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1) Validation of noise models for single-cell transcriptomics (Nature Methods) Sunday April 20th 2014
Dominic Gr, Lennart Kester, Alexander van Oudenaarden

2) Efficient Bayesian-based multiview deconvolution (Nature Methods) Sunday April 20th 2014
Stephan Preibisch, Fernando Amat, Evangelia Stamataki, Mihail Sarov, Robert H Singer, Eugene Myers, Pavel Tomancak

3) Controlling protein adsorption on graphene for cryo-EM using low-energy hydrogen plasmas (Nature Methods) Sunday April 20th 2014
Christopher J Russo, Lori A Passmore

4) An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions (Nature Methods) Sunday April 20th 2014
Emmanuelle Tchekanda, Durga Sivanesan, Stephen W Michnick

5) Multiscale representation of genomic signals (Nature Methods) Sunday April 13th 2014
Theo A Knijnenburg, Stephen A Ramsey, Benjamin P Berman, Kathleen A Kennedy, Arian F A Smit, Lodewyk F A Wessels, Peter W Laird, Alan Aderem, Ilya Shmulevich

6) Single-molecule analysis of cell surface dynamics in Caenorhabditis elegans embryos (Nature Methods) Sunday April 13th 2014
Fran, William M McFadden, Baixue Yao, Edwin M Munro

7) Rapid adaptive optical recovery of optimal resolution over large volumes (Nature Methods) Sunday April 13th 2014
Kai Wang, Daniel E Milkie, Ankur Saxena, Peter Engerer, Thomas Misgeld, Marianne E Bronner, Jeff Mumm, Eric Betzig

8) Fluorescence nanoscopy by polarization modulation and polarization angle narrowing (Nature Methods) Sunday April 6th 2014
Nour Hafi, Matthias Grunwald, Laura S van den Heuvel, Timo Aspelmeier, Jian-Hua Chen, Marta Zagrebelsky, Ole M Sch, Claudia Steinem, Martin Korte, Axel Munk, Peter J Walla

9) Light-sheet microscopy using an Airy beam (Nature Methods) Sunday April 6th 2014
Tom Vettenburg, Heather I C Dalgarno, Jonathan Nylk, Clara Coll-Llad, David E K Ferrier, Tom, Frank J Gunn-Moore, Kishan Dholakia

10) Measuring similarity between dynamic ensembles of biomolecules (Nature Methods) Sunday April 6th 2014
Shan Yang, Lo, Hashim M Al-Hashimi

11) Quantifying Drosophila food intake: comparative analysis of current methodology (Nature Methods) Sunday March 30th 2014
Sonali A Deshpande, Gil B Carvalho, Ariadna Amador, Angela M Phillips, Sany Hoxha, Keith J Lizotte, William W Ja

12) Transcriptional profiling of cells sorted by RNA abundance (Nature Methods) Sunday March 30th 2014
Sandy Klemm, Stefan Semrau, Kay Wiebrands, Dylan Mooijman, Dina A Faddah, Rudolf Jaenisch, Alexander van Oudenaarden

13) Function-based identification of mammalian enhancers using site-specific integration (Nature Methods) Sunday March 23rd 2014
Diane E Dickel, Yiwen Zhu, Alex S Nord, John N Wylie, Jennifer A Akiyama, Veena Afzal, Ingrid Plajzer-Frick, Aileen Kirkpatrick, Berthold G, Benoit G Bruneau, Axel Visel, Len A Pennacchio

14) FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells (Nature Methods) Sunday March 23rd 2014
Matthew Murtha, Zeynep Tokcaer-Keskin, Zuojian Tang, Francesco Strino, Xi Chen, Yatong Wang, Xiangmei Xi, Claudio Basilico, Stuart Brown, Richard Bonneau, Yuval Kluger, Lisa Dailey

15) The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells (Nature Methods) Sunday March 23rd 2014
Julia Petschnigg, Bella Groisman, Max Kotlyar, Mikko Taipale, Yong Zheng, Christoph F Kurat, Azin Sayad, J Rafael Sierra, Mojca Mattiazzi Usaj, Jamie Snider, Alex Nachman, Irina Krykbaeva, Ming-Sound Tsao, Jason Moffat, Tony Pawson, Susan Lindquist, Igor Jurisica, Igor Stagljar

16) Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon (Nature Methods) Monday March 17th 2014
Christian Fr, M Wayne Davis, Mihail Sarov, Jon Taylor, Stephane Flibotte, Matthew LaBella, Andrei Pozniakovski, Donald G Moerman, Erik M Jorgensen

17) Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein (Nature Methods) Monday March 17th 2014
Jun Chu, Russell D Haynes, St, Pengpeng Li, Emilio Gonz, John S Burg, Niloufar J Ataie, Amy J Lam, Paula J Cranfill, Michelle A Baird, Michael W Davidson, Ho-Leung Ng, K Christopher Garcia, Christopher H Contag, Kang Shen, Helen M Blau, Michael Z Lin

18) Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers (Nature Methods) Monday March 17th 2014
Johan Hattne, Nathaniel Echols, Rosalie Tran, Jan Kern, Richard J Gildea, Aaron S Brewster, Roberto Alonso-Mori, Carina Gl, Julia Hellmich, Hartawan Laksmono, Raymond G Sierra, Benedikt Lassalle-Kaiser, Alyssa Lampe, Guangye Han, Sheraz Gul, D, Despina Milathianaki, Alan R Fry, Alan Miahnahri, William E White, Donald W Schafer, M Marvin Seibert, Jason E Koglin, Dimosthenis Sokaras, Tsu-Chien Weng, Jonas Sellberg, Matthew J Latimer, Pieter Glatzel, Petrus H Zwart, Ralf W Grosse-Kunstleve, Michael J Bogan, Marc Messerschmidt, Garth J Williams, S, Johannes Messinger, Athina Zouni, Junko Yano, Uwe Bergmann, Vittal K Yachandra, Paul D Adams, Nicholas K Sauter

19) PyClone: statistical inference of clonal population structure in cancer (Nature Methods) Monday March 17th 2014
Andrew Roth, Jaswinder Khattra, Damian Yap, Adrian Wan, Emma Laks, Justina Biele, Gavin Ha, Samuel Aparicio, Alexandre Bouchard-C, Sohrab P Shah

20) Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals (Nature Methods) Sunday March 9th 2014
Evan J Olson, Lucas A Hartsough, Brian P Landry, Raghav Shroff, Jeffrey J Tabor

21) Dynamic characterization of growth and gene expression using high-throughput automated flow cytometry (Nature Methods) Sunday March 9th 2014
Ignacio A Zuleta, Andr, Hao Li, Hana El-Samad

22) Single-molecule motions enable direct visualization of biomolecular interactions in solution (Nature Methods) Sunday March 9th 2014
Quan Wang, W E Moerner

23) Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry (Nature Methods) Sunday March 2nd 2014
Charlotte Giesen, Hao A O Wang, Denis Schapiro, Nevena Zivanovic, Andrea Jacobs, Bodo Hattendorf, Peter J Sch, Daniel Grolimund, Joachim M Buhmann, Simone Brandt, Zsuzsanna Varga, Peter J Wild, Detlef G, Bernd Bodenmiller

24) Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects (Nature Methods) Sunday March 2nd 2014
Bin Shen, Wensheng Zhang, Jun Zhang, Jiankui Zhou, Jianying Wang, Li Chen, Lu Wang, Alex Hodgkins, Vivek Iyer, Xingxu Huang, William C Skarnes

25) Structure determination of noncanonical RNA motifs guided by 1H NMR chemical shifts (Nature Methods) Sunday March 2nd 2014
Parin Sripakdeevong, Mirko Cevec, Andrew T Chang, Mich, Melanie Ziegeler, Qin Zhao, George E Fox, Xiaolian Gao, Scott D Kennedy, Ryszard Kierzek, Edward P Nikonowicz, Harald Schwalbe, Roland K O Sigel, Douglas H Turner, Rhiju Das

26) Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering (Nature Methods) Sunday March 2nd 2014
Lu Wei, Fanghao Hu, Yihui Shen, Zhixing Chen, Yong Yu, Chih-Chun Lin, Meng C Wang, Wei Min

27) Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods (Nature Methods) Sunday February 23rd 2014
Simon C Warby, Sabrina L Wendt, Peter Welinder, Emil G S Munk, Oscar Carrillo, Helge B D Sorensen, Poul Jennum, Paul E Peppard, Pietro Perona, Emmanuel Mignot

28) Gold rotor bead tracking for high-speed measurements of DNA twist, torque and extension (Nature Methods) Sunday February 23rd 2014
Paul Lebel, Aakash Basu, Florian C Oberstrass, Elsa M Tretter, Zev Bryant

29) Identification of small molecules that support human leukemia stem cell activity ex vivo (Nature Methods) Sunday February 23rd 2014
Caroline Pabst, Jana Krosl, Iman Fares, Genevi, R, Anne Marinier, S, Jos, Guy Sauvageau

30) Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity (Nature Methods) Sunday February 16th 2014
John P Guilinger, Vikram Pattanayak, Deepak Reyon, Shengdar Q Tsai, Jeffry D Sander, J Keith Joung, David R Liu

31) Cryo-scanning transmission electron tomography of vitrified cells (Nature Methods) Sunday February 16th 2014
Sharon Grayer Wolf, Lothar Houben, Michael Elbaum

32) Efficient multivariate linear mixed model algorithms for genome-wide association studies (Nature Methods) Sunday February 16th 2014
Xiang Zhou, Matthew Stephens

33) Independent optical excitation of distinct neural populations (Nature Methods) Sunday February 9th 2014
Nathan C Klapoetke, Yasunobu Murata, Sung Soo Kim, Stefan R Pulver, Amanda Birdsey-Benson, Yong Ku Cho, Tania K Morimoto, Amy S Chuong, Eric J Carpenter, Zhijian Tian, Jun Wang, Yinlong Xie, Zhixiang Yan, Yong Zhang, Brian Y Chow, Barbara Surek, Michael Melkonian, Vivek Jayaraman, Martha Constantine-Paton, Gane Ka-Shu Wong, Edward S Boyden

34) A synthetic luciferin improves bioluminescence imaging in live mice (Nature Methods) Sunday February 9th 2014
Melanie S Evans, Joanna P Chaurette, Spencer T Adams, Gadarla R Reddy, Miranwda A Paley, Neil Aronin, Jennifer A Prescher, Stephen C Miller

35) Isolation of single-base genome-edited human iPS cells without antibiotic selection (Nature Methods) Sunday February 9th 2014
Yuichiro Miyaoka, Amanda H Chan, Luke M Judge, Jennie Yoo, Miller Huang, Trieu D Nguyen, Paweena P Lizarraga, Po-Lin So, Bruce R Conklin

36) A mass spectrometry (Nature Methods) Sunday February 9th 2014
Argyris Politis, Florian Stengel, Zoe Hall, Helena Hern, Alexander Leitner, Thomas Walzthoeni, Carol V Robinson, Ruedi Aebersold

37) Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT (Nature Methods) Sunday February 2nd 2014
Ralf Jungmann, Maier S Avenda, Johannes B Woehrstein, Mingjie Dai, William M Shih, Peng Yin

38) Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells (Nature Methods) Sunday February 2nd 2014
Nils A Kulak, Garwin Pichler, Igor Paron, Nagarjuna Nagaraj, Matthias Mann

39) Functional annotation of noncoding sequence variants (Nature Methods) Sunday February 2nd 2014
Graham R S Ritchie, Ian Dunham, Eleftheria Zeggini, Paul Flicek

40) Similarity network fusion for aggregating data types on a genomic scale (Nature Methods) Sunday January 26th 2014
Bo Wang, Aziz M Mezlini, Feyyaz Demir, Marc Fiume, Zhuowen Tu, Michael Brudno, Benjamin Haibe-Kains, Anna Goldenberg

41) Correlative super-resolution fluorescence and metal-replica transmission electron microscopy (Nature Methods) Sunday January 26th 2014
Kem A Sochacki, Gleb Shtengel, Schuyler B van Engelenburg, Harald F Hess, Justin W Taraska

42) Epigenome-wide association studies without the need for cell-type composition (Nature Methods) Sunday January 26th 2014
James Zou, Christoph Lippert, David Heckerman, Martin Aryee, Jennifer Listgarten

43) Objective comparison of particle tracking methods (Nature Methods) Sunday January 19th 2014
Nicolas Chenouard, Ihor Smal, Fabrice de Chaumont, Martin Ma, Ivo F Sbalzarini, Yuanhao Gong, Janick Cardinale, Craig Carthel, Stefano Coraluppi, Mark Winter, Andrew R Cohen, William J Godinez, Karl Rohr, Yannis Kalaidzidis, Liang Liang, James Duncan, Hongying Shen, Yingke Xu, Klas E G Magnusson, Joakim Jald, Helen M Blau, Perrine Paul-Gilloteaux, Philippe Roudot, Charles Kervrann, Fran, Jean-Yves Tinevez, Spencer L Shorte, Joost Willemse, Katherine Celler, Gilles P van Wezel, Han-Wei Dan, Yuh-Show Tsai, Carlos Ortiz de Sol, Jean-Christophe Olivo-Marin, Erik Meijering

44) Targeted protein quantification using sparse reference labeling (Nature Methods) Sunday January 19th 2014
Ching-Yun Chang, Eduard Sabid, Ruedi Aebersold, Olga Vitek

45) Continuous throughput and long-term observation of single-molecule FRET without immobilization (Nature Methods) Sunday January 19th 2014
Swati Tyagi, Virginia VanDelinder, Niccol, Gustavo Fuertes, Sigrid Milles, Morgane Agez, Edward A Lemke

46) Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue (Nature Methods) Monday January 13th 2014
Ditte Lovatt, Brittani K Ruble, Jaehee Lee, Hannah Dueck, Tae Kyung Kim, Stephen Fisher, Chantal Francis, Jennifer M Spaethling, John A Wolf, M Sean Grady, Alexandra V Ulyanova, Sean B Yeldell, Julianne C Griepenburg, Peter T Buckley, Junhyong Kim, Jai-Yoon Sul, Ivan J Dmochowski, James Eberwine

47) Scalable inference of heterogeneous reaction kinetics from pooled single-cell recordings (Nature Methods) Monday January 13th 2014
Christoph Zechner, Michael Unger, Serge Pelet, Matthias Peter, Heinz Koeppl

48) EC-BLAST: a tool to automatically search and compare enzyme reactions (Nature Methods) Monday January 13th 2014
Syed Asad Rahman, Sergio Martinez Cuesta, Nicholas Furnham, Gemma L Holliday, Janet M Thornton

49) Single-molecule evaluation of fluorescent protein photoactivation efficiency using an in vivo nanotemplate (Nature Methods) Sunday January 5th 2014
Nela Durisic, Lara Laparra-Cuervo, Ángel Sandoval-Álvarez, Joseph Steven Borbely, Melike Lakadamyali

50) Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes (Nature Methods) Sunday January 5th 2014
Thomas Thestrup, Julia Litzlbauer, Ingo Bartholom, Marsilius Mues, Luigi Russo, Hod Dana, Yuri Kovalchuk, Yajie Liang, Georgios Kalamakis, Yvonne Laukat, Stefan Becker, Gregor Witte, Anselm Geiger, Taylor Allen, Lawrence C Rome, Tsai-Wen Chen, Douglas S Kim, Olga Garaschuk, Christian Griesinger, Oliver Griesbeck

51) Optogenetic control of Drosophila using a red-shifted channelrhodopsin reveals experience-dependent influences on courtship (Nature Methods) Sunday December 22nd 2013
Hidehiko K Inagaki, Yonil Jung, Eric D Hoopfer, Allan M Wong, Neeli Mishra, John Y Lin, Roger Y Tsien, David J Anderson

52) Quantitative single-cell RNA-seq with unique molecular identifiers (Nature Methods) Sunday December 22nd 2013
Saiful Islam, Amit Zeisel, Simon Joost, Gioele La Manno, Pawel Zajac, Maria Kasper, Peter L, Sten Linnarsson

53) High-resolution mapping of transcription factor binding sites on native chromatin (Nature Methods) Sunday December 15th 2013
Sivakanthan Kasinathan, Guillermo A Orsi, Gabriel E Zentner, Kami Ahmad, Steven Henikoff

54) Drift time-specific collision energies enable deep-coverage data- independent acquisition proteomics (Nature Methods) Sunday December 15th 2013
Ute Distler, J, Pedro Navarro, Yishai Levin, Hansj, Stefan Tenzer

55) Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins (Nature Methods) Monday December 9th 2013
Jacob J Kennedy, Susan E Abbatiello, Kyunggon Kim, Ping Yan, Jeffrey R Whiteaker, Chenwei Lin, Jun Seok Kim, Yuzheng Zhang, Xianlong Wang, Richard G Ivey, Lei Zhao, Hophil Min, Youngju Lee, Myeong-Hee Yu, Eun Gyeong Yang, Cheolju Lee, Pei Wang, Henry Rodriguez, Youngsoo Kim, Steven A Carr, Amanda G Paulovich

56) A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles (Nature Methods) Sunday December 1st 2013
Chu Wang, Eranthie Weerapana, Megan M Blewett, Benjamin F Cravatt

57) Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny (Nature Methods) Sunday December 1st 2013
Xiaolei Yin, Henner F Farin, Johan H van Es, Hans Clevers, Robert Langer, Jeffrey M Karp

58) A quantitative liposome microarray to systematically characterize protein-lipid interactions (Nature Methods) Sunday November 24th 2013
Antoine-Emmanuel Saliba, Ivana Vonkova, Stefano Ceschia, Greg M Findlay, Kenji Maeda, Christian Tischer, Samy Deghou, Vera van Noort, Peer Bork, Tony Pawson, Jan Ellenberg, Anne-Claude Gavin

59) Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing (Nature Methods) Sunday November 24th 2013
Rui Zhang, Xin Li, Gokul Ramaswami, Kevin S Smith, Gustavo Turecki, Stephen B Montgomery, Jin Billy Li

60) A holidic medium for Drosophila melanogaster (Nature Methods) Sunday November 17th 2013
Matthew D W Piper, Eric Blanc, Ricardo Leit, Mingyao Yang, Xiaoli He, Nancy J Linford, Matthew P Hoddinott, Corinna Hopfen, George A Soultoukis, Christine Niemeyer, Fiona Kerr, Scott D Pletcher, Carlos Ribeiro, Linda Partridge

61) Integrating protein-protein interaction networks with phenotypes reveals signs of interactions (Nature Methods) Sunday November 17th 2013
Arunachalam Vinayagam, Jonathan Zirin, Charles Roesel, Yanhui Hu, Bahar Yilmazel, Anastasia A Samsonova, Ralph A Neum, Stephanie E Mohr, Norbert Perrimon

62) HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics (Nature Methods) Sunday November 17th 2013
Rui M M Branca, Lukas M Orre, Henrik J Johansson, Viktor Granholm, Mikael Huss, Åsa Pérez-Bercoff, Jenny Forshed, Lukas K, Janne Lehti

63) Deciphering laminar-specific neural inputs with line-scanning fMRI (Nature Methods) Sunday November 17th 2013
Xin Yu, Chunqi Qian, Der-yow Chen, Stephen J Dodd, Alan P Koretsky

64) Parallel measurement of dynamic changes in translation rates in single cells (Nature Methods) Sunday November 10th 2013
Kyuho Han, Ariel Jaimovich, Gautam Dey, Davide Ruggero, Oded Meyuhas, Nahum Sonenberg, Tobias Meyer

65) Quantifying the local resolution of cryo-EM density maps (Nature Methods) Sunday November 10th 2013
Alp Kucukelbir, Fred J Sigworth, Hemant D Tagare

66) Systematic evaluation of spliced alignment programs for RNA-seq data (Nature Methods) Sunday November 3rd 2013
P, Tamara Steijger, Botond Sipos, Gregory R Grant, Andr, Gunnar R, Nick Goldman, Tim J Hubbard, Jennifer Harrow, Roderic Guig, Paul Bertone

67) Assessment of transcript reconstruction methods for RNA-seq (Nature Methods) Sunday November 3rd 2013
Tamara Steijger, Josep F Abril, P, Felix Kokocinski, Tim J Hubbard, Roderic Guig, Jennifer Harrow, Paul Bertone

68) Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH (Nature Methods) Sunday November 3rd 2013
Jeff Vierstra, Hao Wang, Sam John, Richard Sandstrom, John A Stamatoyannopoulos

69) Accelerated discovery via a whole-cell model (Nature Methods) Sunday November 3rd 2013
Jayodita C Sanghvi, Sergi Regot, Silvia Carrasco, Jonathan R Karr, Miriam V Gutschow, Benjamin Bolival, Markus W Covert

70) Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system (Nature Methods) Sunday October 27th 2013
Ben C Collins, Ludovic C Gillet, George Rosenberger, Hannes L R, Anton Vichalkovski, Matthias Gstaiger, Ruedi Aebersold

71) Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition (Nature Methods) Sunday October 27th 2013
Jean-Philippe Lambert, Gordana Ivosev, Amber L Couzens, Brett Larsen, Mikko Taipale, Zhen-Yuan Lin, Quan Zhong, Susan Lindquist, Marc Vidal, Ruedi Aebersold, Tony Pawson, Ron Bonner, Stephen Tate, Anne-Claude Gingras

72) A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat (Nature Methods) Sunday October 27th 2013
Rita L Strack, Matthew D Disney, Samie R Jaffrey

73) Quantitative assessment of single-cell RNA-sequencing methods (Nature Methods) Sunday October 20th 2013
Angela R Wu, Norma F Neff, Tomer Kalisky, Piero Dalerba, Barbara Treutlein, Michael E Rothenberg, Francis M Mburu, Gary L Mantalas, Sopheak Sim, Michael F Clarke, Stephen R Quake

74) High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias (Nature Methods) Sunday October 20th 2013
Emanuel J P Nazareth, Joel E E Ostblom, Petra B L, Shreya Shukla, Manuel M Alvarez, Steve K W Oh, Ting Yin, Peter W Zandstra

75) Metagenomic species profiling using universal phylogenetic marker genes (Nature Methods) Sunday October 20th 2013
Shinichi Sunagawa, Daniel R Mende, Georg Zeller, Fernando Izquierdo-Carrasco, Simon A Berger, Jens Roat Kultima, Luis Pedro Coelho, Manimozhiyan Arumugam, Julien Tap, Henrik Bj, Simon Rasmussen, S, Oluf Pedersen, Francisco Guarner, Willem M de Vos, Jun Wang, Junhua Li, Jo, S Dusko Ehrlich, Alexandros Stamatakis, Peer Bork

76) Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells (Nature Methods) Sunday October 13th 2013
Shigeki Kiyonaka, Taketoshi Kajimoto, Reiko Sakaguchi, Daisuke Shinmi, Mariko Omatsu-Kanbe, Hiroshi Matsuura, Hiromi Imamura, Takenao Yoshizaki, Itaru Hamachi, Takashi Morii, Yasuo Mori

77) Formation of targeted monovalent quantum dots by steric exclusion (Nature Methods) Sunday October 13th 2013
Justin Farlow, Daeha Seo, Kyle E Broaders, Marcus J Taylor, Zev J Gartner, Young-wook Jun

78) DGIdb: mining the druggable genome (Nature Methods) Sunday October 13th 2013
Malachi Griffith, Obi L Griffith, Adam C Coffman, James V Weible, Josh F McMichael, Nicholas C Spies, James Koval, Indraniel Das, Matthew B Callaway, James M Eldred, Christopher A Miller, Janakiraman Subramanian, Ramaswamy Govindan, Runjun D Kumar, Ron Bose, Li Ding, Jason R Walker, David E Larson, David J Dooling, Scott M Smith, Timothy J Ley, Elaine R Mardis, Richard K Wilson

79) Detergent-free mass spectrometry of membrane protein complexes (Nature Methods) Sunday October 13th 2013
Jonathan T S Hopper, Yvonne Ting-Chun Yu, Dianfan Li, Alison Raymond, Mark Bostock, Idlir Liko, Victor Mikhailov, Arthur Laganowsky, Justin L P Benesch, Martin Caffrey, Daniel Nietlispach, Carol V Robinson

80) Image-based transcriptomics in thousands of single human cells at single-molecule resolution (Nature Methods) Sunday October 6th 2013
Nico Battich, Thomas Stoeger, Lucas Pelkmans

81) Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position (Nature Methods) Sunday October 6th 2013
Jason D Buenrostro, Paul G Giresi, Lisa C Zaba, Howard Y Chang, William J Greenleaf

82) Instant super-resolution imaging in live cells and embryos via analog image processing (Nature Methods) Sunday October 6th 2013
Andrew G York, Panagiotis Chandris, Damian Dalle Nogare, Jeffrey Head, Peter Wawrzusin, Robert S Fischer, Ajay Chitnis, Hari Shroff

83) Predicting functional gene interactions with the hierarchical interaction score (Nature Methods) Sunday October 6th 2013
Berend Snijder, Prisca Liberali, Mathieu Frechin, Thomas Stoeger, Lucas Pelkmans

84) Orthogonal Cas9 proteins for RNA-guided gene regulation and editing (Nature Methods) Sunday September 29th 2013
Kevin M Esvelt, Prashant Mali, Jonathan L Braff, Mark Moosburner, Stephanie J Yaung, George M Church

85) Improved low-resolution crystallographic refinement with Phenix and Rosetta (Nature Methods) Sunday September 29th 2013
Frank DiMaio, Nathaniel Echols, Jeffrey J Headd, Thomas C Terwilliger, Paul D Adams, David Baker

86) Differential abundance analysis for microbial marker-gene surveys (Nature Methods) Sunday September 29th 2013
Joseph N Paulson, O Colin Stine, H, Mihai Pop

87) eXtasy: variant prioritization by genomic data fusion (Nature Methods) Sunday September 29th 2013
Alejandro Sifrim, Dusan Popovic, Leon-Charles Tranchevent, Amin Ardeshirdavani, Ryo Sakai, Peter Konings, Joris R Vermeesch, Jan Aerts, Bart De Moor, Yves Moreau

88) Accounting for technical noise in single-cell RNA-seq experiments (Nature Methods) Sunday September 22nd 2013
Philip Brennecke, Simon Anders, Jong Kyoung Kim, Aleksandra A Ko, Xiuwei Zhang, Valentina Proserpio, Bianka Baying, Vladimir Benes, Sarah A Teichmann, John C Marioni, Marcus G Heisler

89) Smart-seq2 for sensitive full-length transcriptome profiling in single cells (Nature Methods) Sunday September 22nd 2013
Simone Picelli, Åsa K Björklund, Omid R Faridani, Sven Sagasser, G, Rickard Sandberg

90) Inducible control of gene expression with destabilized Cre (Nature Methods) Sunday September 22nd 2013
Richard Sando, Karsten Baumgaertel, Simon Pieraut, Nina Torabi-Rander, Thomas J Wandless, Mark Mayford, Anton Maximov

91) Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia (Nature Methods) Sunday September 22nd 2013
Steven Su, Siew Cheng Phua, Robert DeRose, Shuhei Chiba, Keishi Narita, Peter N Kalugin, Toshiaki Katada, Kenji Kontani, Sen Takeda, Takanari Inoue

92) TCPA: a resource for cancer functional proteomics data (Nature Methods) Sunday September 15th 2013
Jun Li, Yiling Lu, Rehan Akbani, Zhenlin Ju, Paul L Roebuck, Wenbin Liu, Ji-Yeon Yang, Bradley M Broom, Roeland G W Verhaak, David W Kane, Chris Wakefield, John N Weinstein, Gordon B Mills, Han Liang

93) Network-based stratification of tumor mutations (Nature Methods) Sunday September 15th 2013
Matan Hofree, John P Shen, Hannah Carter, Andrew Gross, Trey Ideker

94) IntOGen-mutations identifies cancer drivers across tumor types (Nature Methods) Sunday September 15th 2013
Abel Gonzalez-Perez, Christian Perez-Llamas, Jordi Deu-Pons, David Tamborero, Michael P Schroeder, Alba Jene-Sanz, Alberto Santos, Nuria Lopez-Bigas

95) Exploiting tertiary structure through local folds for crystallographic phasing (Nature Methods) Sunday September 15th 2013
Massimo Sammito, Claudia Mill, Dayt, I, Kathrin Meindl, Ivan De Marino, Giovanna Petrillo, Rub, Jos, Kornelius Zeth, George M Sheldrick, Isabel Us

96) Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light (Nature Methods) Sunday September 8th 2013
Tina Schr, Robert Prevedel, Karin Aumayr, Manuel Zimmer, Alipasha Vaziri

97) Solid-state NMR spectroscopy structure determination of a lipid-embedded heptahelical membrane protein (Nature Methods) Sunday September 8th 2013
Shenlin Wang, Rachel A Munro, Lichi Shi, Izuru Kawamura, Takashi Okitsu, Akimori Wada, So-Young Kim, Kwang-Hwan Jung, Leonid S Brown, Vladimir Ladizhansky

98) Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination (Nature Methods) Sunday September 1st 2013
Daniel J Dickinson, Jordan D Ward, David J Reiner, Bob Goldstein

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