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1) Reference genome sequence of the model plant Setaria (Nature Biotechnology) Sunday May 13th 2012
Jeffrey L Bennetzen, Jeremy Schmutz, Hao Wang, Ryan Percifield, Jennifer Hawkins, Ana C Pontaroli, Matt Estep, Liang Feng, Justin N Vaughn, Jane Grimwood, Jerry Jenkins, Kerrie Barry, Erika Lindquist, Uffe Hellsten, Shweta Deshpande, Xuewen Wang, Xiaomei Wu, Therese Mitros, Jimmy Triplett, Xiaohan Yang, Chu-Yu Ye, Margarita Mauro-Herrera, Lin Wang, Pinghua Li, Manoj Sharma, Rita Sharma, Pamela C Ronald, Olivier Panaud, Elizabeth A Kellogg, Thomas P Brutnell, Andrew N Doust, Gerald A Tuskan, Daniel Rokhsar, Katrien M Devos

2) Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential (Nature Biotechnology) Sunday May 13th 2012
Gengyun Zhang, Xin Liu, Zhiwu Quan, Shifeng Cheng, Xun Xu, Shengkai Pan, Min Xie, Peng Zeng, Zhen Yue, Wenliang Wang, Ye Tao, Chao Bian, Changlei Han, Qiuju Xia, Xiaohua Peng, Rui Cao, Xinhua Yang, Dongliang Zhan, Jingchu Hu, Yinxin Zhang, Henan Li, Hua Li, Ning Li, Junyi Wang, Chanchan Wang, Renyi Wang, Tao Guo, Yanjie Cai, Chengzhang Liu, Haitao Xiang, Qiuxiang Shi, Ping Huang, Qingchun Chen, Yingrui Li, Jun Wang, Zhihai Zhao, Jian Wang

3) Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting (Nature Biotechnology) Sunday April 29th 2012
Jun Fu, Xiaoying Bian, Shengbaio Hu, Hailong Wang, Fan Huang, Philipp M Seibert, Alberto Plaza, Liqiu Xia, Rolf Müller, A Francis Stewart, Youming Zhang

4) Absolute quantification of somatic DNA alterations in human cancer (Nature Biotechnology) Sunday April 29th 2012
Scott L Carter, Kristian Cibulskis, Elena Helman, Aaron McKenna, Hui Shen, Travis Zack, Peter W Laird, Robert C Onofrio, Wendy Winckler, Barbara A Weir, Rameen Beroukhim, David Pellman, Douglas A Levine, Eric S Lander, Matthew Meyerson, Gad Getz

5) Performance comparison of benchtop high-throughput sequencing platforms (Nature Biotechnology) Sunday April 22nd 2012
Nicholas J Loman, Raju V Misra, Timothy J Dallman, Chrystala Constantinidou, Saheer E Gharbia, John Wain, Mark J Pallen

6) FLASH assembly of TALENs for high-throughput genome editing (Nature Biotechnology) Sunday April 8th 2012
Deepak Reyon, Shengdar Q Tsai, Cyd Khayter, Jennifer A Foden, Jeffry D Sander, J Keith Joung

7) A proteomics approach for the identification and cloning of monoclonal antibodies from serum (Nature Biotechnology) Sunday March 25th 2012
Wan Cheung Cheung, Sean A Beausoleil, Xiaowu Zhang, Shuji Sato, Sandra M Schieferl, James S Wieler, Jason G Beaudet, Ravi K Ramenani, Lana Popova, Michael J Comb, John Rush, Roberto D Polakiewicz

8) Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation (Nature Biotechnology) Sunday March 25th 2012
Farzaneh Modarresi, Mohammad Ali Faghihi, Miguel A Lopez-Toledano, Roya Pedram Fatemi, Marco Magistri, Shaun P Brothers, Marcel P van der Brug, Claes Wahlestedt

9) Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase (Nature Biotechnology) Sunday March 25th 2012
Elizabeth A Manrao, Ian M Derrington, Andrew H Laszlo, Kyle W Langford, Matthew K Hopper, Nathaniel Gillgren, Mikhail Pavlenok, Michael Niederweis, Jens H Gundlach

10) Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids (Nature Biotechnology) Sunday March 25th 2012
Fuzhong Zhang, James M Carothers, Jay D Keasling

11) Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma (Nature Biotechnology) Sunday March 18th 2012
Jose Pulido, Timothy Kottke, Jill Thompson, Feorillo Galivo, Phonphimon Wongthida, Rosa Maria Diaz, Diana Rommelfanger, Elizabeth Ilett, Larry Pease, Hardev Pandha, Kevin Harrington, Peter Selby, Alan Melcher, Richard Vile

12) Wheat grain yield on saline soils is improved by an ancestral Na+ transporter gene (Nature Biotechnology) Wednesday March 7th 2012
Rana Munns, Richard A James, Bo Xu, Asmini Athman, Simon J Conn, Charlotte Jordans, Caitlin S Byrt, Ray A Hare, Stephen D Tyerman, Mark Tester, Darren Plett, Matthew Gilliham

13) Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3 (Nature Biotechnology) Monday February 27th 2012
Barak Blum, Sini[sbreve]ša Hrvatin, Christian Schuetz, Claire Bonal, Alireza Rezania, Douglas A Melton

14) Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay (Nature Biotechnology) Monday February 27th 2012
Alexandre Melnikov, Anand Murugan, Xiaolan Zhang, Tiberiu Tesileanu, Li Wang, Peter Rogov, Soheil Feizi, Andreas Gnirke, Curtis G Callan, Justin B Kinney, Manolis Kellis, Eric S Lander, Tarjei S Mikkelsen

15) Massively parallel functional dissection of mammalian enhancers in vivo (Nature Biotechnology) Monday February 27th 2012
Rupali P Patwardhan, Joseph B Hiatt, Daniela M Witten, Mee J Kim, Robin P Smith, Dalit May, Choli Lee, Jennifer M Andrie, Su-In Lee, Gregory M Cooper, Nadav Ahituv, Len A Pennacchio, Jay Shendure

16) Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors (Nature Biotechnology) Sunday February 19th 2012
Elisabet Wahlberg, Tobias Karlberg, Ekaterina Kouznetsova, Natalia Markova, Antonio Macchiarulo, Ann-Gerd Thorsell, Ewa Pol, Åsa Frostell, Torun Ekblad, Delal Öncü, Björn Kull, Graeme Michael Robertson, Roberto Pellicciari, Herwig Schüler, Johan Weigelt

17) Automated forward and reverse ratcheting of DNA in a nanopore at 5-Å precision (Nature Biotechnology) Tuesday February 14th 2012
Gerald M Cherf, Kate R Lieberman, Hytham Rashid, Christopher E Lam, Kevin Karplus, Mark Akeson

18) Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome (Nature Biotechnology) Sunday February 12th 2012
Zhiyu Peng, Yanbing Cheng, Bertrand Chin-Ming Tan, Lin Kang, Zhijian Tian, Yuankun Zhu, Wenwei Zhang, Yu Liang, Xueda Hu, Xuemei Tan, Jing Guo, Zirui Dong, Yan Liang, Li Bao, Jun Wang

19) Genome sequencing reveals agronomically important loci in rice using MutMap (Nature Biotechnology) Sunday January 22nd 2012
Akira Abe, Shunichi Kosugi, Kentaro Yoshida, Satoshi Natsume, Hiroki Takagi, Hiroyuki Kanzaki, Hideo Matsumura, Kakoto Yoshida, Chikako Mitsuoka, Muluneh Tamiru, Hideki Innan, Liliana Cano, Sophien Kamoun, Ryohei Terauchi

20) Increased Diels-Alderase activity through backbone remodeling guided by Foldit players (Nature Biotechnology) Sunday January 22nd 2012
Christopher B Eiben, Justin B Siegel, Jacob B Bale, Seth Cooper, Firas Khatib, Betty W Shen, Foldit Players, Barry L Stoddard, Zoran Popovic, David Baker

21) Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates (Nature Biotechnology) Sunday January 22nd 2012
Ben-Quan Shen, Keyang Xu, Luna Liu, Helga Raab, Sunil Bhakta, Margaret Kenrick, Kathryn L Parsons-Reponte, Janet Tien, Shang-Fan Yu, Elaine Mai, Dongwei Li, Jay Tibbitts, Jakub Baudys, Ola M Saad, Suzie J Scales, Paul J McDonald, Philip E Hass, Charles Eigenbrot, Trung Nguyen, Willy A Solis, Reina N Fuji, Kelly M Flagella, Darshana Patel, Susan D Spencer, Leslie A Khawli, Allen Ebens, Wai Lee Wong, Richard Vandlen, Surinder Kaur, Mark X Sliwkowski, Richard H Scheller, Paul Polakis, Jagath R Junutula

22) Generation of human vascular smooth muscle subtypes provides insight into embryological origin–dependent disease susceptibility (Nature Biotechnology) Sunday January 15th 2012
Christine Cheung, Andreia S Bernardo, Matthew W B Trotter, Roger A Pedersen, Sanjay Sinha

23) Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure (Nature Biotechnology) Sunday January 15th 2012
Suraj J Patel, Jack M Milwid, Kevin R King, Stefan Bohr, Arvin Iracheta-Velle, Matthew Li, Antonia Vitalo, Biju Parekkadan, Rohit Jindal, Martin L Yarmush

24) Three-dimensional reconstruction of protein networks provides insight into human genetic disease (Nature Biotechnology) Sunday January 15th 2012
Xiujuan Wang, Xiaomu Wei, Bram Thijssen, Jishnu Das, Steven M Lipkin, Haiyuan Yu

25) Genome architectures revealed by tethered chromosome conformation capture and population-based modeling (Nature Biotechnology) Sunday December 25th 2011
Reza Kalhor, Harianto Tjong, Nimanthi Jayathilaka, Frank Alber, Lin Chen

26) Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing (Nature Biotechnology) Sunday December 18th 2011
Joke Reumers, Peter De Rijk, Hui Zhao, Anthony Liekens, Dominiek Smeets, John Cleary, Peter Van Loo, Maarten Van Den Bossche, Kirsten Catthoor, Bernard Sabbe, Evelyn Despierre, Ignace Vergote, Brian Hilbush, Diether Lambrechts, Jurgen Del-Favero

27) Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes (Nature Biotechnology) Sunday December 11th 2011
Xun Xu, Xin Liu, Song Ge, Jeffrey D Jensen, Fengyi Hu, Xin Li, Yang Dong, Ryan N Gutenkunst, Lin Fang, Lei Huang, Jingxiang Li, Weiming He, Guojie Zhang, Xiaoming Zheng, Fumin Zhang, Yingrui Li, Chang Yu, Karsten Kristiansen, Xiuqing Zhang, Jian Wang, Mark Wright, Susan McCouch, Rasmus Nielsen, Jun Wang, Wen Wang

28) Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (Nature Biotechnology) Sunday November 27th 2011
Kitai Kim, Rui Zhao, Akiko Doi, Kitwa Ng, Juli Unternaehrer, Patrick Cahan, Huo Hongguang, Yuin-Han Loh, Martin J Aryee, M William Lensch, Hu Li, James J Collins, Andrew P Feinberg, George Q Daley

29) Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage (Nature Biotechnology) Sunday November 27th 2011
Katherine Amps, Peter W Andrews, George Anyfantis, Lyle Armstrong, Stuart Avery, Hossein Baharvand, Julie Baker, Duncan Baker, Maria B Munoz, Stephen Beil, Nissim Benvenisty, Dalit Ben-Yosef, Juan-Carlos Biancotti, Alexis Bosman, Romulo Martin Brena, Daniel Brison, Gunilla Caisander, María V Camarasa, Jieming Chen, Eric Chiao, Young Min Choi, Andre B H Choo, Daniel Collins, Alan Colman, Jeremy M Crook, George Q Daley, Anne Dalton, Paul A De Sousa, Chris Denning, Janet Downie, Petr Dvorak, Karen D Montgomery, Anis Feki, Angela Ford, Victoria Fox, Ana M Fraga, Tzvia Frumkin, Lin Ge, Paul J Gokhale, Tamar Golan-Lev, Hamid Gourabi, Michal Gropp, Lu Guangxiu, Ales Hampl, Katie Harron, Lyn Healy, Wishva Herath, Frida Holm, Outi Hovatta, Johan Hyllner, Maneesha S Inamdar, Astrid Kresentia Irwanto, Tetsuya Ishii, Marisa Jaconi, Ying Jin, Susan Kimber, Sergey Kiselev, Barbara B Knowles, Oded Kopper, Valeri Kukharenko, Anver Kuliev, Maria A Lagarkova, Peter W Laird, Majlinda Lako, Andrew L Laslett, Neta Lavon, Dong Ryul Lee, Jeoung Eun Lee, Chunliang Li, Linda S Lim, Tenneille E Ludwig, Yu Ma, Edna Maltby, Ileana Mateizel, Yoav Mayshar, Maria Mileikovsky, Stephen L Minger, Takamichi Miyazaki, Shin Yong Moon, Harry Moore, Christine Mummery, Andras Nagy, Norio Nakatsuji, Kavita Narwani, Steve K W Oh, Sun Kyung Oh, Cia Olson, Timo Otonkoski, Fei Pan, In-Hyun Park, Steve Pells, Martin F Pera, Lygia V Pereira, Ouyang Qi, Grace Selva Raj, Benjamin Reubinoff, Alan Robins, Paul Robson, Janet Rossant, Ghasem H Salekdeh, Thomas C Schulz, Karen Sermon, Jameelah Sheik Mohamed, Hui Shen, Eric Sherrer, Kuldip Sidhu, Shirani Sivarajah, Heli Skottman, Claudia Spits, Glyn N Stacey, Raimund Strehl, Nick Strelchenko, Hirofumi Suemori, Bowen Sun, Riitta Suuronen, Kazutoshi Takahashi, Timo Tuuri, Parvathy Venu, Yuri Verlinsky, Dorien Ward-van Oostwaard, Daniel J Weisenberger, Yue Wu, Shinya Yamanaka, Lorraine Young, Qi Zhou

30) DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes (Nature Biotechnology) Sunday November 20th 2011
Subhajyoti De, Franziska Michor

31) High order chromatin architecture shapes the landscape of chromosomal alterations in cancer (Nature Biotechnology) Sunday November 20th 2011
Geoff Fudenberg, Gad Getz, Matthew Meyerson, Leonid A Mirny

32) Single-cell dissection of transcriptional heterogeneity in human colon tumors (Nature Biotechnology) Sunday November 13th 2011
Piero Dalerba, Tomer Kalisky, Debashis Sahoo, Pradeep S Rajendran, Michael E Rothenberg, Anne A Leyrat, Sopheak Sim, Jennifer Okamoto, Darius M Johnston, Dalong Qian, Maider Zabala, Janet Bueno, Norma F Neff, Jianbin Wang, Andrew A Shelton, Brendan Visser, Shigeo Hisamori, Yohei Shimono, Marc van de Wetering, Hans Clevers, Michael F Clarke, Stephen R Quake

33) Targeted RNA sequencing reveals the deep complexity of the human transcriptome (Nature Biotechnology) Sunday November 13th 2011
Tim R Mercer, Daniel J Gerhardt, Marcel E Dinger, Joanna Crawford, Cole Trapnell, Jeffrey A Jeddeloh, John S Mattick, John L Rinn

34) In silico feedback for in vivo regulation of a gene expression circuit (Nature Biotechnology) Sunday November 6th 2011
Andreas Milias-Argeitis, Sean Summers, Jacob Stewart-Ornstein, Ignacio Zuleta, David Pincus, Hana El-Samad, Mustafa Khammash, John Lygeros

35) Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop of resource-poor farmers (Nature Biotechnology) Sunday November 6th 2011
Rajeev K Varshney, Wenbin Chen, Yupeng Li, Arvind K Bharti, Rachit K Saxena, Jessica A Schlueter, Mark T A Donoghue, Sarwar Azam, Guangyi Fan, Adam M Whaley, Andrew D Farmer, Jaime Sheridan, Aiko Iwata, Reetu Tuteja, R Varma Penmetsa, Wei Wu, Hari D Upadhyaya, Shiaw-Pyng Yang, Trushar Shah, K B Saxena, Todd Michael, W Richard McCombie, Bicheng Yang, Gengyun Zhang, Huanming Yang, Jun Wang, Charles Spillane, Douglas R Cook, Gregory D May, Xun Xu, Scott A Jackson

36) Field performance of engineered male mosquitoes (Nature Biotechnology) Sunday October 30th 2011
Angela F Harris, Derric Nimmo, Andrew R McKemey, Nick Kelly, Sarah Scaife, Christl A Donnelly, Camilla Beech, William D Petrie, Luke Alphey

37) Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity (Nature Biotechnology) Sunday October 30th 2011
Theonie Anastassiadis, Sean W Deacon, Karthik Devarajan, Haiching Ma, Jeffrey R Peterson

38) Comprehensive analysis of kinase inhibitor selectivity (Nature Biotechnology) Sunday October 30th 2011
Mindy I Davis, Jeremy P Hunt, Sanna Herrgard, Pietro Ciceri, Lisa M Wodicka, Gabriel Pallares, Michael Hocker, Daniel K Treiber, Patrick P Zarrinkar

39) SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells (Nature Biotechnology) Sunday October 23rd 2011
Nicole C Dubois, April M Craft, Parveen Sharma, David A Elliott, Edouard G Stanley, Andrew G Elefanty, Anthony Gramolini, Gordon Keller

40) A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia (Nature Biotechnology) Sunday October 23rd 2011
Lacramioara Ivanciu, Raffaella Toso, Paris Margaritis, Giulia Pavani, Haein Kim, Alexander Schlachterman, Jian-Hua Liu, Valerie Clerin, Debra D Pittman, Rosalind Rose-Miranda, Kathleen M Shields, David V Erbe, James F Tobin, Valder R Arruda, Rodney M Camire

41) Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing (Nature Biotechnology) Sunday October 23rd 2011
Samuel Myllykangas, Jason D Buenrostro, Georges Natsoulis, John M Bell, Hanlee P Ji

42) Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques (Nature Biotechnology) Sunday October 16th 2011
Guangmei Yan, Guojie Zhang, Xiaodong Fang, Yanfeng Zhang, Cai Li, Fei Ling, David N Cooper, Qiye Li, Yan Li, Alain J van Gool, Hongli Du, Jiesi Chen, Ronghua Chen, Pei Zhang, Zhiyong Huang, John R Thompson, Yuhuan Meng, Yinqi Bai, Jufang Wang, Min Zhuo, Tao Wang, Ying Huang, Liqiong Wei, Jianwen Li, Zhiwen Wang, Haofu Hu, Pengcheng Yang, Liang Le, Peter D Stenson, Bo Li, Xiaoming Liu, Edward V Ball, Na An, Quanfei Huang, Yong Zhang, Wei Fan, Xiuqing Zhang, Yingrui Li, Wen Wang, Michael G Katze, Bing Su, Rasmus Nielsen, Huanming Yang, Jun Wang, Xiaoning Wang, Jian Wang

43) Therapeutic siRNA silencing in inflammatory monocytes in mice (Nature Biotechnology) Sunday October 9th 2011
Florian Leuschner, Partha Dutta, Rostic Gorbatov, Tatiana I Novobrantseva, Jessica S Donahoe, Gabriel Courties, Kang Mi Lee, James I Kim, James F Markmann, Brett Marinelli, Peter Panizzi, Won Woo Lee, Yoshiko Iwamoto, Stuart Milstein, Hila Epstein-Barash, William Cantley, Jamie Wong, Virna Cortez-Retamozo, Andita Newton, Kevin Love, Peter Libby, Mikael J Pittet, Filip K Swirski, Victor Koteliansky, Robert Langer, Ralph Weissleder, Daniel G Anderson, Matthias Nahrendorf

44) Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance (Nature Biotechnology) Sunday October 9th 2011
Bruce E Tabashnik, Fangneng Huang, Mukti N Ghimire, B Rogers Leonard, Blair D Siegfried, Murugesan Rangasamy, Yajun Yang, Yidong Wu, Linda J Gahan, David G Heckel, Alejandra Bravo, Mario Soberón

45) Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris (Nature Biotechnology) Sunday October 2nd 2011
Randy M Berka, Igor V Grigoriev, Robert Otillar, Asaf Salamov, Jane Grimwood, Ian Reid, Nadeeza Ishmael, Tricia John, Corinne Darmond, Marie-Claude Moisan, Bernard Henrissat, Pedro M Coutinho, Vincent Lombard, Donald O Natvig, Erika Lindquist, Jeremy Schmutz, Susan Lucas, Paul Harris, Justin Powlowski, Annie Bellemare, David Taylor, Gregory Butler, Ronald P de Vries, Iris E Allijn, Joost van den Brink, Sophia Ushinsky, Reginald Storms, Amy J Powell, Ian T Paulsen, Liam D H Elbourne, Scott E Baker, Jon Magnuson, Sylvie LaBoissiere, A John Clutterbuck, Diego Martinez, Mark Wogulis, Alfredo Lopez de Leon, Michael W Rey, Adrian Tsang

46) Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding (Nature Biotechnology) Sunday October 2nd 2011
Rong Lu, Norma F Neff, Stephen R Quake, Irving L Weissman

47) Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE (Nature Biotechnology) Sunday October 2nd 2011
Peng Qiu, Erin F Simonds, Sean C Bendall, Kenneth D Gibbs, Robert V Bruggner, Michael D Linderman, Karen Sachs, Garry P Nolan, Sylvia K Plevritis

48) Performance comparison of exome DNA sequencing technologies (Nature Biotechnology) Sunday September 25th 2011
Michael J Clark, Rui Chen, Hugo Y K Lam, Konrad J Karczewski, Rong Chen, Ghia Euskirchen, Atul J Butte, Michael Snyder

49) CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells (Nature Biotechnology) Sunday September 25th 2011
Fraser J Sim, Crystal R McClain, Steven J Schanz, Tricia L Protack, Martha S Windrem, Steven A Goldman

50) Efficient de novo assembly of single-cell bacterial genomes from short-read data sets (Nature Biotechnology) Sunday September 18th 2011
Hamidreza Chitsaz, Joyclyn L Yee-Greenbaum, Glenn Tesler, Mary-Jane Lombardo, Christopher L Dupont, Jonathan H Badger, Mark Novotny, Douglas B Rusch, Louise J Fraser, Niall A Gormley, Ole Schulz-Trieglaff, Geoffrey P Smith, Dirk J Evers, Pavel A Pevzner, Roger S Lasken

51) A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching (Nature Biotechnology) Sunday September 11th 2011
Tanja Brakemann, Andre C Stiel, Gert Weber, Martin Andresen, Ilaria Testa, Tim Grotjohann, Marcel Leutenegger, Uwe Plessmann, Henning Urlaub, Christian Eggeling, Markus C Wahl, Stefan W Hell, Stefan Jakobs

52) An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells (Nature Biotechnology) Sunday August 14th 2011
Chad Tang, Andrew S Lee, Jens-Peter Volkmer, Debashis Sahoo, Divya Nag, Adriane R Mosley, Matthew A Inlay, Reza Ardehali, Shawn L Chavez, Renee Reijo Pera, Barry Behr, Joseph C Wu, Irving L Weissman, Micha Drukker

53) Astrocytes from familial and sporadic ALS patients are toxic to motor neurons (Nature Biotechnology) Wednesday August 10th 2011
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust, Meghan Rao, Amy Eagle, Anja Kammesheidt, Ashley Christensen, Jerry R Mendell, Arthur H M Burghes, Brian K Kaspar

54) An unbiased genome-wide analysis of zinc-finger nuclease specificity (Nature Biotechnology) Sunday August 7th 2011
Richard Gabriel, Angelo Lombardo, Anne Arens, Jeffrey C Miller, Pietro Genovese, Christine Kaeppel, Ali Nowrouzi, Cynthia C Bartholomae, Jianbin Wang, Geoffrey Friedman, Michael C Holmes, Philip D Gregory, Hanno Glimm, Manfred Schmidt, Luigi Naldini, Christof von Kalle

55) Quantitative fluorescence imaging of protein diffusion and interaction in living cells (Nature Biotechnology) Sunday August 7th 2011
Jérémie Capoulade, Malte Wachsmuth, Lars Hufnagel, Michael Knop

56) A resource of vectors and ES cells for targeted deletion of microRNAs in mice (Nature Biotechnology) Sunday August 7th 2011
Haydn M Prosser, Hiroko Koike-Yusa, James D Cooper, Frances C Law, Allan Bradley

57) Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression (Nature Biotechnology) Sunday July 31st 2011
John R Prensner, Matthew K Iyer, O Alejandro Balbin, Saravana M Dhanasekaran, Qi Cao, J Chad Brenner, Bharathi Laxman, Irfan A Asangani, Catherine S Grasso, Hal D Kominsky, Xuhong Cao, Xiaojun Jing, Xiaoju Wang, Javed Siddiqui, John T Wei, Daniel Robinson, Hari K Iyer, Nallasivam Palanisamy, Christopher A Maher, Arul M Chinnaiyan

58) The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line (Nature Biotechnology) Sunday July 31st 2011
Xun Xu, Harish Nagarajan, Nathan E Lewis, Shengkai Pan, Zhiming Cai, Xin Liu, Wenbin Chen, Min Xie, Wenliang Wang, Stephanie Hammond, Mikael R Andersen, Norma Neff, Benedetto Passarelli, Winston Koh, H Christina Fan, Jianbin Wang, Yaoting Gui, Kelvin H Lee, Michael J Betenbaugh, Stephen R Quake, Iman Famili, Bernhard O Palsson, Jun Wang

59) Dissecting the genome of the polyploid crop oilseed rape by transcriptome sequencing (Nature Biotechnology) Sunday July 31st 2011
Ian Bancroft, Colin Morgan, Fiona Fraser, Janet Higgins, Rachel Wells, Leah Clissold, David Baker, Yan Long, Jinling Meng, Xiaowu Wang, Shengyi Liu, Martin Trick

60) Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly (Nature Biotechnology) Sunday July 24th 2011
Yingrui Li, Hancheng Zheng, Ruibang Luo, Honglong Wu, Hongmei Zhu, Ruiqiang Li, Hongzhi Cao, Boxin Wu, Shujia Huang, Haojing Shao, Hanzhou Ma, Fan Zhang, Shuijian Feng, Wei Zhang, Hongli Du, Geng Tian, Jingxiang Li, Xiuqing Zhang, Songgang Li, Lars Bolund, Karsten Kristiansen, Adam J de Smith, Alexandra I F Blakemore, Lachlan J M Coin, Huanming Yang, Jian Wang, Jun Wang

61) Bright and stable near-infrared fluorescent protein for in vivo imaging (Nature Biotechnology) Sunday July 17th 2011
Grigory S Filonov, Kiryl D Piatkevich, Li-Min Ting, Jinghang Zhang, Kami Kim, Vladislav V Verkhusha

62) Genetic engineering of human pluripotent cells using TALE nucleases (Nature Biotechnology) Thursday July 7th 2011
Dirk Hockemeyer, Haoyi Wang, Samira Kiani, Christine S Lai, Qing Gao, John P Cassady, Gregory J Cost, Lei Zhang, Yolanda Santiago, Jeffrey C Miller, Bryan Zeitler, Jennifer M Cherone, Xiangdong Meng, Sarah J Hinkley, Edward J Rebar, Philip D Gregory, Fyodor D Urnov, Rudolf Jaenisch

63) Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor (Nature Biotechnology) Sunday June 26th 2011
Nicolas Bisson, D Andrew James, Gordana Ivosev, Stephen A Tate, Ron Bonner, Lorne Taylor, Tony Pawson

64) Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument (Nature Biotechnology) Sunday June 26th 2011
Razvan Nutiu, Robin C Friedman, Shujun Luo, Irina Khrebtukova, David Silva, Robin Li, Lu Zhang, Gary P Schroth, Christopher B Burge

65) A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease (Nature Biotechnology) Sunday June 19th 2011
Terri A Addona, Xu Shi, Hasmik Keshishian, D R Mani, Michael Burgess, Michael A Gillette, Karl R Clauser, Dongxiao Shen, Gregory D Lewis, Laurie A Farrell, Michael A Fifer, Marc S Sabatine, Robert E Gerszten, Steven A Carr

66) A targeted proteomics–based pipeline for verification of biomarkers in plasma (Nature Biotechnology) Sunday June 19th 2011
Jeffrey R Whiteaker, Chenwei Lin, Jacob Kennedy, Liming Hou, Mary Trute, Izabela Sokal, Ping Yan, Regine M Schoenherr, Lei Zhao, Uliana J Voytovich, Karen S Kelly-Spratt, Alexei Krasnoselsky, Philip R Gafken, Jason M Hogan, Lisa A Jones, Pei Wang, Lynn Amon, Lewis A Chodosh, Peter S Nelson, Martin W McIntosh, Christopher J Kemp, Amanda G Paulovich

67) Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data (Nature Biotechnology) Wednesday June 1st 2011
Chaolin Zhang, Robert B Darnell

68) De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera) (Nature Biotechnology) Sunday May 29th 2011
Eman K Al-Dous, Binu George, Maryam E Al-Mahmoud, Moneera Y Al-Jaber, Hao Wang, Yasmeen M Salameh, Eman K Al-Azwani, Srinivasa Chaluvadi, Ana C Pontaroli, Jeremy DeBarry, Vincent Arondel, John Ohlrogge, Imad J Saie, Khaled M Suliman-Elmeer, Jeffrey L Bennetzen, Robert R Kruegger, Joel A Malek

69) Global gene disruption in human cells to assign genes to phenotypes by deep sequencing (Nature Biotechnology) Sunday May 29th 2011
Jan E Carette, Carla P Guimaraes, Irene Wuethrich, Vincent A Blomen, Malini Varadarajan, Chong Sun, George Bell, Bingbing Yuan, Markus K Muellner, Sebastian M Nijman, Hidde L Ploegh, Thijn R Brummelkamp

70) Specification of transplantable astroglial subtypes from human pluripotent stem cells (Nature Biotechnology) Sunday May 22nd 2011
Robert Krencik, Jason P Weick, Yan Liu, Zhi-Jian Zhang, Su-Chun Zhang

71) Autoantigen discovery with a synthetic human peptidome (Nature Biotechnology) Sunday May 22nd 2011
H Benjamin Larman, Zhenming Zhao, Uri Laserson, Mamie Z Li, Alberto Ciccia, M Angelica Martinez Gakidis, George M Church, Santosh Kesari, Emily M LeProust, Nicole L Solimini, Stephen J Elledge

72) Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell (Nature Biotechnology) Sunday May 15th 2011
Leslie Magtanong, Cheuk Hei Ho, Sarah L Barker, Wei Jiao, Anastasia Baryshnikova, Sondra Bahr, Andrew M Smith, Lawrence E Heisler, John S Choy, Elena Kuzmin, Kerry Andrusiak, Anna Kobylianski, Zhijian Li, Michael Costanzo, Munira A Basrai, Guri Giaever, Corey Nislow, Brenda Andrews, Charles Boone

73) Full-length transcriptome assembly from RNA-Seq data without a reference genome (Nature Biotechnology) Sunday May 15th 2011
Manfred G Grabherr, Brian J Haas, Moran Yassour, Joshua Z Levin, Dawn A Thompson, Ido Amit, Xian Adiconis, Lin Fan, Raktima Raychowdhury, Qiandong Zeng, Zehua Chen, Evan Mauceli, Nir Hacohen, Andreas Gnirke, Nicholas Rhind, Federica di Palma, Bruce W Birren, Chad Nusbaum, Kerstin Lindblad-Toh, Nir Friedman, Aviv Regev

74) Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants (Nature Biotechnology) Sunday May 8th 2011
Dalila Pinto, Katayoon Darvishi, Xinghua Shi, Diana Rajan, Diane Rigler, Tom Fitzgerald, Anath C Lionel, Bhooma Thiruvahindrapduram, Jeffrey R MacDonald, Ryan Mills, Aparna Prasad, Kristin Noonan, Susan Gribble, Elena Prigmore, Patricia K Donahoe, Richard S Smith, Ji Hyeon Park, Matthew E Hurles, Nigel P Carter, Charles Lee, Stephen W Scherer, Lars Feuk

75) Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm (Nature Biotechnology) Sunday April 24th 2011
Paul Wicks, Timothy E Vaughan, Michael P Massagli, James Heywood

76) Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells (Nature Biotechnology) Sunday April 24th 2011
Michal Rabani, Joshua Z Levin, Lin Fan, Xian Adiconis, Raktima Raychowdhury, Manuel Garber, Andreas Gnirke, Chad Nusbaum, Nir Hacohen, Nir Friedman, Ido Amit, Aviv Regev

77) Parallel on-chip gene synthesis and application to optimization of protein expression (Nature Biotechnology) Sunday April 24th 2011
Jiayuan Quan, Ishtiaq Saaem, Nicholas Tang, Siying Ma, Nicolas Negre, Hui Gong, Kevin P White, Jingdong Tian

78) Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells (Nature Biotechnology) Wednesday April 13th 2011
Deepa Subramanyam, Samy Lamouille, Robert L Judson, Jason Y Liu, Nathan Bucay, Rik Derynck, Robert Blelloch

79) Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction (Nature Biotechnology) Sunday April 10th 2011
Guo-Yun Chen, Xi Chen, Samantha King, Karen A Cavassani, Jiansong Cheng, Xincheng Zheng, Hongzhi Cao, Hai Yu, Jingyao Qu, Dexing Fang, Wei Wu, Xue-Feng Bai, Jin-Qing Liu, Shireen A Woodiga, Chong Chen, Lei Sun, Cory M Hogaboam, Steven L Kunkel, Pan Zheng, Yang Liu

80) Spatiotemporal manipulation of auxin biosynthesis in cotton ovule epidermal cells enhances fiber yield and quality (Nature Biotechnology) Sunday April 10th 2011
Mi Zhang, Xuelian Zheng, Shuiqing Song, Qiwei Zeng, Lei Hou, Demou Li, Juan Zhao, Yuan Wei, Xianbi Li, Ming Luo, Yuehua Xiao, Xiaoying Luo, Jinfa Zhang, Chengbin Xiang, Yan Pei

81) Systematic exploration of essential yeast gene function with temperature-sensitive mutants (Nature Biotechnology) Sunday March 27th 2011
Zhijian Li, Franco J Vizeacoumar, Sondra Bahr, Jingjing Li, Jonas Warringer, Frederick S Vizeacoumar, Renqiang Min, Benjamin VanderSluis, Jeremy Bellay, Michael DeVit, James A Fleming, Andrew Stephens, Julian Haase, Zhen-Yuan Lin, Anastasia Baryshnikova, Hong Lu, Zhun Yan, Ke Jin, Sarah Barker, Alessandro Datti, Guri Giaever, Corey Nislow, Chris Bulawa, Chad L Myers, Michael Costanzo, Anne-Claude Gingras, Zhaolei Zhang, Anders Blomberg, Kerry Bloom, Brenda Andrews, Charles Boone

82) Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes (Nature Biotechnology) Sunday March 20th 2011
Lydia Alvarez-Erviti, Yiqi Seow, HaiFang Yin, Corinne Betts, Samira Lakhal, Matthew J A Wood

83) Label-free quantification of membrane-ligand interactions using backscattering interferometry (Nature Biotechnology) Sunday March 13th 2011
Michael M Baksh, Amanda K Kussrow, Mauro Mileni, M G Finn, Darryl J Bornhop

84) Conversion of proteins into biofuels by engineering nitrogen flux (Nature Biotechnology) Sunday March 13th 2011
Yi-Xin Huo, Kwang Myung Cho, Jimmy G Lafontaine Rivera, Emma Monte, Claire R Shen, Yajun Yan, James C Liao

85) Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers (Nature Biotechnology) Sunday February 13th 2011
Yibo Ling, Terrence Pong, Christophoros C Vassiliou, Paul L Huang, Michael J Cima

86) Fluorescent peptides highlight peripheral nerves during surgery in mice (Nature Biotechnology) Sunday February 6th 2011
Michael A Whitney, Jessica L Crisp, Linda T Nguyen, Beth Friedman, Larry A Gross, Paul Steinbach, Roger Y Tsien, Quyen T Nguyen

87) A functionally characterized test set of human induced pluripotent stem cells (Nature Biotechnology) Thursday February 3rd 2011
Gabriella L Boulting, Evangelos Kiskinis, Gist F Croft, Mackenzie W Amoroso, Derek H Oakley, Brian J Wainger, Damian J Williams, David J Kahler, Mariko Yamaki, Lance Davidow, Christopher T Rodolfa, John T Dimos, Shravani Mikkilineni, Amy B MacDermott, Clifford J Woolf, Christopher E Henderson, Hynek Wichterle, Kevin Eggan

88) Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes (Nature Biotechnology) Sunday January 23rd 2011
Marcus Bantscheff, Carsten Hopf, Mikhail M Savitski, Antje Dittmann, Paola Grandi, Anne-Marie Michon, Judith Schlegl, Yann Abraham, Isabelle Becher, Giovanna Bergamini, Markus Boesche, Manja Delling, Birgit D?lfeld, Dirk Eberhard, Carola Huthmacher, Toby Mathieson, Daniel Poeckel, Val?e Reader, Katja Strunk, Gavain Sweetman, Ulrich Kruse, Gitte Neubauer, Nigel G Ramsden, Gerard Drewes

89) Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription (Nature Biotechnology) Wednesday January 19th 2011
Feng Zhang, Le Cong, Simona Lodato, Sriram Kosuri, George M Church, Paola Arlotta

90) Regulation of transcription by unnatural amino acids (Nature Biotechnology) Sunday January 16th 2011
Chang C Liu, Lei Qi, Charles Yanofsky, Adam P Arkin

91) Efficient mucosal vaccination mediated by the neonatal Fc receptor (Nature Biotechnology) Sunday January 16th 2011
Lilin Ye, Rongyu Zeng, Yu Bai, Derry C Roopenian, Xiaoping Zhu

92) Expression of therapeutic proteins after delivery of chemically modified mRNA in mice (Nature Biotechnology) Sunday January 9th 2011
Michael S D Kormann, G?er Hasenpusch, Manish K Aneja, Gabriela Nica, Andreas W Flemmer, Susanne Herber-Jonat, Marceline Huppmann, Lauren E Mays, Marta Illenyi, Andrea Schams, Matthias Griese, Iris Bittmann, Rupert Handgretinger, Dominik Hartl, Joseph Rosenecker, Carsten Rudolph

93) A TALE nuclease architecture for efficient genome editing (Nature Biotechnology) Wednesday December 22nd 2010
Jeffrey C Miller, Siyuan Tan, Guijuan Qiao, Kyle A Barlow, Jianbin Wang, Danny F Xia, Xiangdong Meng, David E Paschon, Elo Leung, Sarah J Hinkley, Gladys P Dulay, Kevin L Hua, Irina Ankoudinova, Gregory J Cost, Fyodor D Urnov, H Steve Zhang, Michael C Holmes, Lei Zhang, Philip D Gregory, Edward J Rebar

94) Whole-genome molecular haplotyping of single cells (Nature Biotechnology) Sunday December 19th 2010
H Christina Fan, Jianbin Wang, Anastasia Potanina, Stephen R Quake

95) Haplotype-resolved genome sequencing of a Gujarati Indian individual (Nature Biotechnology) Sunday December 19th 2010
Jacob O Kitzman, Alexandra P MacKenzie, Andrew Adey, Joseph B Hiatt, Rupali P Patwardhan, Peter H Sudmant, Sarah B Ng, Can Alkan, Ruolan Qiu, Evan E Eichler, Jay Shendure

96) Targeted integration in rat and mouse embryos with zinc-finger nucleases (Nature Biotechnology) Sunday December 12th 2010
Xiaoxia Cui, Diana Ji, Daniel A Fisher, Yumei Wu, David M Briner, Edward J Weinstein

97) Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells (Nature Biotechnology) Sunday December 12th 2010
Eirini P Papapetrou, Gabsang Lee, Nirav Malani, Manu Setty, Isabelle Riviere, Laxmi M S Tirunagari, Kyuichi Kadota, Shoshannah L Roth, Patricia Giardina, Agnes Viale, Christina Leslie, Frederic D Bushman, Lorenz Studer, Michel Sadelain

98) Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine (Nature Biotechnology) Sunday December 12th 2010
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian, Jing Wang, Li Zhang, Timothy J Looney, Baichen Zhang, Lucy A Godley, Leslie M Hicks, Bruce T Lahn, Peng Jin, Chuan He

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