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1) High-throughput tetrad analysis (Nature Methods) Sunday May 12th 2013
Catherine L Ludlow, Adrian C Scott, Gareth A Cromie, Eric W Jeffery, Amy Sirr, Patrick May, Jake Lin, Teresa L Gilbert, Michelle Hays, Aim

2) The Caenorhabditis elegans Lifespan Machine (Nature Methods) Sunday May 12th 2013
Nicholas Stroustrup, Bryne E Ulmschneider, Zachary M Nash, Isaac F L, Javier Apfeld, Walter Fontana

3) Improved tools for the Brainbow toolbox (Nature Methods) Sunday May 5th 2013
Dawen Cai, Kimberly B Cohen, Tuanlian Luo, Jeff W Lichtman, Joshua R Sanes

4) Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data (Nature Methods) Sunday May 5th 2013
Chen-Shan Chin, David H Alexander, Patrick Marks, Aaron A Klammer, James Drake, Cheryl Heiner, Alicia Clum, Alex Copeland, John Huddleston, Evan E Eichler, Stephen W Turner, Jonas Korlach

5) Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM (Nature Methods) Sunday May 5th 2013
Xueming Li, Paul Mooney, Shawn Zheng, Christopher R Booth, Michael B Braunfeld, Sander Gubbens, David A Agard, Yifan Cheng

6) Live mammalian cell arrays (Nature Methods) Sunday May 5th 2013
Kristina Woodruff, Luis M Fidalgo, Samy Gobaa, Matthias P Lutolf, Sebastian J Maerkl

7) Comprehensive macromolecular conformations mapped by quantitative SAXS analyses (Nature Methods) Sunday April 28th 2013
Greg L Hura, Helen Budworth, Kevin N Dyer, Robert P Rambo, Michal Hammel, Cynthia T McMurray, John A Tainer

8) Measuring image resolution in optical nanoscopy (Nature Methods) Sunday April 28th 2013
Robert P J Nieuwenhuizen, Keith A Lidke, Mark Bates, Daniela Leyton Puig, David Gr, Sjoerd Stallinga, Bernd Rieger

9) Gene-pair expression signatures reveal lineage control (Nature Methods) Sunday April 21st 2013
Merja Hein, Matti Nykter, Roger Kramer, Anke Wienecke-Baldacchino, Lasse Sinkkonen, Joseph Xu Zhou, Richard Kreisberg, Stuart A Kauffman, Sui Huang, Ilya Shmulevich

10) Absolute quantification of transcription factors during cellular differentiation using multiplexed targeted proteomics (Nature Methods) Sunday April 14th 2013
Jovan Simicevic, Adrien W Schmid, Paola A Gilardoni, Benjamin Zoller, Sunil K Raghav, Irina Krier, Carine Gubelmann, Fr, Felix Naef, Marc Moniatte, Bart Deplancke

11) A simple tool to improve pluripotent stem cell differentiation (Nature Methods) Sunday April 14th 2013
Sundari Chetty, Felicia Walton Pagliuca, Christian Honore, Anastasie Kweudjeu, Alireza Rezania, Douglas A Melton

12) Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping (Nature Methods) Sunday April 7th 2013
Christina Laufer, Bernd Fischer, Maximilian Billmann, Wolfgang Huber, Michael Boutros

13) Adhesion strength (Nature Methods) Sunday April 7th 2013
Ankur Singh, Shalu Suri, Ted Lee, Jamie M Chilton, Marissa T Cooke, Weiqiang Chen, Jianping Fu, Steven L Stice, Hang Lu, Todd C McDevitt, Andr

14) Direct transfer of whole genomes from bacteria to yeast (Nature Methods) Sunday March 31st 2013
Bogumil J Karas, Jelena Jablanovic, Lijie Sun, Li Ma, Gregory M Goldgof, Jason Stam, Adi Ramon, Micah J Manary, Elizabeth A Winzeler, J, Philip D Weyman, Daniel G Gibson, John I Glass, Clyde A Hutchison, Hamilton O Smith, Yo Suzuki

15) Single-molecule imaging of transcription factor binding to DNA in live mammalian cells (Nature Methods) Monday March 25th 2013
J Christof M Gebhardt, David M Suter, Rahul Roy, Ziqing W Zhao, Alec R Chapman, Srinjan Basu, Tom Maniatis, X Sunney Xie

16) Whole-brain functional imaging at cellular resolution using light-sheet microscopy (Nature Methods) Monday March 25th 2013
Misha B Ahrens, Philipp J Keller

17) A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum (Nature Methods) Monday March 25th 2013
Nathan C Shaner, Gerard G Lambert, Andrew Chammas, Yuhui Ni, Paula J Cranfill, Michelle A Baird, Brittney R Sell, John R Allen, Richard N Day, Maria Israelsson, Michael W Davidson, Jiwu Wang

18) Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing (Nature Methods) Sunday March 17th 2013
Nicola Crosetto, Abhishek Mitra, Maria Joao Silva, Magda Bienko, Norbert Dojer, Qi Wang, Elif Karaca, Roberto Chiarle, Magdalena Skrzypczak, Krzysztof Ginalski, Philippe Pasero, Maga Rowicka, Ivan Dikic

19) Barcoding cells using cell-surface programmable DNA-binding domains (Nature Methods) Sunday March 17th 2013
Prashant Mali, John Aach, Je-Hyuk Lee, Daniel Levner, Lisa Nip, George M Church

20) Quantitative estimation of activity and quality for collections of functional genetic elements (Nature Methods) Sunday March 10th 2013
Vivek K Mutalik, Joao C Guimaraes, Guillaume Cambray, Quynh-Anh Mai, Marc Juul Christoffersen, Lance Martin, Ayumi Yu, Colin Lam, Cesar Rodriguez, Gaymon Bennett, Jay D Keasling, Drew Endy, Adam P Arkin

21) Precise and reliable gene expression via standard transcription and translation initiation elements (Nature Methods) Sunday March 10th 2013
Vivek K Mutalik, Joao C Guimaraes, Guillaume Cambray, Colin Lam, Marc Juul Christoffersen, Quynh-Anh Mai, Andrew B Tran, Morgan Paull, Jay D Keasling, Adam P Arkin, Drew Endy

22) QuaNCAT: quantitating proteome dynamics in primary cells (Nature Methods) Sunday March 10th 2013
Andrew J M Howden, Vincent Geoghegan, Kristin Katsch, Georgios Efstathiou, Bhaskar Bhushan, Omar Boutureira, Benjamin Thomas, David C Trudgian, Benedikt M Kessler, Daniela C Dieterich, Benjamin G Davis, Oreste Acuto

23) Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS (Nature Methods) Sunday March 3rd 2013
Markku Varjosalo, Roberto Sacco, Alexey Stukalov, Audrey van Drogen, Melanie Planyavsky, Simon Hauri, Ruedi Aebersold, Keiryn L Bennett, Jacques Colinge, Matthias Gstaiger, Giulio Superti-Furga

24) Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells (Nature Methods) Sunday March 3rd 2013
Charlotte Stadler, Elton Rexhepaj, Vasanth R Singan, Robert F Murphy, Rainer Pepperkok, Mathias Uhl, Jeremy C Simpson, Emma Lundberg

25) Ultrahigh accuracy imaging modality for super-localization microscopy (Nature Methods) Sunday March 3rd 2013
Jerry Chao, Sripad Ram, E Sally Ward, Raimund J Ober

26) A Y2H-seq approach defines the human protein methyltransferase interactome (Nature Methods) Sunday March 3rd 2013
Mareike Weimann, Arndt Grossmann, Jonathan Woodsmith, Ziya, Petra Birth, David Meierhofer, Nouhad Benlasfer, Taras Valovka, Bernd Timmermann, Erich E Wanker, Sascha Sauer, Ulrich Stelzl

27) Predicting the molecular complexity of sequencing libraries (Nature Methods) Sunday March 3rd 2013
Timothy Daley, Andrew D Smith

28) Neutron-encoded mass signatures for multiplexed proteome quantification (Nature Methods) Sunday March 3rd 2013
Alexander S Hebert, Anna E Merrill, Derek J Bailey, Amelia J Still, Michael S Westphall, Eric R Strieter, David J Pagliarini, Joshua J Coon

29) TALEN-mediated precise genome modification by homologous recombination in zebrafish (Nature Methods) Sunday March 3rd 2013
Yao Zu, Xiangjun Tong, Zhanxiang Wang, Da Liu, Ruochuan Pan, Zhe Li, Yingying Hu, Zhou Luo, Peng Huang, Qian Wu, Zuoyan Zhu, Bo Zhang, Shuo Lin

30) Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation (Nature Methods) Sunday February 17th 2013
Marshall J Levesque, Arjun Raj

31) Quantitative genetic-interaction mapping in mammalian cells (Nature Methods) Wednesday February 13th 2013
Assen Roguev, Dale Talbot, Gian Luca Negri, Michael Shales, Gerard Cagney, Sourav Bandyopadhyay, Barbara Panning, Nevan J Krogan

32) Critical assessment of automated flow cytometry data analysis techniques (Nature Methods) Sunday February 10th 2013
Nima Aghaeepour, Greg Finak, Holger Hoos, Tim R Mosmann, Ryan Brinkman, Raphael Gottardo, Richard H Scheuermann

33) TALENs and ZFNs are associated with different mutation signatures (Nature Methods) Sunday February 10th 2013
Yongsub Kim, Jiyeon Kweon, Jin-Soo Kim

34) Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells (Nature Methods) Sunday February 10th 2013
Jonathan J Hulce, Armand B Cognetta, Micah J Niphakis, Sarah E Tully, Benjamin F Cravatt

35) Extracting intracellular diffusive states and transition rates from single-molecule tracking data (Nature Methods) Sunday February 10th 2013
Fredrik Persson, Martin Lind, Cecilia Unoson, Johan Elf

36) Robust, synergistic regulation of human gene expression using TALE activators (Nature Methods) Sunday February 10th 2013
Morgan L Maeder, Samantha J Linder, Deepak Reyon, James F Angstman, Yanfang Fu, Jeffry D Sander, J Keith Joung

37) Optogenetic protein clustering and signaling activation in mammalian cells (Nature Methods) Sunday February 3rd 2013
Lukasz J Bugaj, Atri T Choksi, Colin K Mesuda, Ravi S Kane, David V Schaffer

38) Generating parabiotic zebrafish embryos for cell migration and homing studies (Nature Methods) Sunday February 3rd 2013
Doris Lou Demy, Zachary Ranta, Jean-Michel Giorgi, Magali Gonzalez, Philippe Herbomel, Karima Kissa

39) Synergistic and tunable human gene activation by combinations of synthetic transcription factors (Nature Methods) Sunday February 3rd 2013
Pablo Perez-Pinera, David G Ousterout, Jonathan M Brunger, Alicia M Farin, Katherine A Glass, Farshid Guilak, Gregory E Crawford, Alexander J Hartemink, Charles A Gersbach

40) A large-scale evaluation of computational protein function prediction (Nature Methods) Sunday January 27th 2013
Predrag Radivojac, Wyatt T Clark, Tal Ronnen Oron, Alexandra M Schnoes, Tobias Wittkop, Artem Sokolov, Kiley Graim, Christopher Funk, Karin Verspoor, Asa Ben-Hur, Gaurav Pandey, Jeffrey M Yunes, Ameet S Talwalkar, Susanna Repo, Michael L Souza, Damiano Piovesan, Rita Casadio, Zheng Wang, Jianlin Cheng, Hai Fang, Julian Gough, Patrik Koskinen, Petri T, Jussi Nokso-Koivisto, Liisa Holm, Domenico Cozzetto, Daniel W A Buchan, Kevin Bryson, David T Jones, Bhakti Limaye, Harshal Inamdar, Avik Datta, Sunitha K Manjari, Rajendra Joshi, Meghana Chitale, Daisuke Kihara, Andreas M Lisewski, Serkan Erdin, Eric Venner, Olivier Lichtarge, Robert Rentzsch, Haixuan Yang, Alfonso E Romero, Prajwal Bhat, Alberto Paccanaro, Tobias Hamp, Rebecca Ka, Stefan Seemayer, Esmeralda Vicedo, Christian Schaefer, Dominik Achten, Florian Auer, Ariane Boehm, Tatjana Braun, Maximilian Hecht, Mark Heron, Peter H, Thomas A Hopf, Stefanie Kaufmann, Michael Kiening, Denis Krompass, Cedric Landerer, Yannick Mahlich, Manfred Roos, Jari Bj, Tapio Salakoski, Andrew Wong, Hagit Shatkay, Fanny Gatzmann, Ingolf Sommer, Mark N Wass, Michael J E Sternberg, Nives, Fran Supek, Matko Bo, Pan, Sa, Tomislav, Yiannis A I Kourmpetis, Aalt D J van Dijk, Cajo J F ter Braak, Yuanpeng Zhou, Qingtian Gong, Xinran Dong, Weidong Tian, Marco Falda, Paolo Fontana, Enrico Lavezzo, Barbara Di Camillo, Stefano Toppo, Liang Lan, Nemanja Djuric, Yuhong Guo, Slobodan Vucetic, Amos Bairoch, Michal Linial, Patricia C Babbitt, Steven E Brenner, Christine Orengo, Burkhard Rost, Sean D Mooney, Iddo Friedberg

41) A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets (Nature Methods) Sunday January 20th 2013
Mohsen Khorshid, Jean Hausser, Mihaela Zavolan, Erik van Nimwegen

42) Detection of histone modifications at specific gene loci in single cells in histological sections (Nature Methods) Sunday January 13th 2013
Delphine Gomez, Laura S Shankman, Anh T Nguyen, Gary K Owens

43) An optimized fluorescent probe for visualizing glutamate neurotransmission (Nature Methods) Sunday January 13th 2013
Jonathan S Marvin, Bart G Borghuis, Lin Tian, Joseph Cichon, Mark T Harnett, Jasper Akerboom, Andrew Gordus, Sabine L Renninger, Tsai-Wen Chen, Cornelia I Bargmann, Michael B Orger, Eric R Schreiter, Jonathan B Demb, Wen-Biao Gan, S Andrew Hires, Loren L Looger

44) Lentiviral vector (Nature Methods) Sunday January 13th 2013
Marco Ranzani, Daniela Cesana, Cynthia C Bartholomae, Francesca Sanvito, Mauro Pala, Fabrizio Benedicenti, Pierangela Gallina, Lucia Sergi Sergi, Stefania Merella, Alessandro Bulfone, Claudio Doglioni, Christof von Kalle, Yoon Jun Kim, Manfred Schmidt, Giovanni Tonon, Luigi Naldini, Eugenio Montini

45) iGLuc: a luciferase-based inflammasome and protease activity reporter (Nature Methods) Sunday January 6th 2013
Eva Bartok, Franz Bauernfeind, Maria G Khaminets, Christopher Jakobs, Brian Monks, Katherine A Fitzgerald, Eicke Latz, Veit Hornung

46) A pharmacological organization of G protein (Nature Methods) Sunday January 6th 2013
Henry Lin, Maria F Sassano, Bryan L Roth, Brian K Shoichet

47) Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms (Nature Methods) Sunday December 23rd 2012
Nicole Andenmatten, Saskia Egarter, Allison J Jackson, Nicolas Jullien, Jean-Paul Herman, Markus Meissner

48) A versatile genome-scale PCR-based pipeline for high-definition DNA FISH (Nature Methods) Sunday December 23rd 2012
Magda Bienko, Nicola Crosetto, Leonid Teytelman, Sandy Klemm, Shalev Itzkovitz, Alexander van Oudenaarden

49) Single-molecule analysis of gene expression using two-color RNA labeling in live yeast (Nature Methods) Sunday December 23rd 2012
Sami Hocine, Pascal Raymond, Daniel Zenklusen, Jeffrey A Chao, Robert H Singer

50) Interactome3D: adding structural details to protein networks (Nature Methods) Sunday December 16th 2012
Roberto Mosca, Arnaud C, Patrick Aloy

51) Analysis of alternative cleavage and polyadenylation by 3 (Nature Methods) Sunday December 16th 2012
Mainul Hoque, Zhe Ji, Dinghai Zheng, Wenting Luo, Wencheng Li, Bei You, Ji Yeon Park, Ghassan Yehia, Bin Tian

52) Quantitative optical trapping on single organelles in cell extract (Nature Methods) Sunday December 16th 2012
Pradeep Barak, Ashim Rai, Priyanka Rai, Roop Mallik

53) Generation of integration-free neural progenitor cells from cells in human urine (Nature Methods) Sunday December 9th 2012
Lihui Wang, Linli Wang, Wenhao Huang, Huanxing Su, Yanting Xue, Zhenghui Su, Baojian Liao, Haitao Wang, Xichen Bao, Dajiang Qin, Jufang He, Wutian Wu, Kwok Fai So, Guangjin Pan, Duanqing Pei

54) Fast multicolor 3D imaging using aberration-corrected multifocus microscopy (Nature Methods) Sunday December 9th 2012
Sara Abrahamsson, Jiji Chen, Bassam Hajj, Sjoerd Stallinga, Alexander Y Katsov, Jan Wisniewski, Gaku Mizuguchi, Pierre Soule, Florian Mueller, Claire Dugast Darzacq, Xavier Darzacq, Carl Wu, Cornelia I Bargmann, David A Agard, Maxime Dahan, Mats G L Gustafsson

55) Conversion of human fibroblasts to angioblast-like progenitor cells (Nature Methods) Sunday December 2nd 2012
Leo Kurian, Ignacio Sancho-Martinez, Emmanuel Nivet, Aitor Aguirre, Krystal Moon, Caroline Pendaries, Cecile Volle-Challier, Francoise Bono, Jean-Marc Herbert, Julian Pulecio, Yun Xia, Mo Li, Nuria Montserrat, Sergio Ruiz, Ilir Dubova, Concepcion Rodriguez, Ahmet M Denli, Francesca S Boscolo, Rathi D Thiagarajan, Fred H Gage, Jeanne F Loring, Louise C Laurent, Juan Carlos Izpisua Belmonte

56) Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing (Nature Methods) Sunday December 2nd 2012
Nicholas A Bokulich, Sathish Subramanian, Jeremiah J Faith, Dirk Gevers, Jeffrey I Gordon, Rob Knight, David A Mills, J Gregory Caporaso

57) Correcting pervasive errors in RNA crystallography through enumerative structure prediction (Nature Methods) Sunday December 2nd 2012
Fang-Chieh Chou, Parin Sripakdeevong, Sergey M Dibrov, Thomas Hermann, Rhiju Das

58) JAABA: interactive machine learning for automatic annotation of animal behavior (Nature Methods) Sunday December 2nd 2012
Mayank Kabra, Alice A Robie, Marta Rivera-Alba, Steven Branson, Kristin Branson

59) Digestion and depletion of abundant proteins improves proteomic coverage (Nature Methods) Sunday December 2nd 2012
Bryan R Fonslow, Benjamin D Stein, Kristofor J Webb, Tao Xu, Jeong Choi, Sung Kyu Park, John R Yates

60) Streaming fragment assignment for real-time analysis of sequencing experiments (Nature Methods) Sunday December 2nd 2012
Adam Roberts, Lior Pachter

61) Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation (Nature Methods) Sunday November 11th 2012
Rohit Prakash, Ofer Yizhar, Benjamin Grewe, Charu Ramakrishnan, Nancy Wang, Inbal Goshen, Adam M Packer, Darcy S Peterka, Rafael Yuste, Mark J Schnitzer, Karl Deisseroth

62) De novo derivation of proteomes from transcriptomes for transcript and protein identification (Nature Methods) Sunday November 11th 2012
Vanessa C Evans, Gary Barker, Kate J Heesom, Jun Fan, Conrad Bessant, David A Matthews

63) A toolkit and benchmark study for FRET-restrained high-precision structural modeling (Nature Methods) Sunday November 11th 2012
Stanislav Kalinin, Thomas Peulen, Simon Sindbert, Paul J Rothwell, Sylvia Berger, Tobias Restle, Roger S Goody, Holger Gohlke, Claus A M Seidel

64) Membrane-protein structure determination by solid-state NMR spectroscopy of microcrystals (Nature Methods) Sunday November 11th 2012
Shakeel Ahmad Shahid, Benjamin Bardiaux, W Trent Franks, Ludwig Krabben, Michael Habeck, Barth-Jan van Rossum, Dirk Linke

65) Systematic reconstruction of RNA functional motifs with high-throughput microfluidics (Nature Methods) Sunday November 11th 2012
Lance Martin, Matthias Meier, Shawn M Lyons, Rene V Sit, William F Marzluff, Stephen R Quake, Howard Y Chang

66) Two-photon optogenetics of dendritic spines and neural circuits (Nature Methods) Sunday November 11th 2012
Adam M Packer, Darcy S Peterka, Jan J Hirtz, Rohit Prakash, Karl Deisseroth, Rafael Yuste

67) Phase-gradient microscopy in thick tissue with oblique back-illumination (Nature Methods) Sunday October 28th 2012
Tim N Ford, Kengyeh K Chu, Jerome Mertz

68) The GEM mapper: fast, accurate and versatile alignment by filtration (Nature Methods) Sunday October 28th 2012
Santiago Marco-Sola, Michael Sammeth, Roderic Guig, Paolo Ribeca

69) Ultrabright photoactivatable fluorophores created by reductive caging (Nature Methods) Sunday October 28th 2012
Joshua C Vaughan, Shu Jia, Xiaowei Zhuang

70) Staining and embedding the whole mouse brain for electron microscopy (Nature Methods) Sunday October 21st 2012
Shawn Mikula, Jonas Binding, Winfried Denk

71) Membrane-protein binding measured with solution-phase plasmonic nanocube sensors (Nature Methods) Sunday October 21st 2012
Hung-Jen Wu, Joel Henzie, Wan-Chen Lin, Christopher Rhodes, Zhu Li, Elodie Sartorel, Jeremy Thorner, Peidong Yang, Jay T Groves

72) Imputing gene expression from selectively reduced probe sets (Nature Methods) Sunday October 14th 2012
Yoni Donner, Ting Feng, Christophe Benoist, Daphne Koller

73) Magnetic nanoparticle (Nature Methods) Sunday October 14th 2012
Peter Tseng, Jack W Judy, Dino Di Carlo

74) Automated velocity mapping of migrating cell populations (AVeMap) (Nature Methods) Sunday October 14th 2012
Maxime Deforet, Maria Carla Parrini, Laurence Petitjean, Marco Biondini, Axel Buguin, Jacques Camonis, Pascal Silberzan

75) High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies (Nature Methods) Sunday October 14th 2012
Rebecca J Rose, Eugen Damoc, Eduard Denisov, Alexander Makarov, Albert J R Heck

76) DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution (Nature Methods) Sunday October 7th 2012
Ester Falconer, Mark Hills, Ulrike Naumann, Steven S S Poon, Elizabeth A Chavez, Ashley D Sanders, Yongjun Zhao, Martin Hirst, Peter M Lansdorp

77) Iterative plug-and-play methodology for constructing and modifying synthetic gene networks (Nature Methods) Sunday October 7th 2012
Kevin D Litcofsky, Raffi B Afeyan, Russell J Krom, Ahmad S Khalil, James J Collins

78) A microfluidic device and computational platform for high-throughput live imaging of gene expression (Nature Methods) Sunday September 30th 2012
Wolfgang Busch, Brad T Moore, Bradley Martsberger, Daniel L Mace, Richard W Twigg, Jee Jung, Iulian Pruteanu-Malinici, Scott J Kennedy, Gregory K Fricke, Robert L Clark, Uwe Ohler, Philip N Benfey

79) An adaptor from translational to transcriptional control enables predictable assembly of complex regulation (Nature Methods) Sunday September 30th 2012
Chang C Liu, Lei Qi, Julius B Lucks, Thomas H Segall-Shapiro, Denise Wang, Vivek K Mutalik, Adam P Arkin

80) TGF (Nature Methods) Sunday September 16th 2012
Asuka Inoue, Jun Ishiguro, Hajime Kitamura, Naoaki Arima, Michiyo Okutani, Akira Shuto, Shigeki Higashiyama, Tomohiko Ohwada, Hiroyuki Arai, Kumiko Makide, Junken Aoki

81) Reversible labeling of native and fusion-protein motifs (Nature Methods) Sunday September 16th 2012
Nicolas M Kosa, Robert W Haushalter, Andrew R Smith, Michael D Burkart

82) Improving FRET dynamic range with bright green and red fluorescent proteins (Nature Methods) Sunday September 9th 2012
Amy J Lam, Fran, Yiyang Gong, Jesse D Marshall, Paula J Cranfill, Michelle A Baird, Michael R McKeown, J, Michael W Davidson, Mark J Schnitzer, Roger Y Tsien, Michael Z Lin

83) A general approach to break the concentration barrier in single-molecule imaging (Nature Methods) Sunday September 9th 2012
Anna B Loveland, Satoshi Habuchi, Johannes C Walter, Antoine M van Oijen

84) Robust 4C-seq data analysis to screen for regulatory DNA interactions (Nature Methods) Sunday September 9th 2012
Harmen J G van de Werken, Gilad Landan, Sjoerd J B Holwerda, Michael Hoichman, Petra Klous, Ran Chachik, Erik Splinter, Christian Valdes Quezada, Yuva, Britta A M Bouwman, Marjon J A M Verstegen, Elzo de Wit, Amos Tanay, Wouter de Laat

85) Coupling endonucleases with DNA end (Nature Methods) Sunday September 2nd 2012
Michael T Certo, Kamila S Gwiazda, Ryan Kuhar, Blythe Sather, Gabrielle Curinga, Tyler Mandt, Michelle Brault, Abigail R Lambert, Sarah K Baxter, Kyle Jacoby, Byoung Y Ryu, Hans-Peter Kiem, Agnes Gouble, Frederic Paques, David J Rawlings, Andrew M Scharenberg

86) Ultrafast force-clamp spectroscopy of single molecules reveals load dependence of myosin working stroke (Nature Methods) Wednesday August 29th 2012
Marco Capitanio, Monica Canepari, Manuela Maffei, Diego Beneventi, Carina Monico, Francesco Vanzi, Roberto Bottinelli, Francesco Saverio Pavone

87) Iterative correction of Hi-C data reveals hallmarks of chromosome organization (Nature Methods) Wednesday August 29th 2012
Maxim Imakaev, Geoffrey Fudenberg, Rachel Patton McCord, Natalia Naumova, Anton Goloborodko, Bryan R Lajoie, Job Dekker, Leonid A Mirny

88) Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases (Nature Methods) Sunday August 26th 2012
Judith Straimer, Marcus C S Lee, Andrew H Lee, Bryan Zeitler, April E Williams, Jocelynn R Pearl, Lei Zhang, Edward J Rebar, Philip D Gregory, Manuel Llin, Fyodor D Urnov, David A Fidock

89) Autonomous screening of C. elegans identifies genes implicated in synaptogenesis (Nature Methods) Sunday August 19th 2012
Matthew M Crane, Jeffrey N Stirman, Chan-Yen Ou, Peri T Kurshan, James M Rehg, Kang Shen, Hang Lu

90) Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data (Nature Methods) Sunday August 12th 2012
Darren R Tyson, Shawn P Garbett, Peter L Frick, Vito Quaranta

91) Accurate gene synthesis with tag-directed retrieval of sequence-verified DNA molecules (Nature Methods) Sunday August 12th 2012
Jerrod J Schwartz, Choli Lee, Jay Shendure

92) A high-throughput approach for measuring temporal changes in the interactome (Nature Methods) Sunday August 5th 2012
Anders R Kristensen, Joerg Gsponer, Leonard J Foster

93) A mouse model to identify cooperating signaling pathways in cancer (Nature Methods) Sunday August 5th 2012
Monica Musteanu, Leander Blaas, Rainer Zenz, Jasmin Svinka, Thomas Hoffmann, Beatrice Grabner, Daniel Schramek, Hans-Peter Kantner, Mathias M, Thomas Kolbe, Thomas R, Richard Moriggl, Lukas Kenner, Dagmar Stoiber, Josef Martin Penninger, Helmut Popper, Emilio Casanova, Robert Eferl

94) Direct observation of mammalian cell growth and size regulation (Nature Methods) Sunday August 5th 2012
Sungmin Son, Amit Tzur, Yaochung Weng, Paul Jorgensen, Jisoo Kim, Marc W Kirschner, Scott R Manalis

95) Prevention of overfitting in cryo-EM structure determination (Nature Methods) Sunday July 29th 2012
Sjors H W Scheres, Shaoxia Chen

96) Wisdom of crowds for robust gene network inference (Nature Methods) Sunday July 15th 2012
Daniel Marbach, James C Costello, Robert Küffner, Nicole M Vega, Robert J Prill, Diogo M Camacho, Kyle R Allison, Manolis Kellis, James J Collins, Gustavo Stolovitzky

97) A culture system to study oligodendrocyte myelination processes using engineered nanofibers (Nature Methods) Sunday July 15th 2012
Seonok Lee, Michelle K Leach, Stephanie A Redmond, S Y Christin Chong, Synthia H Mellon, Samuel J Tuck, Zhang-Qi Feng, Joseph M Corey, Jonah R Chan

98) The Metatron: an experimental system to study dispersal and metaecosystems for terrestrial organisms (Nature Methods) Sunday July 15th 2012
Delphine Legrand, Olivier Guillaume, Michel Baguette, Julien Cote, Audrey Trochet, Olivier Calvez, Susanne Zajitschek, Felix Zajitschek, Jane Lecomte, Quentin Bénard, Jean-François Le Galliard, Jean Clobert

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