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1) Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies (Nature Medicine) Monday June 29th 2015
Judy H Cho, Marc Feldman

2) Inflammasomes: mechanism of action, role in disease, and therapeutics (Nature Medicine) Monday June 29th 2015
Haitao Guo, Justin B Callaway, Jenny P-Y Ting

3) The emerging role of resident memory T cells in protective immunity and inflammatory disease (Nature Medicine) Monday June 29th 2015
Chang Ook Park, Thomas S Kupper

4) Innate lymphoid cells in the initiation, regulation and resolution of inflammation (Nature Medicine) Monday June 29th 2015
Gregory F Sonnenberg, David Artis

5) IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases (Nature Medicine) Monday June 29th 2015
Michele W L Teng, Edward P Bowman, Joshua J McElwee, Mark J Smyth, Jean-Laurent Casanova, Andrea M Cooper, Daniel J Cua

6) Influence of nutrient-derived metabolites on lymphocyte immunity (Nature Medicine) Monday June 29th 2015
Marc Veldhoen, Cristina Ferreira

7) A gut feeling about immunity (Nature Medicine) Monday June 29th 2015
Roxanne Khamsi

8) Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt (Nature Medicine) Wednesday June 24th 2015
Justin E Wilson, Alex S Petrucelli, Liang Chen, A Alicia Koblansky, Agnieszka D Truax, Yoshitaka Oyama, Arlin B Rogers, W June Brickey, Yuli Wang, Monika Schneider, Marcus M, Wei-Chun Chou, Brianne R Barker, Christian Jobin, Nancy L Allbritton, Dale A Ramsden, Beckley K Davis, Jenny P Y Ting

9) Subclonal diversification of primary breast cancer revealed by multiregion sequencing (Nature Medicine) Monday June 22nd 2015
Lucy R Yates, Moritz Gerstung, Stian Knappskog, Christine Desmedt, Gunes Gundem, Peter Van Loo, Turid Aas, Ludmil B Alexandrov, Denis Larsimont, Helen Davies, Yilong Li, Young Seok Ju, Manasa Ramakrishna, Hans Kristian Haugland, Peer Kaare Lilleng, Serena Nik-Zainal, Stuart McLaren, Adam Butler, Sancha Martin, Dominic Glodzik, Andrew Menzies, Keiran Raine, Jonathan Hinton, David Jones, Laura J Mudie, Bing Jiang, Delphine Vincent, April Greene-Colozzi, Pierre-Yves Adnet, Aquila Fatima, Marion Maetens, Michail Ignatiadis, Michael R Stratton, Christos Sotiriou, Andrea L Richardson, Per Eystein L, David C Wedge, Peter J Campbell

10) Inhibition of amyloid- (Nature Medicine) Monday June 22nd 2015
Teresa Bachhuber, Natalie Katzmarski, Joanna F McCarter, Desiree Loreth, Sabina Tahirovic, Frits Kamp, Claudia Abou-Ajram, Brigitte Nuscher, Alberto Serrano-Pozo, Alexandra M, Marco Prinz, Harald Steiner, Bradley T Hyman, Christian Haass, Melanie Meyer-Luehmann

11) Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter (Nature Medicine) Monday June 22nd 2015
Jing Wang, Chongxiu Sun, Norbert Gerdes, Conglin Liu, Mengyang Liao, Jian Liu, Michael A Shi, Aina He, Yi Zhou, Galina K Sukhova, Huimei Chen, Xian Wu Cheng, Masafumi Kuzuya, Toyoaki Murohara, Jie Zhang, Xiang Cheng, Mengmeng Jiang, Gary E Shull, Shaunessy Rogers, Chao-Ling Yang, Qiang Ke, Sabina Jelen, Ren, David H Ellison, Petr Jarolim, Peter Libby, Guo-Ping Shi

12) Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension (Nature Medicine) Monday June 15th 2015
Lu Long, Mark L Ormiston, Xudong Yang, Mark Southwood, Stefan Gr, Rajiv D Machado, Matthias Mueller, Bernd Kinzel, Lai Ming Yung, Janine M Wilkinson, Stephen D Moore, Kylie M Drake, Micheala A Aldred, Paul B Yu, Paul D Upton, Nicholas W Morrell

13) Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion (Nature Medicine) Monday June 15th 2015
Talitha van der Meulen, Cynthia J Donaldson, Elena C, Anna E Hunter, Christopher Cowing-Zitron, Lynley D Pound, Michael W Adams, Andreas Zembrzycki, Kevin L Grove, Mark O Huising

14) Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes (Nature Medicine) Monday June 15th 2015
Ruidan Xue, Matthew D Lynes, Jonathan M Dreyfuss, Farnaz Shamsi, Tim J Schulz, Hongbin Zhang, Tian Lian Huang, Kristy L Townsend, Yiming Li, Hirokazu Takahashi, Lauren S Weiner, Andrew P White, Maureen S Lynes, Lee L Rubin, Laurie J Goodyear, Aaron M Cypess, Yu-Hua Tseng

15) Diabetes primes neutrophils to undergo NETosis, which impairs wound healing (Nature Medicine) Monday June 15th 2015
Siu Ling Wong, Melanie Demers, Kimberly Martinod, Maureen Gallant, Yanming Wang, Allison B Goldfine, C Ronald Kahn, Denisa D Wagner

16) Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors (Nature Medicine) Monday June 8th 2015
Dario R Lemos, Farshad Babaeijandaghi, Marcela Low, Chih-Kai Chang, Sunny T Lee, Daniela Fiore, Regan-Heng Zhang, Anuradha Natarajan, Sergei A Nedospasov, Fabio M V Rossi

17) Activation of HIF-1 (Nature Medicine) Monday June 8th 2015
Di Fan, Laura A Coughlin, Megan M Neubauer, Jiwoong Kim, Min Soo Kim, Xiaowei Zhan, Tiffany R Simms-Waldrip, Yang Xie, Lora V Hooper, Andrew Y Koh

18) Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR (Nature Medicine) Monday June 1st 2015
Miguel Vizoso, Humberto J Ferreira, Paula Lopez-Serra, F Javier Carmona, Anna Mart, Maria Romina Girotti, Alberto Villanueva, Sonia Guil, Catia Moutinho, Julia Liz, Anna Portela, Holger Heyn, Sebastian Moran, August Vidal, Maria Martinez-Iniesta, Jose L Manzano, Maria Teresa Fernandez-Figueras, Elena Elez, Eva Mu, Rafael Botella-Estrada, Alfonso Berrocal, Fredrik Pont, Joost van den Oord, William M Gallagher, Dennie T Frederick, Keith T Flaherty, Ultan McDermott, Paul Lorigan, Richard Marais, Manel Esteller

19) Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients (Nature Medicine) Monday June 1st 2015
Giulia Siravegna, Benedetta Mussolin, Michela Buscarino, Giorgio Corti, Andrea Cassingena, Giovanni Crisafulli, Agostino Ponzetti, Chiara Cremolini, Alessio Amatu, Calogero Lauricella, Simona Lamba, Sebastijan Hobor, Antonio Avallone, Emanuele Valtorta, Giuseppe Rospo, Enzo Medico, Valentina Motta, Carlotta Antoniotti, Fabiana Tatangelo, Beatriz Bellosillo, Silvio Veronese, Alfredo Budillon, Clara Montagut, Patrizia Racca, Silvia Marsoni, Alfredo Falcone, Ryan B Corcoran, Federica Di Nicolantonio, Fotios Loupakis, Salvatore Siena, Andrea Sartore-Bianchi, Alberto Bardelli

20) Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1- (Nature Medicine) Monday May 25th 2015
Ivan D Mascanfroni, Maisa C Takenaka, Ada Yeste, Bonny Patel, Yan Wu, Jessica E Kenison, Shafiuddin Siddiqui, Alexandre S Basso, Leo E Otterbein, Drew M Pardoll, Fan Pan, Avner Priel, Clary B Clish, Simon C Robson, Francisco J Quintana

21) The Cyclophilin A (Nature Medicine) Monday May 25th 2015
Di Zhu, Zhongqiu Wang, Jian-Jun Zhao, Teresa Calimeri, Jiang Meng, Teru Hideshima, Mariateresa Fulciniti, Yue Kang, Scott B Ficarro, Yu-Tzu Tai, Zachary Hunter, Douglas McMilin, Haoxuan Tong, Constantine S Mitsiades, Catherine J Wu, Steven P Treon, David M Dorfman, Geraldine Pinkus, Nikhil C Munshi, Pierfrancesco Tassone, Jarrod A Marto, Kenneth C Anderson, Ruben D Carrasco

22) The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes (Nature Medicine) Monday May 18th 2015
Bengt-Frederik Belgardt, Kashan Ahmed, Martina Spranger, Mathieu Latreille, Remy Denzler, Nadiia Kondratiuk, Ferdinand von Meyenn, Felipe Nunez Villena, Karolin Herrmanns, Domenico Bosco, Julie Kerr-Conte, Francois Pattou, Thomas R, Markus Stoffel

23) KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis (Nature Medicine) Monday May 18th 2015
Laura S Shankman, Delphine Gomez, Olga A Cherepanova, Morgan Salmon, Gabriel F Alencar, Ryan M Haskins, Pamela Swiatlowska, Alexandra A C Newman, Elizabeth S Greene, Adam C Straub, Brant Isakson, Gwendalyn J Randolph, Gary K Owens

24) Negative feedback (Nature Medicine) Monday May 11th 2015
Benshang Li, Hui Li, Yun Bai, Renate Kirschner-Schwabe, Jun J Yang, Yao Chen, Gang Lu, Gannie Tzoneva, Xiaotu Ma, Tongmin Wu, Wenjing Li, Haisong Lu, Lixia Ding, Huanhuan Liang, Xiaohang Huang, Minjun Yang, Lei Jin, Hui Kang, Shuting Chen, Alicia Du, Shuhong Shen, Jianping Ding, Hongzhuan Chen, Jing Chen, Arend von Stackelberg, Longjun Gu, Jinghui Zhang, Adolfo Ferrando, Jingyan Tang, Shengyue Wang, Bin-Bing S Zhou

25) Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells (Nature Medicine) Monday May 11th 2015
Laura J Pallett, Upkar S Gill, Alberto Quaglia, Linda V Sinclair, Maria Jover-Cobos, Anna Schurich, Kasha P Singh, Niclas Thomas, Abhishek Das, Antony Chen, Giuseppe Fusai, Antonio Bertoletti, Doreen A Cantrell, Patrick T Kennedy, Nathan A Davies, Muzlifah Haniffa, Mala K Maini

26) Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models (Nature Medicine) Monday May 11th 2015
Mario Schiffer, Beina Teng, Changkyu Gu, Valentina A Shchedrina, Marina Kasaikina, Vincent A Pham, Nils Hanke, Song Rong, Faikah Gueler, Patricia Schroder, Irini Tossidou, Joon-Keun Park, Lynne Staggs, Hermann Haller, Sergej Erschow, Denise Hilfiker-Kleiner, Changli Wei, Chuang Chen, Nicholas Tardi, Samy Hakroush, Martin K Selig, Aleksandr Vasilyev, Sandra Merscher, Jochen Reiser, Sanja Sever

27) Common clonal origin of central and resident memory T cells following skin immunization (Nature Medicine) Monday May 11th 2015
Olivier Gaide, Ryan O Emerson, Xiaodong Jiang, Nicholas Gulati, Suzanne Nizza, Cindy Desmarais, Harlan Robins, James G Krueger, Rachael A Clark, Thomas S Kupper

28) Functionally defined therapeutic targets in diffuse intrinsic pontine glioma (Nature Medicine) Monday May 4th 2015
Catherine S Grasso, Yujie Tang, Nathalene Truffaux, Noah E Berlow, Lining Liu, Marie-Anne Debily, Michael J Quist, Lara E Davis, Elaine C Huang, Pamelyn J Woo, Anitha Ponnuswami, Spenser Chen, Tessa B Johung, Wenchao Sun, Mari Kogiso, Yuchen Du, Lin Qi, Yulun Huang, Marianne H, Katherine E Warren, Ludivine Le Dret, Paul S Meltzer, Hua Mao, Martha Quezado, Dannis G van Vuurden, Jinu Abraham, Maryam Fouladi, Matthew N Svalina, Nicholas Wang, Cynthia Hawkins, Javad Nazarian, Marta M Alonso, Eric H Raabe, Esther Hulleman, Paul T Spellman, Xiao-Nan Li, Charles Keller, Ranadip Pal, Jacques Grill, Michelle Monje

29) Acquired EGFR C797S mutation mediates resistance to AZD9291 in non (Nature Medicine) Monday May 4th 2015
Kenneth S Thress, Cloud P Paweletz, Enriqueta Felip, Byoung Chul Cho, Daniel Stetson, Brian Dougherty, Zhongwu Lai, Aleksandra Markovets, Ana Vivancos, Yanan Kuang, Dalia Ercan, Sarah E Matthews, Mireille Cantarini, J Carl Barrett, Pasi A J, Geoffrey R Oxnard

30) Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity (Nature Medicine) Monday May 4th 2015
Elise Dalmas, Amine Toubal, Fawaz Alzaid, Katrina Blazek, Hayley L Eames, Kristell Lebozec, Maria Pini, Isabelle Hainault, Emilie Montastier, Rapha, Patricia Ancel, Am, Yin Ling, Omran Allatif, C, S, Nathalie Viguerie, Christine Poitou, Vladimir Stich, Alexandra Torcivia, Fabienne Foufelle, Serge Luquet, Judith Aron-Wisnewsky, Dominique Langin, Karine Cl, Irina A Udalova, Nicolas Venteclef

31) 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors (Nature Medicine) Monday May 4th 2015
Adrienne H Long, Waleed M Haso, Jack F Shern, Kelsey M Wanhainen, Meera Murgai, Maria Ingaramo, Jillian P Smith, Alec J Walker, M Eric Kohler, Vikas R Venkateshwara, Rosandra N Kaplan, George H Patterson, Terry J Fry, Rimas J Orentas, Crystal L Mackall

32) Photovoltaic restoration of sight with high visual acuity (Nature Medicine) Monday April 27th 2015
Henri Lorach, Georges Goetz, Richard Smith, Xin Lei, Yossi Mandel, Theodore Kamins, Keith Mathieson, Philip Huie, James Harris, Alexander Sher, Daniel Palanker

33) The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell (Nature Medicine) Monday April 27th 2015
Lucas Vicu, David E Strochlic, Alban Latremoliere, Kiran Kumar Bali, Manuela Simonetti, Dewi Husainie, Sandra Prokosch, Priscilla Riva, Robert S Griffin, Christian Njoo, Stefanie Gehrig, Marcus A Mall, Bernd Arnold, Marshall Devor, Clifford J Woolf, Stephen D Liberles, Michael Costigan, Rohini Kuner

34) Homeostatic regulation of T cell trafficking by a B cell (Nature Medicine) Monday April 20th 2015
Myriam Chimen, Helen M McGettrick, Bonita Apta, Sahithi J Kuravi, Clara M Yates, Amy Kennedy, Arjun Odedra, Mohammed Alassiri, Matthew Harrison, Ashley Martin, Francesca Barone, Saba Nayar, Jessica R Hitchcock, Adam F Cunningham, Karim Raza, Andrew Filer, David A Copland, Andrew D Dick, Joseph Robinson, Neena Kalia, Lucy S K Walker, Christopher D Buckley, Gerard B Nash, Parth Narendran, G Ed Rainger

35) Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes (Nature Medicine) Monday April 20th 2015
Razvan Cristescu, Jeeyun Lee, Michael Nebozhyn, Kyoung-Mee Kim, Jason C Ting, Swee Seong Wong, Jiangang Liu, Yong Gang Yue, Jian Wang, Kun Yu, Xiang S Ye, In-Gu Do, Shawn Liu, Lara Gong, Jake Fu, Jason Gang Jin, Min Gew Choi, Tae Sung Sohn, Joon Ho Lee, Jae Moon Bae, Seung Tae Kim, Se Hoon Park, Insuk Sohn, Sin-Ho Jung, Patrick Tan, Ronghua Chen, James Hardwick, Won Ki Kang, Mark Ayers, Dai Hongyue, Christoph Reinhard, Andrey Loboda, Sung Kim, Amit Aggarwal

36) Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization (Nature Medicine) Monday April 20th 2015
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, R, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Ch

37) Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion (Nature Medicine) Monday April 20th 2015
Caroline Bonner, Julie Kerr-Conte, Val, Gurvan Queniat, Ericka Moerman, Julien Th, C, Nathalie Delalleau, Iuliana Popescu, Willy J Malaisse, Abdullah Sener, Benoit Deprez, Amar Abderrahmani, Bart Staels, Fran

38) Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity (Nature Medicine) Monday April 20th 2015
Carolina S Ilkow, Monique Marguerie, Cory Batenchuk, Justin Mayer, Daniela Ben Neriah, Sophie Cousineau, Theresa Falls, Victoria A Jennings, Meaghan Boileau, David Bellamy, Donald Bastin, Christiano Tanese de Souza, Almohanad Alkayyal, Jiqing Zhang, Fabrice Le Boeuf, Rozanne Arulanandam, Lawton Stubbert, Padma Sampath, Steve H Thorne, Piriya Paramanthan, Avijit Chatterjee, Robert M Strieter, Marie Burdick, Christina L Addison, David F Stojdl, Harold L Atkins, Rebecca C Auer, Jean-Simon Diallo, Brian D Lichty, John C Bell

39) Studying clonal dynamics in response to cancer therapy using high-complexity barcoding (Nature Medicine) Monday April 13th 2015
Hyo-eun C Bhang, David A Ruddy, Viveksagar Krishnamurthy Radhakrishna, Justina X Caushi, Rui Zhao, Matthew M Hims, Angad P Singh, Iris Kao, Daniel Rakiec, Pamela Shaw, Marissa Balak, Alina Raza, Elizabeth Ackley, Nicholas Keen, Michael R Schlabach, Michael Palmer, Rebecca J Leary, Derek Y Chiang, William R Sellers, Franziska Michor, Vesselina G Cooke, Joshua M Korn, Frank Stegmeier

40) Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer (Nature Medicine) Monday April 13th 2015
Shuo Wei, Shingo Kozono, Lev Kats, Morris Nechama, Wenzong Li, Jlenia Guarnerio, Manli Luo, Mi-Hyeon You, Yandan Yao, Asami Kondo, Hai Hu, Gunes Bozkurt, Nathan J Moerke, Shugeng Cao, Markus Reschke, Chun-Hau Chen, Eduardo M Rego, Francesco Lo-Coco, Lewis C Cantley, Tae Ho Lee, Hao Wu, Yan Zhang, Pier Paolo Pandolfi, Xiao Zhen Zhou, Kun Ping Lu

41) Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes (Nature Medicine) Monday April 13th 2015
Ignazio Caruana, Barbara Savoldo, Valentina Hoyos, Gerrit Weber, Hao Liu, Eugene S Kim, Michael M Ittmann, Dario Marchetti, Gianpietro Dotti

42) Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network (Nature Medicine) Monday April 6th 2015
Cl, Brittany A Rasmussen, Frank A Duca, Melika Zadeh-Tahmasebi, Joseph A Baur, Mira Daljeet, Danna M Breen, Beatrice M Filippi, Tony K T Lam

43) Metformin activates a duodenal Ampk (Nature Medicine) Monday April 6th 2015
Frank A Duca, Cl, Brittany A Rasmussen, Melika Zadeh-Tahmasebi, Guy A Rutter, Beatrice M Filippi, Tony K T Lam

44) An unknown enemy: Drugs sought against EV-68 as paralysis link is explored (Nature Medicine) Monday March 30th 2015
Cassandra Willyard

45) DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia (Nature Medicine) Monday March 30th 2015
Chun-Wei Chen, Richard P Koche, Amit U Sinha, Aniruddha J Deshpande, Nan Zhu, Rowena Eng, John G Doench, Haiming Xu, Scott H Chu, Jun Qi, Xi Wang, Christopher Delaney, Kathrin M Bernt, David E Root, William C Hahn, James E Bradner, Scott A Armstrong

46) Targeting the MLL complex in castration-resistant prostate cancer (Nature Medicine) Monday March 30th 2015
Rohit Malik, Amjad P Khan, Irfan A Asangani, Marcin Cie, John R Prensner, Xiaoju Wang, Matthew K Iyer, Xia Jiang, Dmitry Borkin, June Escara-Wilke, Rachell Stender, Yi-Mi Wu, Yashar S Niknafs, Xiaojun Jing, Yuanyuan Qiao, Nallasivam Palanisamy, Lakshmi P Kunju, Pranathi M Krishnamurthy, Anastasia K Yocum, Dattatreya Mellacheruvu, Alexey I Nesvizhskii, Xuhong Cao, Saravana M Dhanasekaran, Felix Y Feng, Jolanta Grembecka, Tomasz Cierpicki, Arul M Chinnaiyan

47) Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection (Nature Medicine) Monday March 23rd 2015
Jonathan H Chen, Curtis J Perry, Yao-Chen Tsui, Matthew M Staron, Ian A Parish, Claudia X Dominguez, Daniel W Rosenberg, Susan M Kaech

48) Activation of AMPK (Nature Medicine) Monday March 23rd 2015
Yue Wu, Ping Song, Wencheng Zhang, Junhui Liu, Xiaoyan Dai, Zhaoyu Liu, Qiulun Lu, Changhan Ouyang, Zhonglin Xie, Zhengxing Zhao, Xiaozhen Zhuo, Benoit Viollet, Marc Foretz, Jiliang Wu, Zuyi Yuan, Ming-Hui Zou

49) Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy (Nature Medicine) Monday March 23rd 2015
Jae Seok Lim, Woo-il Kim, Hoon-Chul Kang, Se Hoon Kim, Ah Hyung Park, Eun Kyung Park, Young-Wook Cho, Sangwoo Kim, Ho Min Kim, Jeong A Kim, Junho Kim, Hwanseok Rhee, Seok-Gu Kang, Heung Dong Kim, Daesoo Kim, Dong-Seok Kim, Jeong Ho Lee

50) Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome (Nature Medicine) Monday March 16th 2015
Gabriele Deidda, Martina Parrini, Shovan Naskar, Ignacio F Bozarth, Andrea Contestabile, Laura Cancedda

51) Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment (Nature Medicine) Monday March 16th 2015
Jan Marquard, Silke Otter, Alena Welters, Alin Stirban, Annelie Fischer, Jan Eglinger, Diran Herebian, Olaf Kletke, Ma, Andra, Stephan Wnendt, Lorenzo Piemonti, Martin K, Jorge Ferrer, Bernard Thorens, Freimut Schliess, Marjan Slak Rupnik, Tim Heise, Per-Olof Berggren, Nikolaj Kl, Thomas Meissner, Ertan Mayatepek, Daniel Eberhard, Martin Kragl, Eckhard Lammert

52) Genetic and functional characterization of clonally derived adult human brown adipocytes (Nature Medicine) Monday March 16th 2015
Kosaku Shinoda, Ineke H N Luijten, Yutaka Hasegawa, Haemin Hong, Si B Sonne, Miae Kim, Ruidan Xue, Maria Chondronikola, Aaron M Cypess, Yu-Hua Tseng, Jan Nedergaard, Labros S Sidossis, Shingo Kajimura

53) RIFINs are adhesins implicated in severe Plasmodium falciparum malaria (Nature Medicine) Monday March 9th 2015
Suchi Goel, Mia Palmkvist, Kirsten Moll, Nicolas Joannin, Patricia Lara, Reetesh R Akhouri, Nasim Moradi, Karin, Mattias Westman, Davide Angeletti, Hanna Kjellin, Janne Lehti, Ola Blixt, Lars Idestr, Carl G Gahmberg, Jill R Storry, Annika K Hult, Martin L Olsson, Gunnar von Heijne, IngMarie Nilsson, Mats Wahlgren

54) Myocardial healing requires Reg3 (Nature Medicine) Monday March 9th 2015
Holger L, Jochen P, Praveen Gajawada, Yunlong Hou, Viktoria Polyakova, Sawa Kostin, Juan M Adrian-Segarra, Thomas Boettger, Astrid Wietelmann, Henning Warnecke, Manfred Richter, Thomas Kubin, Thomas Braun

55) A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication (Nature Medicine) Monday March 9th 2015
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Oca, Andrew F Stewart

56) A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis (Nature Medicine) Monday March 2nd 2015
Bappaditya Dey, Ruchi Jain Dey, Laurene S Cheung, Supriya Pokkali, Haidan Guo, Jong-Hee Lee, William R Bishai

57) Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps (Nature Medicine) Monday March 2nd 2015
Tiannan Guo, Petri Kouvonen, Ching Chiek Koh, Ludovic C Gillet, Witold E Wolski, Hannes L R, George Rosenberger, Ben C Collins, Lorenz C Blum, Silke Gillessen, Markus Joerger, Wolfram Jochum, Ruedi Aebersold

58) LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes (Nature Medicine) Monday February 23rd 2015
Pingping Li, Da Young Oh, Gautam Bandyopadhyay, William S Lagakos, Saswata Talukdar, Olivia Osborn, Andrew Johnson, Heekyung Chung, Rafael Mayoral, Michael Maris, Jachelle M Ofrecio, Sayaka Taguchi, Min Lu, Jerrold M Olefsky

59) Modeling colorectal cancer using CRISPR-Cas9 (Nature Medicine) Monday February 23rd 2015
Mami Matano, Shoichi Date, Mariko Shimokawa, Ai Takano, Masayuki Fujii, Yuki Ohta, Toshiaki Watanabe, Takanori Kanai, Toshiro Sato

60) DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine (Nature Medicine) Monday February 23rd 2015
Keizo Nishikawa, Yoriko Iwamoto, Yasuhiro Kobayashi, Fumiki Katsuoka, Shin-ichi Kawaguchi, Tadayuki Tsujita, Takashi Nakamura, Shigeaki Kato, Masayuki Yamamoto, Hiroshi Takayanagi, Masaru Ishii

61) Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers (Nature Medicine) Monday February 16th 2015
Benjamin G Bitler, Katherine M Aird, Azat Garipov, Hua Li, Michael Amatangelo, Andrew V Kossenkov, David C Schultz, Qin Liu, Ie-Ming Shih, Jose R Conejo-Garcia, David W Speicher, Rugang Zhang

62) A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease (Nature Medicine) Monday February 9th 2015
Mathias Riebold, Christian Kozany, Lee Freiburger, Michael Sattler, Michael Buchfelder, Felix Hausch, G, Marcelo Paez-Pereda

63) Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference (Nature Medicine) Monday February 9th 2015
Chao Liang, Baosheng Guo, Heng Wu, Ningsheng Shao, Defang Li, Jin Liu, Lei Dang, Cheng Wang, Hui Li, Shaohua Li, Wing Ki Lau, Yu Cao, Zhijun Yang, Cheng Lu, Xiaojuan He, D W T Au, Xiaohua Pan, Bao-Ting Zhang, Changwei Lu, Hongqi Zhang, Kinman Yue, Airong Qian, Peng Shang, Jiake Xu, Lianbo Xiao, Zhaoxiang Bian, Weihong Tan, Zicai Liang, Fuchu He, Lingqiang Zhang, Aiping Lu, Ge Zhang

64) Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers (Nature Medicine) Monday February 2nd 2015
Aur, Graziella Griffith, Arran Babbs, Samir El Andaloussi, Kariem Ezzat, Aur, Branislav Dugovic, R, Arnaud Ferry, Thomas Voit, Helge Amthor, Claudia B, Stefan Sch, Matthew J A Wood, Kay E Davies, Cyrille Vaillend, Christian Leumann, Luis Garcia

65) Access sought to tuberculosis drug from nutraceutical company (Nature Medicine) Monday February 2nd 2015
Karl Gruber

66) B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers (Nature Medicine) Monday January 19th 2015
Yoshinori Fukazawa, Richard Lum, Afam A Okoye, Haesun Park, Kenta Matsuda, Jin Young Bae, Shoko I Hagen, Rebecca Shoemaker, Claire Deleage, Carissa Lucero, David Morcock, Tonya Swanson, Alfred W Legasse, Michael K Axthelm, Joseph Hesselgesser, Romas Geleziunas, Vanessa M Hirsch, Paul T Edlefsen, Michael Piatak, Jacob D Estes, Jeffrey D Lifson, Louis J Picker

67) Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia (Nature Medicine) Monday January 19th 2015
Steven M Chan, Daniel Thomas, M Ryan Corces-Zimmerman, Seethu Xavy, Suchita Rastogi, Wan-Jen Hong, Feifei Zhao, Bruno C Medeiros, David A Tyvoll, Ravindra Majeti

68) Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction (Nature Medicine) Monday January 12th 2015
Mortimer Korf-Klingebiel, Marc R Reboll, Stefanie Klede, Torben Brod, Andreas Pich, Felix Polten, L Christian Napp, Johann Bauersachs, Arnold Ganser, Eva Brinkmann, Ines Reimann, Tibor Kempf, Hans W Niessen, Jacques Mizrahi, Hans-Joachim Sch, Antonio Iglesias, Maria Bobadilla, Yong Wang, Kai C Wollert

69) Orphan nuclear receptor NR4A1 regulates transforming growth factor- (Nature Medicine) Monday January 12th 2015
Katrin Palumbo-Zerr, Pawel Zerr, Alfiya Distler, Judith Fliehr, Rossella Mancuso, Jingang Huang, Dirk Mielenz, Michal Tomcik, Barbara G F, Carina Scholtysek, Clara Dees, Christian Beyer, Gerhard Kr, Daniel Metzger, Oliver Distler, Georg Schett, J

70) Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes (Nature Medicine) Monday January 12th 2015
Cong Tang, Kashan Ahmed, Andreas Gille, Shun Lu, Hermann-Josef Gr, Sorin Tunaru, Stefan Offermanns

71) Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance (Nature Medicine) Monday January 5th 2015
Sungsoon Fang, Jae Myoung Suh, Shannon M Reilly, Elizabeth Yu, Olivia Osborn, Denise Lackey, Eiji Yoshihara, Alessia Perino, Sandra Jacinto, Yelizaveta Lukasheva, Annette R Atkins, Alexander Khvat, Bernd Schnabl, Ruth T Yu, David A Brenner, Sally Coulter, Christopher Liddle, Kristina Schoonjans, Jerrold M Olefsky, Alan R Saltiel, Michael Downes, Ronald M Evans

72) Structure-inherent targeting of near-infrared fluorophores for parathyroid and thyroid gland imaging (Nature Medicine) Monday January 5th 2015
Hoon Hyun, Min Ho Park, Eric A Owens, Hideyuki Wada, Maged Henary, Henricus J M Handgraaf, Alexander L Vahrmeijer, John V Frangioni, Hak Soo Choi

73) High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma (Nature Medicine) Monday December 22nd 2014
Carsten Linnemann, Marit M van Buuren, Laura Bies, Els M E Verdegaal, Remko Schotte, Jorg J A Calis, Sam Behjati, Arno Velds, Henk Hilkmann, Dris el Atmioui, Marten Visser, Michael R Stratton, John B A G Haanen, Hergen Spits, Sjoerd H van der Burg, Ton N M Schumacher

74) Notch controls the survival of memory CD4+ T cells by regulating glucose uptake (Nature Medicine) Monday December 15th 2014
Yoichi Maekawa, Chieko Ishifune, Shin-ichi Tsukumo, Katsuto Hozumi, Hideo Yagita, Koji Yasutomo

75) Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia (Nature Medicine) Monday December 15th 2014
Christopher S Fry, Jonah D Lee, Jyothi Mula, Tyler J Kirby, Janna R Jackson, Fujun Liu, Lin Yang, Christopher L Mendias, Esther E Dupont-Versteegden, John J McCarthy, Charlotte A Peterson

76) In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire (Nature Medicine) Monday December 15th 2014
Brandon J DeKosky, Takaaki Kojima, Alexa Rodin, Wissam Charab, Gregory C Ippolito, Andrew D Ellington, George Georgiou

77) Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles (Nature Medicine) Monday December 15th 2014
Sarah A Stanley, Jeremy Sauer, Ravi S Kane, Jonathan S Dordick, Jeffrey M Friedman

78) A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents (Nature Medicine) Monday December 8th 2014
Brian Finan, Bin Yang, Nickki Ottaway, David L Smiley, Tao Ma, Christoffer Clemmensen, Joe Chabenne, Lianshan Zhang, Kirk M Habegger, Katrin Fischer, Jonathan E Campbell, Darleen Sandoval, Randy J Seeley, Konrad Bleicher, Sabine Uhles, William Riboulet, J, Cornelia Hertel, Sara Belli, Elena Sebokova, Karin Conde-Knape, Anish Konkar, Daniel J Drucker, Vasily Gelfanov, Paul T Pfluger, Timo D M, Diego Perez-Tilve, Richard D DiMarchi, Matthias H Tsch

79) The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling (Nature Medicine) Monday December 8th 2014
Renata Grozovsky, Antonija Jurak Begonja, Kaifeng Liu, Gary Visner, John H Hartwig, Herv, Karin M Hoffmeister

80) Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy (Nature Medicine) Monday December 8th 2014
Norihiko Yokoi, Yuko Fukata, Daisuke Kase, Taisuke Miyazaki, Martine Jaegle, Toshika Ohkawa, Naoki Takahashi, Hiroko Iwanari, Yasuhiro Mochizuki, Takao Hamakubo, Keiji Imoto, Dies Meijer, Masahiko Watanabe, Masaki Fukata

81) Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis (Nature Medicine) Monday December 8th 2014
Justin D Crane, Rengasamy Palanivel, Emilio P Mottillo, Adam L Bujak, Huaqing Wang, Rebecca J Ford, Andrew Collins, Regje M Bl, Morgan D Fullerton, Julian M Yabut, Janice J Kim, Jean-Eric Ghia, Shereen M Hamza, Katherine M Morrison, Jonathan D Schertzer, Jason R B Dyck, Waliul I Khan, Gregory R Steinberg

82) Mutations in G protein (Nature Medicine) Monday December 8th 2014
Akinori Yoda, Guillaume Adelmant, Jerome Tamburini, Bjoern Chapuy, Nobuaki Shindoh, Yuka Yoda, Oliver Weigert, Nadja Kopp, Shuo-Chieh Wu, Sunhee S Kim, Huiyun Liu, Trevor Tivey, Amanda L Christie, Kutlu G Elpek, Joseph Card, Kira Gritsman, Jason Gotlib, Michael W Deininger, Hideki Makishima, Shannon J Turley, Nathalie Javidi-Sharifi, Jaroslaw P Maciejewski, Siddhartha Jaiswal, Benjamin L Ebert, Scott J Rodig, Jeffrey W Tyner, Jarrod A Marto, David M Weinstock, Andrew A Lane

83) Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche (Nature Medicine) Monday December 1st 2014
Hayley Davis, Shazia Irshad, Mukesh Bansal, Hannah Rafferty, Tatjana Boitsova, Chiara Bardella, Emma Jaeger, Annabelle Lewis, Luke Freeman-Mills, Francesc C Giner, Pedro Rodenas-Cuadrado, Sreelakshmi Mallappa, Susan Clark, Huw Thomas, Rosemary Jeffery, Richard Poulsom, Manuel Rodriguez-Justo, Marco Novelli, Runjan Chetty, Andrew Silver, Owen J Sansom, Florian R Greten, Lai Mun Wang, James E East, Ian Tomlinson, Simon J Leedham

84) Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development (Nature Medicine) Monday December 1st 2014
Hyun Mi Kang, Seon Ho Ahn, Peter Choi, Yi-An Ko, Seung Hyeok Han, Frank Chinga, Ae Seo Deok Park, Jianling Tao, Kumar Sharma, James Pullman, Erwin P Bottinger, Ira J Goldberg, Katalin Susztak

85) Targeting (Nature Medicine) Monday November 24th 2014
Siddappa N Byrareddy, Brianne Kallam, James Arthos, Claudia Cicala, Fatima Nawaz, Joseph Hiatt, Ellen N Kersh, Janet M McNicholl, Debra Hanson, Keith A Reimann, Markus Brameier, Lutz Walter, Kenneth Rogers, Ann E Mayne, Paul Dunbar, Tara Villinger, Dawn Little, Tristram G Parslow, Philip J Santangelo, Francois Villinger, Anthony S Fauci, Aftab A Ansari

86) Chronic enrichment of hepatic endoplasmic reticulum (Nature Medicine) Monday November 24th 2014
Ana Paula Arruda, Benedicte M Pers, G, Ekin G, Karen Inouye, G

87) Disruption of the PRKCD (Nature Medicine) Monday November 24th 2014
Ursula Baumann, Vanesa Fern, Martina Rudelius, Simone Lemeer, Roland Rad, Anna-Maria Knorn, Jolanta Slawska, Katharina Engel, Irmela Jeremias, Zhoulei Li, Viktoriya Tomiatti, Anna-Lena Illert, Bianca-Sabrina Targosz, Martin Braun, Sven Perner, Michael Leitges, Wolfram Klapper, Martin Dreyling, Cornelius Miething, Georg Lenz, Andreas Rosenwald, Christian Peschel, Ulrich Keller, Bernhard Kuster, Florian Bassermann

88) A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death (Nature Medicine) Monday November 24th 2014
Monica K Wetzel-Smith, Julie Hunkapiller, Tushar R Bhangale, Karpagam Srinivasan, Janice A Maloney, Jasvinder K Atwal, Susan M Sa, Murat B Yaylaoglu, Oded Foreman, Ward Ortmann, Nisha Rathore, David V Hansen, Marc Tessier-Lavigne, Richard Mayeux, Margaret Pericak-Vance, Jonathan Haines, Lindsay A Farrer, Gerard D Schellenberg, Alison Goate, Timothy W Behrens, Carlos Cruchaga, Ryan J Watts, Robert R Graham

89) Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma (Nature Medicine) Monday November 17th 2014
Rintaro Hashizume, Noemi Andor, Yuichiro Ihara, Robin Lerner, Haiyun Gan, Xiaoyue Chen, Dong Fang, Xi Huang, Maxwell W Tom, Vy Ngo, David Solomon, Sabine Mueller, Pamela L Paris, Zhiguo Zhang, Claudia Petritsch, Nalin Gupta, Todd A Waldman, C David James

90) Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia (Nature Medicine) Monday November 17th 2014
Eduardo Gascon, Kelleen Lynch, Hongyu Ruan, Sandra Almeida, Jamie M Verheyden, William W Seeley, Dennis W Dickson, Leonard Petrucelli, Danqiong Sun, Jian Jiao, Hongru Zhou, Mira Jakovcevski, Schahram Akbarian, Wei-Dong Yao, Fen-Biao Gao

91) The brown fat (Nature Medicine) Monday November 17th 2014
Guo-Xiao Wang, Xu-Yun Zhao, Zhuo-Xian Meng, Matthias Kern, Arne Dietrich, Zhimin Chen, Zoharit Cozacov, Dequan Zhou, Adewole L Okunade, Xiong Su, Siming Li, Matthias Bl, Jiandie D Lin

92) Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes (Nature Medicine) Monday November 10th 2014
Menna R Clatworthy, Caren E Petrie Aronin, Rebeccah J Mathews, Nicole Y Morgan, Kenneth G C Smith, Ronald N Germain

93) Longitudinal PET-MRI reveals (Nature Medicine) Monday November 10th 2014
Florian C Maier, Hans F Wehrl, Andreas M Schmid, Julia G Mannheim, Stefan Wiehr, Chommanad Lerdkrai, Carsten Calaminus, Anke Stahlschmidt, Lan Ye, Michael Burnet, Detlef Stiller, Osama Sabri, Gerald Reischl, Mathias Staufenbiel, Olga Garaschuk, Mathias Jucker, Bernd J Pichler

94) Anchored multiplex PCR for targeted next-generation sequencing (Nature Medicine) Monday November 10th 2014
Zongli Zheng, Matthew Liebers, Boryana Zhelyazkova, Yi Cao, Divya Panditi, Kerry D Lynch, Juxiang Chen, Hayley E Robinson, Hyo Sup Shim, Juliann Chmielecki, William Pao, Jeffrey A Engelman, A John Iafrate, Long Phi Le

95) University travel bans and quarantines may impede Ebola response (Nature Medicine) Monday November 10th 2014
Cassandra Willyard

96) Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress (Nature Medicine) Sunday November 2nd 2014
Sumaira Z Hasnain, Danielle J Borg, Brooke E Harcourt, Hui Tong, Yonghua H Sheng, Choa Ping Ng, Indrajit Das, Ran Wang, Alice C-H Chen, Thomas Loudovaris, Thomas W Kay, Helen E Thomas, Jonathan P Whitehead, Josephine M Forbes, Johannes B Prins, Michael A McGuckin

97) An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease (Nature Medicine) Sunday November 2nd 2014
Ryosuke Kikuchi, Kazuto Nakamura, Susan MacLauchlan, Doan Thi-Minh Ngo, Ippei Shimizu, Jose Javier Fuster, Yasufumi Katanasaka, Sumiko Yoshida, Yan Qiu, Terry P Yamaguchi, Tadashi Matsushita, Toyoaki Murohara, Noyan Gokce, David O Bates, Naomi M Hamburg, Kenneth Walsh

98) A role for interleukin-22 in the alleviation of metabolic syndrome (Nature Medicine) Sunday November 2nd 2014
Elise Dalmas, Marc Y Donath

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Mitch Andre Garcia's Chem Feeds 2008-present

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