stem cells (Nature Methods) Sunday October 12th 2014
Irene Miranda-Lorenzo, Jorge Dorado, Enza Lonardo, Sonia Alcala, Alicia G Serrano, Jenifer Clausell-Tormos, Michele Cioffi, Diego Megias, Sladjana Zagorac, Anamaria Balic, Manuel Hidalgo, Mert Erkan, Joerg Kleeff, Aldo Scarpa, Bruno Sainz, Christopher Heeschen

3) Small molecules facilitate rapid and synchronous iPSC generation (Nature Methods) Sunday October 12th 2014
Ori Bar-Nur, Justin Brumbaugh, Cassandra Verheul, Effie Apostolou, Iulian Pruteanu-Malinici, Ryan M Walsh, Sridhar Ramaswamy, Konrad Hochedlinger

4) Predicting the human epigenome from DNA motifs (Nature Methods) Sunday October 12th 2014
John W Whitaker, Zhao Chen, Wei Wang

5) A quantitative framework for the forward design of synthetic miRNA circuits (Nature Methods) Sunday October 12th 2014
Ryan J Bloom, Sally M Winkler, Christina D Smolke

6) Nanoparticle vesicle encoding for imaging and tracking cell populations (Nature Methods) Sunday October 12th 2014
Paul Rees, John W Wills, M Rowan Brown, James Tonkin, Mark D Holton, Nicole Hondow, Andrew P Brown, Rik Brydson, Val Millar, Anne E Carpenter, Huw D Summers

7) A DNA-based molecular probe for optically reporting cellular traction forces (Nature Methods) Sunday October 12th 2014
Brandon L Blakely, Christoph E Dumelin, Britta Trappmann, Lynn M McGregor, Colin K Choi, Peter C Anthony, Van K Duesterberg, Brendon M Baker, Steven M Block, David R Liu, Christopher S Chen

8) An improved surface passivation method for single-molecule studies (Nature Methods) Sunday October 12th 2014
Boyang Hua, Kyu Young Han, Ruobo Zhou, Hajin Kim, Xinghua Shi, Sanjaya C Abeysirigunawardena, Ankur Jain, Digvijay Singh, Vasudha Aggarwal, Sarah A Woodson, Taekjip Ha

9) Time-resolved crystallography using the Hadamard transform (Nature Methods) Sunday October 12th 2014
Briony A Yorke, Godfrey S Beddard, Robin L Owen, Arwen R Pearson

10) Reconstruction of vocal interactions in a group of small songbirds (Nature Methods) Sunday October 12th 2014
Victor N Anisimov, Joshua A Herbst, Andrei N Abramchuk, Alexander V Latanov, Richard H R Hahnloser, Alexei L Vyssotski

11) Comprehensive analysis of DNA methylation data with RnBeads (Nature Methods) Sunday October 12th 2014
Yassen Assenov, Fabian M, Pavlo Lutsik, J, Thomas Lengauer, Christoph Bock

12) 3D genome reconstruction from chromosomal contacts (Nature Methods) Sunday October 12th 2014
Annick Lesne, Julien Riposo, Paul Roger, Axel Cournac, Julien Mozziconacci

13) Binning metagenomic contigs by coverage and composition (Nature Methods) Sunday October 12th 2014
Johannes Alneberg, Brynjar Sm, Ino de Bruijn, Melanie Schirmer, Joshua Quick, Umer Z Ijaz, Leo Lahti, Nicholas J Loman, Anders F Andersson, Christopher Quince

14) From genes to protein mechanics on a chip (Nature Methods) Sunday October 12th 2014
Marcus Otten, Wolfgang Ott, Markus A Jobst, Lukas F Milles, Tobias Verdorfer, Diana A Pippig, Michael A Nash, Hermann E Gaub

15) Light-sheet functional imaging in fictively behaving zebrafish (Nature Methods) Sunday August 17th 2014
Nikita Vladimirov, Yu Mu, Takashi Kawashima, Davis V Bennett, Chao-Tsung Yang, Loren L Looger, Philipp J Keller, Jeremy Freeman, Misha B Ahrens

16) Mapping brain activity at scale with cluster computing (Nature Methods) Sunday August 17th 2014
Jeremy Freeman, Nikita Vladimirov, Takashi Kawashima, Yu Mu, Nicholas J Sofroniew, Davis V Bennett, Joshua Rosen, Chao-Tsung Yang, Loren L Looger, Misha B Ahrens

17) Multiplexed aberration measurement for deep tissue imaging in vivo (Nature Methods) Sunday August 17th 2014
Chen Wang, Rui Liu, Daniel E Milkie, Wenzhi Sun, Zhongchao Tan, Aaron Kerlin, Tsai-Wen Chen, Douglas S Kim, Na Ji

18) Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser (Nature Methods) Sunday August 17th 2014
David Arnlund, Linda C Johansson, Cecilia Wickstrand, Anton Barty, Garth J Williams, Erik Malmerberg, Jan Davidsson, Despina Milathianaki, Daniel P DePonte, Robert L Shoeman, Dingjie Wang, Daniel James, Gergely Katona, Sebastian Westenhoff, Thomas A White, Andrew Aquila, Sadia Bari, Peter Berntsen, Mike Bogan, Tim Brandt van Driel, R Bruce Doak, Kasper Skov Kj, Matthias Frank, Raimund Fromme, Ingo Grotjohann, Robert Henning, Mark S Hunter, Richard A Kirian, Irina Kosheleva, Christopher Kupitz, Mengning Liang, Andrew V Martin, Martin Meedom Nielsen, Marc Messerschmidt, M Marvin Seibert, Jennie Sj, Francesco Stellato, Uwe Weierstall, Nadia A Zatsepin, John C H Spence, Petra Fromme, Ilme Schlichting, S, Gerrit Groenhof, Henry N Chapman, Richard Neutze

19) Efficient CRISPR-Cas9 (Nature Methods) Sunday August 17th 2014
Jeffrey C Wagner, Randall J Platt, Stephen J Goldfless, Feng Zhang, Jacquin C Niles

20) Epiviz: interactive visual analytics for functional genomics data (Nature Methods) Sunday August 17th 2014
Florin Chelaru, Llewellyn Smith, Naomi Goldstein, H

21) Phen-Gen: combining phenotype and genotype to analyze rare disorders (Nature Methods) Sunday August 17th 2014
Asif Javed, Saloni Agrawal, Pauline C Ng

22) Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes (Nature Methods) Sunday August 17th 2014
Signe Mathiasen, Sune M Christensen, Juan Jos, S, Jonathan F Fay, Sune K Jorgensen, Salome Veshaguri, David L Farrens, Maria Kiskowski, Brian Kobilka, Dimitrios Stamou

23) High-resolution structure determination by continuous-rotation data collection in MicroED (Nature Methods) Sunday August 17th 2014
Brent L Nannenga, Dan Shi, Andrew G W Leslie, Tamir Gonen

24) Isolation of rare recombinants without using selectable markers for one-step seamless BAC mutagenesis (Nature Methods) Sunday July 20th 2014
George T Lyozin, Paul C Bressloff, Amit Kumar, Yasuhiro Kosaka, Bradley L Demarest, H Joseph Yost, Michael R Kuehn, Luca Brunelli

25) RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP) (Nature Methods) Sunday July 20th 2014
Nathan A Siegfried, Steven Busan, Greggory M Rice, Julie A E Nelson, Kevin M Weeks

26) Fast, accurate reconstruction of cell lineages from large-scale fluorescence microscopy data (Nature Methods) Sunday July 20th 2014
Fernando Amat, William Lemon, Daniel P Mossing, Katie McDole, Yinan Wan, Kristin Branson, Eugene W Myers, Philipp J Keller

27) High-resolution reconstruction of the beating zebrafish heart (Nature Methods) Sunday July 20th 2014
Michaela Mickoleit, Benjamin Schmid, Michael Weber, Florian O Fahrbach, Sonja Hombach, Sven Reischauer, Jan Huisken

28) Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity (Nature Methods) Sunday July 20th 2014
S, Heather J Lee, Christof Angermueller, Felix Krueger, Heba Saadeh, Julian Peat, Simon R Andrews, Oliver Stegle, Wolf Reik, Gavin Kelsey

29) Optimized cell transplantation using adult rag2 mutant zebrafish (Nature Methods) Sunday July 20th 2014
Qin Tang, Nouran S Abdelfattah, Jessica S Blackburn, John C Moore, Sarah A Martinez, Finola E Moore, Riadh Lobbardi, In, Myron S Ignatius, Jason N Berman, Robert S Liwski, Yariv Houvras, David M Langenau

30) Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries (Nature Methods) Sunday July 6th 2014
Uyen T T Nguyen, Lenka Bittova, Manuel M M, Beat Fierz, Yael David, Brian Houck-Loomis, Vanessa Feng, Geoffrey P Dann, Tom W Muir

31) Spatial control of membrane receptor function using ligand nanocalipers (Nature Methods) Sunday July 6th 2014
Alan Shaw, Vanessa Lundin, Ekaterina Petrova, Ferenc F, Erik Benson, Abdullah Al-Amin, Anna Herland, Andries Blokzijl, Bj, Ana I Teixeira

32) A method to recapitulate early embryonic spatial patterning in human embryonic stem cells (Nature Methods) Sunday June 29th 2014
Aryeh Warmflash, Benoit Sorre, Fred Etoc, Eric D Siggia, Ali H Brivanlou

33) All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins (Nature Methods) Sunday June 22nd 2014
Daniel R Hochbaum, Yongxin Zhao, Samouil L Farhi, Nathan Klapoetke, Christopher A Werley, Vikrant Kapoor, Peng Zou, Joel M Kralj, Dougal Maclaurin, Niklas Smedemark-Margulies, Jessica L Saulnier, Gabriella L Boulting, Christoph Straub, Yong Ku Cho, Michael Melkonian, Gane Ka-Shu Wong, D Jed Harrison, Venkatesh N Murthy, Bernardo L Sabatini, Edward S Boyden, Robert E Campbell, Adam E Cohen

34) Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics (Nature Methods) Sunday June 22nd 2014
Alicia Lundby, Elizabeth J Rossin, Annette B Steffensen, Moshe Rav Acha, Christopher Newton-Cheh, Arne Pfeufer, Stacey N Lynch, S, S, Patrick T Ellinor, J Wouter Jukema, Stella Trompet, Ian Ford, Peter W Macfarlane, Bouwe P Krijthe, Albert Hofman, Andr, Bruno H Stricker, Hendrik M Nathoe, Wilko Spiering, Mark J Daly, Folkert W Asselbergs, Pim van der Harst, David J Milan, Paul I W de Bakker, Kasper Lage, Jesper V Olsen

35) Chemically defined generation of human cardiomyocytes (Nature Methods) Sunday June 15th 2014
Paul W Burridge, Elena Matsa, Praveen Shukla, Ziliang C Lin, Jared M Churko, Antje D Ebert, Feng Lan, Sebastian Diecke, Bruno Huber, Nicholas M Mordwinkin, Jordan R Plews, Oscar J Abilez, Bianxiao Cui, Joseph D Gold, Joseph C Wu

36) Protein delivery into live cells by incubation with an endosomolytic agent (Nature Methods) Sunday June 15th 2014
Alfredo Erazo-Oliveras, Kristina Najjar, Laila Dayani, Ting-Yi Wang, Gregory A Johnson, Jean-Philippe Pellois

37) Targeting cells with single vectors using multiple-feature Boolean logic (Nature Methods) Sunday June 8th 2014
Lief E Fenno, Joanna Mattis, Charu Ramakrishnan, Minsuk Hyun, Soo Yeun Lee, Miao He, Jason Tucciarone, Aslihan Selimbeyoglu, Andre Berndt, Logan Grosenick, Kelly A Zalocusky, Hannah Bernstein, Haley Swanson, Chelsey Perry, Ilka Diester, Frederick M Boyce, Caroline E Bass, Rachael Neve, Z Josh Huang, Karl Deisseroth

38) Single-cell western blotting (Nature Methods) Sunday June 1st 2014
Alex J Hughes, Dawn P Spelke, Zhuchen Xu, Chi-Chih Kang, David V Schaffer, Amy E Herr

39) idTracker: tracking individuals in a group by automatic identification of unmarked animals (Nature Methods) Sunday June 1st 2014
Alfonso P, Juli, Robert C Hinz, Sara Arganda, Gonzalo G de Polavieja

40) FlyMAD: rapid thermogenetic control of neuronal activity in freely walking Drosophila (Nature Methods) Sunday June 1st 2014
Daniel E Bath, John R Stowers, Dorothea H, Andreas Poehlmann, Barry J Dickson, Andrew D Straw

41) Comprehensive analysis of RNA-protein interactions by high-throughput sequencing (Nature Methods) Sunday May 18th 2014
Jacob M Tome, Abdullah Ozer, John M Pagano, Dan Gheba, Gary P Schroth, John T Lis

42) Bayesian approach to single-cell differential expression analysis (Nature Methods) Sunday May 18th 2014
Peter V Kharchenko, Lev Silberstein, David T Scadden

43) Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy (Nature Methods) Sunday May 18th 2014
Robert Prevedel, Young-Gyu Yoon, Maximilian Hoffmann, Nikita Pak, Gordon Wetzstein, Saul Kato, Tina Schr, Ramesh Raskar, Manuel Zimmer, Edward S Boyden, Alipasha Vaziri

44) Correlated cryogenic photoactivated localization microscopy and cryo-electron tomography (Nature Methods) Sunday May 18th 2014
Yi-Wei Chang, Songye Chen, Elitza I Tocheva, Anke Treuner-Lange, Stephanie L, Lotte S, Grant J Jensen

45) Determination of damage-free crystal structure of an X-ray (Nature Methods) Sunday May 18th 2014
Kunio Hirata, Kyoko Shinzawa-Itoh, Naomine Yano, Shuhei Takemura, Koji Kato, Miki Hatanaka, Kazumasa Muramoto, Takako Kawahara, Tomitake Tsukihara, Eiki Yamashita, Kensuke Tono, Go Ueno, Takaaki Hikima, Hironori Murakami, Yuichi Inubushi, Makina Yabashi, Tetsuya Ishikawa, Masaki Yamamoto, Takashi Ogura, Hiroshi Sugimoto, Jian-Ren Shen, Shinya Yoshikawa, Hideo Ago

46) CRISPR transcriptional repression devices and layered circuits in mammalian cells (Nature Methods) Monday May 5th 2014
Samira Kiani, Jacob Beal, Mohammad R Ebrahimkhani, Jin Huh, Richard N Hall, Zhen Xie, Yinqing Li, Ron Weiss

47) Bone marrow (Nature Methods) Sunday May 4th 2014
Yu-suke Torisawa, Catherine S Spina, Tadanori Mammoto, Akiko Mammoto, James C Weaver, Tracy Tat, James J Collins, Donald E Ingber

48) Reversible protein inactivation by optogenetic trapping in cells (Nature Methods) Sunday May 4th 2014
Sangkyu Lee, Hyerim Park, Taeyoon Kyung, Na Yeon Kim, Sungsoo Kim, Jihoon Kim, Won Do Heo

49) Towards error-free profiling of immune repertoires (Nature Methods) Sunday May 4th 2014
Mikhail Shugay, Olga V Britanova, Ekaterina M Merzlyak, Maria A Turchaninova, Ilgar Z Mamedov, Timur R Tuganbaev, Dmitriy A Bolotin, Dmitry B Staroverov, Ekaterina V Putintseva, Karla Plevova, Carsten Linnemann, Dmitriy Shagin, Sarka Pospisilova, Sergey Lukyanov, Ton N Schumacher, Dmitriy M Chudakov

50) Interactive assembly algorithms for molecular cloning (Nature Methods) Monday April 28th 2014
Evan Appleton, Jenhan Tao, Traci Haddock, Douglas Densmore

51) Chronic, wireless recordings of large-scale brain activity in freely moving rhesus monkeys (Nature Methods) Monday April 28th 2014
David A Schwarz, Mikhail A Lebedev, Timothy L Hanson, Dragan F Dimitrov, Gary Lehew, Jim Meloy, Sankaranarayani Rajangam, Vivek Subramanian, Peter J Ifft, Zheng Li, Arjun Ramakrishnan, Andrew Tate, Katie Z Zhuang, Miguel A L Nicolelis

52) Olfactory exposure to males, including men, causes stress and related analgesia in rodents (Nature Methods) Monday April 28th 2014
Robert E Sorge, Loren J Martin, Kelsey A Isbester, Susana G Sotocinal, Sarah Rosen, Alexander H Tuttle, Jeffrey S Wieskopf, Erinn L Acland, Anastassia Dokova, Basil Kadoura, Philip Leger, Josiane C S Mapplebeck, Martina McPhail, Ada Delaney, Gustaf Wigerblad, Alan P Schumann, Tammie Quinn, Johannes Frasnelli, Camilla I Svensson, Wendy F Sternberg, Jeffrey S Mogil

53) Validation of noise models for single-cell transcriptomics (Nature Methods) Sunday April 20th 2014
Dominic Gr, Lennart Kester, Alexander van Oudenaarden

54) Efficient Bayesian-based multiview deconvolution (Nature Methods) Sunday April 20th 2014
Stephan Preibisch, Fernando Amat, Evangelia Stamataki, Mihail Sarov, Robert H Singer, Eugene Myers, Pavel Tomancak

55) Controlling protein adsorption on graphene for cryo-EM using low-energy hydrogen plasmas (Nature Methods) Sunday April 20th 2014
Christopher J Russo, Lori A Passmore

56) An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions (Nature Methods) Sunday April 20th 2014
Emmanuelle Tchekanda, Durga Sivanesan, Stephen W Michnick

57) Multiscale representation of genomic signals (Nature Methods) Sunday April 13th 2014
Theo A Knijnenburg, Stephen A Ramsey, Benjamin P Berman, Kathleen A Kennedy, Arian F A Smit, Lodewyk F A Wessels, Peter W Laird, Alan Aderem, Ilya Shmulevich

58) Single-molecule analysis of cell surface dynamics in Caenorhabditis elegans embryos (Nature Methods) Sunday April 13th 2014
Fran, William M McFadden, Baixue Yao, Edwin M Munro

59) Rapid adaptive optical recovery of optimal resolution over large volumes (Nature Methods) Sunday April 13th 2014
Kai Wang, Daniel E Milkie, Ankur Saxena, Peter Engerer, Thomas Misgeld, Marianne E Bronner, Jeff Mumm, Eric Betzig

60) Fluorescence nanoscopy by polarization modulation and polarization angle narrowing (Nature Methods) Sunday April 6th 2014
Nour Hafi, Matthias Grunwald, Laura S van den Heuvel, Timo Aspelmeier, Jian-Hua Chen, Marta Zagrebelsky, Ole M Sch, Claudia Steinem, Martin Korte, Axel Munk, Peter J Walla

61) Light-sheet microscopy using an Airy beam (Nature Methods) Sunday April 6th 2014
Tom Vettenburg, Heather I C Dalgarno, Jonathan Nylk, Clara Coll-Llad, David E K Ferrier, Tom, Frank J Gunn-Moore, Kishan Dholakia

62) Measuring similarity between dynamic ensembles of biomolecules (Nature Methods) Sunday April 6th 2014
Shan Yang, Lo, Hashim M Al-Hashimi

63) Quantifying Drosophila food intake: comparative analysis of current methodology (Nature Methods) Sunday March 30th 2014
Sonali A Deshpande, Gil B Carvalho, Ariadna Amador, Angela M Phillips, Sany Hoxha, Keith J Lizotte, William W Ja

64) Transcriptional profiling of cells sorted by RNA abundance (Nature Methods) Sunday March 30th 2014
Sandy Klemm, Stefan Semrau, Kay Wiebrands, Dylan Mooijman, Dina A Faddah, Rudolf Jaenisch, Alexander van Oudenaarden

65) Function-based identification of mammalian enhancers using site-specific integration (Nature Methods) Sunday March 23rd 2014
Diane E Dickel, Yiwen Zhu, Alex S Nord, John N Wylie, Jennifer A Akiyama, Veena Afzal, Ingrid Plajzer-Frick, Aileen Kirkpatrick, Berthold G, Benoit G Bruneau, Axel Visel, Len A Pennacchio

66) FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells (Nature Methods) Sunday March 23rd 2014
Matthew Murtha, Zeynep Tokcaer-Keskin, Zuojian Tang, Francesco Strino, Xi Chen, Yatong Wang, Xiangmei Xi, Claudio Basilico, Stuart Brown, Richard Bonneau, Yuval Kluger, Lisa Dailey

67) The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells (Nature Methods) Sunday March 23rd 2014
Julia Petschnigg, Bella Groisman, Max Kotlyar, Mikko Taipale, Yong Zheng, Christoph F Kurat, Azin Sayad, J Rafael Sierra, Mojca Mattiazzi Usaj, Jamie Snider, Alex Nachman, Irina Krykbaeva, Ming-Sound Tsao, Jason Moffat, Tony Pawson, Susan Lindquist, Igor Jurisica, Igor Stagljar

68) Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon (Nature Methods) Monday March 17th 2014
Christian Fr, M Wayne Davis, Mihail Sarov, Jon Taylor, Stephane Flibotte, Matthew LaBella, Andrei Pozniakovski, Donald G Moerman, Erik M Jorgensen

69) Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein (Nature Methods) Monday March 17th 2014
Jun Chu, Russell D Haynes, St, Pengpeng Li, Emilio Gonz, John S Burg, Niloufar J Ataie, Amy J Lam, Paula J Cranfill, Michelle A Baird, Michael W Davidson, Ho-Leung Ng, K Christopher Garcia, Christopher H Contag, Kang Shen, Helen M Blau, Michael Z Lin

70) Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers (Nature Methods) Monday March 17th 2014
Johan Hattne, Nathaniel Echols, Rosalie Tran, Jan Kern, Richard J Gildea, Aaron S Brewster, Roberto Alonso-Mori, Carina Gl, Julia Hellmich, Hartawan Laksmono, Raymond G Sierra, Benedikt Lassalle-Kaiser, Alyssa Lampe, Guangye Han, Sheraz Gul, D, Despina Milathianaki, Alan R Fry, Alan Miahnahri, William E White, Donald W Schafer, M Marvin Seibert, Jason E Koglin, Dimosthenis Sokaras, Tsu-Chien Weng, Jonas Sellberg, Matthew J Latimer, Pieter Glatzel, Petrus H Zwart, Ralf W Grosse-Kunstleve, Michael J Bogan, Marc Messerschmidt, Garth J Williams, S, Johannes Messinger, Athina Zouni, Junko Yano, Uwe Bergmann, Vittal K Yachandra, Paul D Adams, Nicholas K Sauter

71) PyClone: statistical inference of clonal population structure in cancer (Nature Methods) Monday March 17th 2014
Andrew Roth, Jaswinder Khattra, Damian Yap, Adrian Wan, Emma Laks, Justina Biele, Gavin Ha, Samuel Aparicio, Alexandre Bouchard-C, Sohrab P Shah

72) Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals (Nature Methods) Sunday March 9th 2014
Evan J Olson, Lucas A Hartsough, Brian P Landry, Raghav Shroff, Jeffrey J Tabor

73) Dynamic characterization of growth and gene expression using high-throughput automated flow cytometry (Nature Methods) Sunday March 9th 2014
Ignacio A Zuleta, Andr, Hao Li, Hana El-Samad

74) Single-molecule motions enable direct visualization of biomolecular interactions in solution (Nature Methods) Sunday March 9th 2014
Quan Wang, W E Moerner

75) Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry (Nature Methods) Sunday March 2nd 2014
Charlotte Giesen, Hao A O Wang, Denis Schapiro, Nevena Zivanovic, Andrea Jacobs, Bodo Hattendorf, Peter J Sch, Daniel Grolimund, Joachim M Buhmann, Simone Brandt, Zsuzsanna Varga, Peter J Wild, Detlef G, Bernd Bodenmiller

76) Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects (Nature Methods) Sunday March 2nd 2014
Bin Shen, Wensheng Zhang, Jun Zhang, Jiankui Zhou, Jianying Wang, Li Chen, Lu Wang, Alex Hodgkins, Vivek Iyer, Xingxu Huang, William C Skarnes

77) Structure determination of noncanonical RNA motifs guided by 1H NMR chemical shifts (Nature Methods) Sunday March 2nd 2014
Parin Sripakdeevong, Mirko Cevec, Andrew T Chang, Mich, Melanie Ziegeler, Qin Zhao, George E Fox, Xiaolian Gao, Scott D Kennedy, Ryszard Kierzek, Edward P Nikonowicz, Harald Schwalbe, Roland K O Sigel, Douglas H Turner, Rhiju Das

78) Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering (Nature Methods) Sunday March 2nd 2014
Lu Wei, Fanghao Hu, Yihui Shen, Zhixing Chen, Yong Yu, Chih-Chun Lin, Meng C Wang, Wei Min

79) Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods (Nature Methods) Sunday February 23rd 2014
Simon C Warby, Sabrina L Wendt, Peter Welinder, Emil G S Munk, Oscar Carrillo, Helge B D Sorensen, Poul Jennum, Paul E Peppard, Pietro Perona, Emmanuel Mignot

80) Gold rotor bead tracking for high-speed measurements of DNA twist, torque and extension (Nature Methods) Sunday February 23rd 2014
Paul Lebel, Aakash Basu, Florian C Oberstrass, Elsa M Tretter, Zev Bryant

81) Identification of small molecules that support human leukemia stem cell activity ex vivo (Nature Methods) Sunday February 23rd 2014
Caroline Pabst, Jana Krosl, Iman Fares, Genevi, R, Anne Marinier, S, Jos, Guy Sauvageau

82) Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity (Nature Methods) Sunday February 16th 2014
John P Guilinger, Vikram Pattanayak, Deepak Reyon, Shengdar Q Tsai, Jeffry D Sander, J Keith Joung, David R Liu

83) Cryo-scanning transmission electron tomography of vitrified cells (Nature Methods) Sunday February 16th 2014
Sharon Grayer Wolf, Lothar Houben, Michael Elbaum

84) Efficient multivariate linear mixed model algorithms for genome-wide association studies (Nature Methods) Sunday February 16th 2014
Xiang Zhou, Matthew Stephens

85) Independent optical excitation of distinct neural populations (Nature Methods) Sunday February 9th 2014
Nathan C Klapoetke, Yasunobu Murata, Sung Soo Kim, Stefan R Pulver, Amanda Birdsey-Benson, Yong Ku Cho, Tania K Morimoto, Amy S Chuong, Eric J Carpenter, Zhijian Tian, Jun Wang, Yinlong Xie, Zhixiang Yan, Yong Zhang, Brian Y Chow, Barbara Surek, Michael Melkonian, Vivek Jayaraman, Martha Constantine-Paton, Gane Ka-Shu Wong, Edward S Boyden

86) A synthetic luciferin improves bioluminescence imaging in live mice (Nature Methods) Sunday February 9th 2014
Melanie S Evans, Joanna P Chaurette, Spencer T Adams, Gadarla R Reddy, Miranwda A Paley, Neil Aronin, Jennifer A Prescher, Stephen C Miller

87) Isolation of single-base genome-edited human iPS cells without antibiotic selection (Nature Methods) Sunday February 9th 2014
Yuichiro Miyaoka, Amanda H Chan, Luke M Judge, Jennie Yoo, Miller Huang, Trieu D Nguyen, Paweena P Lizarraga, Po-Lin So, Bruce R Conklin

88) A mass spectrometry (Nature Methods) Sunday February 9th 2014
Argyris Politis, Florian Stengel, Zoe Hall, Helena Hern, Alexander Leitner, Thomas Walzthoeni, Carol V Robinson, Ruedi Aebersold

89) Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT (Nature Methods) Sunday February 2nd 2014
Ralf Jungmann, Maier S Avenda, Johannes B Woehrstein, Mingjie Dai, William M Shih, Peng Yin

90) Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells (Nature Methods) Sunday February 2nd 2014
Nils A Kulak, Garwin Pichler, Igor Paron, Nagarjuna Nagaraj, Matthias Mann

91) Functional annotation of noncoding sequence variants (Nature Methods) Sunday February 2nd 2014
Graham R S Ritchie, Ian Dunham, Eleftheria Zeggini, Paul Flicek

92) Similarity network fusion for aggregating data types on a genomic scale (Nature Methods) Sunday January 26th 2014
Bo Wang, Aziz M Mezlini, Feyyaz Demir, Marc Fiume, Zhuowen Tu, Michael Brudno, Benjamin Haibe-Kains, Anna Goldenberg

93) Correlative super-resolution fluorescence and metal-replica transmission electron microscopy (Nature Methods) Sunday January 26th 2014
Kem A Sochacki, Gleb Shtengel, Schuyler B van Engelenburg, Harald F Hess, Justin W Taraska

94) Epigenome-wide association studies without the need for cell-type composition (Nature Methods) Sunday January 26th 2014
James Zou, Christoph Lippert, David Heckerman, Martin Aryee, Jennifer Listgarten

95) Objective comparison of particle tracking methods (Nature Methods) Sunday January 19th 2014
Nicolas Chenouard, Ihor Smal, Fabrice de Chaumont, Martin Ma, Ivo F Sbalzarini, Yuanhao Gong, Janick Cardinale, Craig Carthel, Stefano Coraluppi, Mark Winter, Andrew R Cohen, William J Godinez, Karl Rohr, Yannis Kalaidzidis, Liang Liang, James Duncan, Hongying Shen, Yingke Xu, Klas E G Magnusson, Joakim Jald, Helen M Blau, Perrine Paul-Gilloteaux, Philippe Roudot, Charles Kervrann, Fran, Jean-Yves Tinevez, Spencer L Shorte, Joost Willemse, Katherine Celler, Gilles P van Wezel, Han-Wei Dan, Yuh-Show Tsai, Carlos Ortiz de Sol, Jean-Christophe Olivo-Marin, Erik Meijering

96) Targeted protein quantification using sparse reference labeling (Nature Methods) Sunday January 19th 2014
Ching-Yun Chang, Eduard Sabid, Ruedi Aebersold, Olga Vitek

97) Continuous throughput and long-term observation of single-molecule FRET without immobilization (Nature Methods) Sunday January 19th 2014
Swati Tyagi, Virginia VanDelinder, Niccol, Gustavo Fuertes, Sigrid Milles, Morgane Agez, Edward A Lemke

98) Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue (Nature Methods) Monday January 13th 2014
Ditte Lovatt, Brittani K Ruble, Jaehee Lee, Hannah Dueck, Tae Kyung Kim, Stephen Fisher, Chantal Francis, Jennifer M Spaethling, John A Wolf, M Sean Grady, Alexandra V Ulyanova, Sean B Yeldell, Julianne C Griepenburg, Peter T Buckley, Junhyong Kim, Jai-Yoon Sul, Ivan J Dmochowski, James Eberwine

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