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1) Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq (Nature Biotechnology) Monday August 1st 2016
Karen M Mann, Justin Y Newberg, Michael A Black, Devin J Jones, Felipe Amaya-Manzanares, Liliana Guzman-Rojas, Takahiro Kodama, Jerrold M Ward, Alistair G Rust, Louise van der Weyden, Christopher Chin Kuan Yew, Jill L Waters, Marco L Leung, Keith Rogers, Susan M Rogers, Leslie A McNoe, Luxmanan Selvanesan, Nicholas Navin, Nancy A Jenkins, Neal G Copeland, Michael B Mann

2) Engineered non-Mendelian inheritance of entire parental genomes in C. elegans (Nature Biotechnology) Monday August 1st 2016
Judith Besseling, Henrik Bringmann

3) Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies (Nature Biotechnology) Tuesday July 26th 2016
Daryl M Gohl, Pajau Vangay, John Garbe, Allison MacLean, Adam Hauge, Aaron Becker, Trevor J Gould, Jonathan B Clayton, Timothy J Johnson, Ryan Hunter, Dan Knights, Kenneth B Beckman

4) Genetic improvement of tomato by targeted control of fruit softening (Nature Biotechnology) Monday July 25th 2016
Selman Uluisik, Natalie H Chapman, Rebecca Smith, Mervin Poole, Gary Adams, Richard B Gillis, Tabot M D Besong, Judith Sheldon, Suzy Stiegelmeyer, Laura Perez, Nurul Samsulrizal, Duoduo Wang, Ian D Fisk, Ni Yang, Charles Baxter, Daniel Rickett, Rupert Fray, Barbara Blanco-Ulate, Ann L T Powell, Stephen E Harding, Jim Craigon, Jocelyn K C Rose, Eric A Fich, Li Sun, David S Domozych, Paul D Fraser, Gregory A Tucker, Don Grierson, Graham B Seymour

5) Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues (Nature Biotechnology) Monday July 25th 2016
Taeyun Ku, Justin Swaney, Jeong-Yoon Park, Alexandre Albanese, Evan Murray, Jae Hun Cho, Young-Gyun Park, Vamsi Mangena, Jiapei Chen, Kwanghun Chung

6) Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution (Nature Biotechnology) Monday July 25th 2016
Assaf Weiner, David Lara-Astiaso, Vladislav Krupalnik, Ohad Gafni, Eyal David, Deborah R Winter, Jacob H Hanna, Ido Amit

7) A recellularized human colon model identifies cancer driver genes (Nature Biotechnology) Tuesday July 12th 2016
Huanhuan Joyce Chen, Zhubo Wei, Jian Sun, Asmita Bhattacharya, David J Savage, Rita Serda, Yuri Mackeyev, Steven A Curley, Pengcheng Bu, Lihua Wang, Shuibing Chen, Leona Cohen-Gould, Emina Huang, Xiling Shen, Steven M Lipkin, Neal G Copeland, Nancy A Jenkins, Michael L Shuler

8) Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames (Nature Biotechnology) Tuesday July 12th 2016
Xue-hai Liang, Wen Shen, Hong Sun, Michael T Migawa, Timothy A Vickers, Stanley T Crooke

9) Canola engineered with a microalgal polyketide synthase-like system produces oil enriched in docosahexaenoic acid (Nature Biotechnology) Monday July 11th 2016
Terence A Walsh, Scott A Bevan, Daniel J Gachotte, Cory M Larsen, William A Moskal, P A Owens Merlo, Lyudmila V Sidorenko, Ronnie E Hampton, Virginia Stoltz, Dayakar Pareddy, Geny I Anthony, Pudota B Bhaskar, Pradeep R Marri, Lauren M Clark, Wei Chen, Patrick S Adu-Peasah, Steven T Wensing, Ross Zirkle, James G Metz

10) Large-scale phenome analysis defines a behavioral signature for Huntington's disease genotype in mice (Nature Biotechnology) Monday July 4th 2016
Vadim Alexandrov, Dani Brunner, Liliana B Menalled, Andrea Kudwa, Judy Watson-Johnson, Matthew Mazzella, Ian Russell, Melinda C Ruiz, Justin Torello, Emily Sabath, Ana Sanchez, Miguel Gomez, Igor Filipov, Kimberly Cox, Mei Kwan, Afshin Ghavami, Sylvie Ramboz, Brenda Lager, Vanessa C Wheeler, Jeff Aaronson, Jim Rosinski, James F Gusella, Marcy E MacDonald, David Howland, Seung Kwak

11) Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies (Nature Biotechnology) Monday July 4th 2016
Paul W Tillberg, Fei Chen, Kiryl D Piatkevich, Yongxin Zhao, Chih-Chieh (Jay) Yu, Brian P English, Linyi Gao, Anthony Martorell, Ho-Jun Suk, Fumiaki Yoshida, Ellen M DeGennaro, Douglas H Roossien, Guanyu Gong, Uthpala Seneviratne, Steven R Tannenbaum, Robert Desimone, Dawen Cai, Edward S Boyden

12) Quantitative comparison of DNA methylation assays for biomarker development and clinical applications (Nature Biotechnology) Tuesday June 28th 2016
Christoph Bock, Florian Halbritter, Francisco J Carmona, Sascha Tierling, Paul Datlinger, Yassen Assenov, Mar, Anke K Bergmann, Keith Booher, Florence Busato, Mihaela Campan, Christina Dahl, Christina M Dahmcke, Dinh Diep, Agust, Clarissa Gerhauser, Andrea Haake, Katharina Heilmann, Thomas Holcomb, Dianna Hussmann, Mitsuteru Ito, Ruth Kl, Martin Kreutz, Marta Kulis, Virginia Lopez, Shalima S Nair, Dirk S Paul, Nongluk Plongthongkum, Wenjia Qu, Ana C Queir, Frank Reinicke, Guido Sauter, Thorsten Schlomm, Aaron Statham, Clare Stirzaker, Ruslan Strogantsev, Roc, Kimberly Walter, Dieter Weichenhan, Daniel J Weisenberger, Stephan Beck, Susan J Clark, Manel Esteller, Anne C Ferguson-Smith, Mario F Fraga, Per Guldberg, Lise Lotte Hansen, Peter W Laird, Jos, Anders O H Nygren, Ralf Peist, Christoph Plass, David S Shames, Reiner Siebert, Xueguang Sun, J, J, Kun Zhang

13) Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells (Nature Biotechnology) Tuesday June 28th 2016
Benjamin P Kleinstiver, Shengdar Q Tsai, Michelle S Prew, Nhu T Nguyen, Moira M Welch, Jose M Lopez, Zachary R McCaw, Martin J Aryee, J Keith Joung

14) Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction (Nature Biotechnology) Tuesday June 28th 2016
Dylan Mooijman, Siddharth S Dey, Jean-Charles Boisset, Nicola Crosetto, Alexander van Oudenaarden

15) Wide field-of-view, multi-region, two-photon imaging of neuronal activity in the mammalian brain (Nature Biotechnology) Tuesday June 28th 2016
Jeffrey N Stirman, Ikuko T Smith, Michael W Kudenov, Spencer L Smith

16) Saturation analysis for whole-genome bisulfite sequencing data (Nature Biotechnology) Tuesday June 28th 2016
Emanuele Libertini, Simon C Heath, Rifat A Hamoudi, Marta Gut, Michael J Ziller, Javier Herrero, Agata Czyz, Victor Ruotti, Hendrik G Stunnenberg, Mattia Frontini, Willem H Ouwehand, Alexander Meissner, Ivo G Gut, Stephan Beck

17) A crowdsourcing approach for reusing and meta-analyzing gene expression data (Nature Biotechnology) Monday June 20th 2016
Naisha Shah, Yongjian Guo, Katherine V Wendelsdorf, Yong Lu, Rachel Sparks, John S Tsang

18) Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids (Nature Biotechnology) Saturday June 11th 2016
C, Alain Bruhat, Val, C, Julien Averous, Anne-Catherine Maurin, Laurent Parry, Florent Mesclon, Yuki Muranishi, Pierre Cordelier, Aline Meulle, Patrick Baril, Anh Do Thi, Philippe Ravassard, Jacques Mallet, Pierre Fafournoux

19) Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin (Nature Biotechnology) Saturday June 11th 2016
Rahul Palchaudhuri, Borja Saez, Jonathan Hoggatt, Amir Schajnovitz, David B Sykes, Tiffany A Tate, Agnieszka Czechowicz, Youmna Kfoury, FNU Ruchika, Derrick J Rossi, Gregory L Verdine, Michael K Mansour, David T Scadden

20) A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo (Nature Biotechnology) Saturday June 11th 2016
Jun Chu, Younghee Oh, Alex Sens, Niloufar Ataie, Hod Dana, John J Macklin, Tal Laviv, Erik S Welf, Kevin M Dean, Feijie Zhang, Benjamin B Kim, Clement Tran Tang, Michelle Hu, Michelle A Baird, Michael W Davidson, Mark A Kay, Reto Fiolka, Ryohei Yasuda, Douglas S Kim, Ho-Leung Ng, Michael Z Lin

21) An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy (Nature Biotechnology) Friday June 10th 2016
Marco Quarta, Jamie O Brett, Rebecca DiMarco, Antoine De Morree, Stephane C Boutet, Robert Chacon, Michael C Gibbons, Victor A Garcia, James Su, Joseph B Shrager, Sarah Heilshorn, Thomas A Rando

22) DNA-guided genome editing using the Natronobacterium gregoryi Argonaute (Nature Biotechnology) Friday June 10th 2016
Feng Gao, Xiao Z Shen, Feng Jiang, Yongqiang Wu, Chunyu Han

23) Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells (Nature Biotechnology) Friday June 10th 2016
Daesik Kim, Jungeun Kim, Junho K Hur, Kyung Wook Been, Sun-heui Yoon, Jin-Soo Kim

24) Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins (Nature Biotechnology) Friday June 10th 2016
Junho K Hur, Kyoungmi Kim, Kyung Wook Been, Gayoung Baek, Sunghyeok Ye, Junseok W Hur, Seuk-Min Ryu, Youn Su Lee, Jin-Soo Kim

25) A split horseradish peroxidase for the detection of intercellular protein (Nature Biotechnology) Wednesday June 1st 2016
Jeffrey D Martell, Masahito Yamagata, Thomas J Deerinck, S, Carolyn G Kwa, Mark H Ellisman, Joshua R Sanes, Alice Y Ting

26) Generation of knockout mice by Cpf1-mediated gene targeting (Nature Biotechnology) Wednesday June 1st 2016
Yongsub Kim, Seung-A Cheong, Jong Geol Lee, Sang-Wook Lee, Myeong Sup Lee, In-Jeoung Baek, Young Hoon Sung

27) Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch (Nature Biotechnology) Monday May 2nd 2016
Benjamin L Oakes, Dana C Nadler, Avi Flamholz, Christof Fellmann, Brett T Staahl, Jennifer A Doudna, David F Savage

28) CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes (Nature Biotechnology) Monday April 25th 2016
Bastiaan Evers, Katarzyna Jastrzebski, Jeroen P M Heijmans, Wipawadee Grernrum, Roderick L Beijersbergen, Rene Bernards

29) A pigeonpea gene confers resistance to Asian soybean rust in soybean (Nature Biotechnology) Monday April 25th 2016
Cintia G Kawashima, Gustavo Augusto Guimar, S, Dan MacLean, Doug R Cook, Burkhard Steuernagel, Jongmin Baek, Costas Bouyioukos, Bernardo do V A Melo, Gustavo Trist, Jamile Camargos de Oliveira, Gilda Rauscher, Shipra Mittal, Lisa Panichelli, Karen Bacot, Ebony Johnson, Geeta Iyer, Girma Tabor, Brande B H Wulff, Eric Ward, Gregory J Rairdan, Karen E Broglie, Gusui Wu, H Peter van Esse, Jonathan D G Jones, S

30) Rapid cloning of disease-resistance genes in plants using mutagenesis and sequence capture (Nature Biotechnology) Monday April 25th 2016
Burkhard Steuernagel, Sambasivam K Periyannan, Inmaculada Hern, Kamil Witek, Matthew N Rouse, Guotai Yu, Asyraf Hatta, Mick Ayliffe, Harbans Bariana, Jonathan D G Jones, Evans S Lagudah, Brande B H Wulff

31) Accelerated cloning of a potato late blight (Nature Biotechnology) Monday April 25th 2016
Kamil Witek, Florian Jupe, Agnieszka I Witek, David Baker, Matthew D Clark, Jonathan D G Jones

32) Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow (Nature Biotechnology) Tuesday April 19th 2016
Hanhui Ma, Li-Chun Tu, Ardalan Naseri, Maximiliaan Huisman, Shaojie Zhang, David Grunwald, Thoru Pederson

33) Characterizing genomic alterations in cancer by complementary functional associations (Nature Biotechnology) Tuesday April 19th 2016
Jong Wook Kim, Olga B Botvinnik, Omar Abudayyeh, Chet Birger, Joseph Rosenbluh, Yashaswi Shrestha, Mohamed E Abazeed, Peter S Hammerman, Daniel DiCara, David J Konieczkowski, Cory M Johannessen, Arthur Liberzon, Amir Reza Alizad-Rahvar, Gabriela Alexe, Andrew Aguirre, Mahmoud Ghandi, Heidi Greulich, Francisca Vazquez, Barbara A Weir, Eliezer M Van Allen, Aviad Tsherniak, Diane D Shao, Travis I Zack, Michael Noble, Gad Getz, Rameen Beroukhim, Levi A Garraway, Masoud Ardakani, Chiara Romualdi, Gabriele Sales, David A Barbie, Jesse S Boehm, William C Hahn, Jill P Mesirov, Pablo Tamayo

34) Energy- and carbon-efficient synthesis of functionalized small molecules in bacteria using non-decarboxylative Claisen condensation reactions (Nature Biotechnology) Tuesday April 19th 2016
Seokjung Cheong, James M Clomburg, Ramon Gonzalez

35) Sequencing wild and cultivated cassava and related species reveals extensive interspecific hybridization and genetic diversity (Nature Biotechnology) Monday April 18th 2016
Jessen V Bredeson, Jessica B Lyons, Simon E Prochnik, G Albert Wu, Cindy M Ha, Eric Edsinger-Gonzales, Jane Grimwood, Jeremy Schmutz, Ismail Y Rabbi, Chiedozie Egesi, Poasa Nauluvula, Vincent Lebot, Joseph Ndunguru, Geoffrey Mkamilo, Rebecca S Bart, Tim L Setter, Roslyn M Gleadow, Peter Kulakow, Morag E Ferguson, Steve Rounsley, Daniel S Rokhsar

36) Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases (Nature Biotechnology) Tuesday April 12th 2016
Rong Chen, Lisong Shi, J, Brian Naughton, Pamela Sklar, Jianguo Zhang, Hanlin Zhou, Lifeng Tian, Om Prakash, Mathieu Lemire, Patrick Sleiman, Wei-yi Cheng, Wanting Chen, Hardik Shah, Yulan Shen, Menachem Fromer, Larsson Omberg, Matthew A Deardorff, Elaine Zackai, Jason R Bobe, Elissa Levin, Thomas J Hudson, Leif Groop, Jun Wang, Hakon Hakonarson, Anne Wojcicki, George A Diaz, Lisa Edelmann, Eric E Schadt, Stephen H Friend

37) Superheroes of disease resistance (Nature Biotechnology) Monday April 11th 2016
Daniel MacArthur

38) Near-optimal probabilistic RNA-seq quantification (Nature Biotechnology) Monday April 4th 2016
Nicolas L Bray, Harold Pimentel, P, Lior Pachter

39) Integrated digital error suppression for improved detection of circulating tumor DNA (Nature Biotechnology) Saturday April 2nd 2016
Aaron M Newman, Alexander F Lovejoy, Daniel M Klass, David M Kurtz, Jacob J Chabon, Florian Scherer, Henning Stehr, Chih Long Liu, Scott V Bratman, Carmen Say, Li Zhou, Justin N Carter, Robert B West, George W Sledge Jr, Joseph B Shrager, Billy W Loo, Joel W Neal, Heather A Wakelee, Maximilian Diehn, Ash A Alizadeh

40) An injectable nanoparticle generator enhances delivery of cancer therapeutics (Nature Biotechnology) Monday March 14th 2016
Rong Xu, Guodong Zhang, Junhua Mai, Xiaoyong Deng, Victor Segura-Ibarra, Suhong Wu, Jianliang Shen, Haoran Liu, Zhenhua Hu, Lingxiao Chen, Yi Huang, Eugene Koay, Yu Huang, Jun Liu, Joe E Ensor, Elvin Blanco, Xuewu Liu, Mauro Ferrari, Haifa Shen

41) One-step fermentative production of poly(lactate-co-glycolate) from carbohydrates in Escherichia coli (Nature Biotechnology) Monday March 14th 2016
So Young Choi, Si Jae Park, Won Jun Kim, Jung Eun Yang, Hyuk Lee, Jihoon Shin, Sang Yup Lee

42) Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease (Nature Biotechnology) Monday March 14th 2016
Suk See De Ravin, Andreas Reik, Pei-Qi Liu, Linhong Li, Xiaolin Wu, Ling Su, Castle Raley, Narda Theobald, Uimook Choi, Alexander H Song, Andy Chan, Jocelynn R Pearl, David E Paschon, Janet Lee, Hannah Newcombe, Sherry Koontz, Colin Sweeney, David A Shivak, Kol A Zarember, Madhusudan V Peshwa, Philip D Gregory, Fyodor D Urnov, Harry L Malech

43) First, design for data sharing (Nature Biotechnology) Thursday March 3rd 2016
John Wilbanks, Stephen H Friend

44) High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines (Nature Biotechnology) Monday February 29th 2016
Channing Yu, Aristotle M Mannan, Griselda Metta Yvone, Kenneth N Ross, Yan-Ling Zhang, Melissa A Marton, Bradley R Taylor, Andrew Crenshaw, Joshua Z Gould, Pablo Tamayo, Barbara A Weir, Aviad Tsherniak, Bang Wong, Levi A Garraway, Alykhan F Shamji, Michelle A Palmer, Michael A Foley, Wendy Winckler, Stuart L Schreiber, Andrew L Kung, Todd R Golub

45) Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity (Nature Biotechnology) Monday February 22nd 2016
Janet Karpinski, Ilona Hauber, Jan Chemnitz, Carola Sch, Maciej Paszkowski-Rogacz, Deboyoti Chakraborty, Niklas Beschorner, Helga Hofmann-Sieber, Ulrike C Lange, Adam Grundhoff, Karl Hackmann, Evelin Schrock, Josephine Abi-Ghanem, M Teresa Pisabarro, Vineeth Surendranath, Axel Schambach, Christoph Lindner, Jan van Lunzen, Joachim Hauber, Frank Buchholz

46) Transcriptome-scale RNase-footprinting of RNA-protein complexes (Nature Biotechnology) Monday February 22nd 2016
Zhe Ji, Ruisheng Song, Hailiang Huang, Aviv Regev, Kevin Struhl

47) Inclusion of Strep-tag II in design of antigen receptors for T-cell immunotherapy (Nature Biotechnology) Monday February 22nd 2016
Lingfeng Liu, Daniel Sommermeyer, Alexandra Cabanov, Paula Kosasih, Tyler Hill, Stanley R Riddell

48) A 3D bioprinting system to produce human-scale tissue constructs with structural integrity (Nature Biotechnology) Monday February 15th 2016
Hyun-Wook Kang, Sang Jin Lee, In Kap Ko, Carlos Kengla, James J Yoo, Anthony Atala

49) Fast search of thousands of short-read sequencing experiments (Nature Biotechnology) Monday February 8th 2016
Brad Solomon, Carl Kingsford

50) Haplotyping germline and cancer genomes with high-throughput linked-read sequencing (Nature Biotechnology) Monday February 1st 2016
Grace X Y Zheng, Billy T Lau, Michael Schnall-Levin, Mirna Jarosz, John M Bell, Christopher M Hindson, Sofia Kyriazopoulou-Panagiotopoulou, Donald A Masquelier, Landon Merrill, Jessica M Terry, Patrice A Mudivarti, Paul W Wyatt, Rajiv Bharadwaj, Anthony J Makarewicz, Yuan Li, Phillip Belgrader, Andrew D Price, Adam J Lowe, Patrick Marks, Gerard M Vurens, Paul Hardenbol, Luz Montesclaros, Melissa Luo, Lawrence Greenfield, Alexander Wong, David E Birch, Steven W Short, Keith P Bjornson, Pranav Patel, Erik S Hopmans, Christina Wood, Sukhvinder Kaur, Glenn K Lockwood, David Stafford, Joshua P Delaney, Indira Wu, Heather S Ordonez, Susan M Grimes, Stephanie Greer, Josephine Y Lee, Kamila Belhocine, Kristina M Giorda, William H Heaton, Geoffrey P McDermott, Zachary W Bent, Francesca Meschi, Nikola O Kondov, Ryan Wilson, Jorge A Bernate, Shawn Gauby, Alex Kindwall, Clara Bermejo, Adrian N Fehr, Adrian Chan, Serge Saxonov, Kevin D Ness, Benjamin J Hindson, Hanlee P Ji

51) Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain (Nature Biotechnology) Monday February 1st 2016
Benjamin E Deverman, Piers L Pravdo, Bryan P Simpson, Sripriya Ravindra Kumar, Ken Y Chan, Abhik Banerjee, Wei-Li Wu, Bin Yang, Nina Huber, Sergiu P Pasca, Viviana Gradinaru

52) A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice (Nature Biotechnology) Monday February 1st 2016
Yang Yang, Lili Wang, Peter Bell, Deirdre McMenamin, Zhenning He, John White, Hongwei Yu, Chenyu Xu, Hiroki Morizono, Kiran Musunuru, Mark L Batshaw, James M Wilson

53) Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo (Nature Biotechnology) Monday February 1st 2016
Hao Yin, Chun-Qing Song, Joseph R Dorkin, Lihua J Zhu, Yingxiang Li, Qiongqiong Wu, Angela Park, Junghoon Yang, Sneha Suresh, Aizhan Bizhanova, Ankit Gupta, Mehmet F Bolukbasi, Stephen Walsh, Roman L Bogorad, Guangping Gao, Zhiping Weng, Yizhou Dong, Victor Koteliansky, Scot A Wolfe, Robert Langer, Wen Xue, Daniel G Anderson

54) High-throughput mapping of regulatory DNA (Nature Biotechnology) Monday January 25th 2016
Nisha Rajagopal, Sharanya Srinivasan, Kameron Kooshesh, Yuchun Guo, Matthew D Edwards, Budhaditya Banerjee, Tahin Syed, Bart J M Emons, David K Gifford, Richard I Sherwood

55) Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates (Nature Biotechnology) Monday January 25th 2016
Arturo J Vegas, Omid Veiseh, Joshua C Doloff, Minglin Ma, Hok Hei Tam, Kaitlin Bratlie, Jie Li, Andrew R Bader, Erin Langan, Karsten Olejnik, Patrick Fenton, Jeon Woong Kang, Jennifer Hollister-Locke, Matthew A Bochenek, Alan Chiu, Sean Siebert, Katherine Tang, Siddharth Jhunjhunwala, Stephanie Aresta-Dasilva, Nimit Dholakia, Raj Thakrar, Thema Vietti, Michael Chen, Josh Cohen, Karolina Siniakowicz, Meirigeng Qi, James McGarrigle, Stephen Lyle, David M Harlan, Dale L Greiner, Jose Oberholzer, Gordon C Weir, Robert Langer, Daniel G Anderson

56) Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA (Nature Biotechnology) Wednesday January 20th 2016
Christopher D Richardson, Graham J Ray, Mark A DeWitt, Gemma L Curie, Jacob E Corn

57) Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 (Nature Biotechnology) Monday January 18th 2016
John G Doench, Nicolo Fusi, Meagan Sullender, Mudra Hegde, Emma W Vaimberg, Katherine F Donovan, Ian Smith, Zuzana Tothova, Craig Wilen, Robert Orchard, Herbert W Virgin, Jennifer Listgarten, David E Root

58) Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9 (Nature Biotechnology) Monday January 18th 2016
Gozde Korkmaz, Rui Lopes, Alejandro P Ugalde, Ekaterina Nevedomskaya, Ruiqi Han, Ksenia Myacheva, Wilbert Zwart, Ran Elkon, Reuven Agami

59) Antisense oligonucleotide (Nature Biotechnology) Monday December 21st 2015
Tomoki T Nomakuchi, Frank Rigo, Isabel Aznarez, Adrian R Krainer

60) Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes (Nature Biotechnology) Monday December 21st 2015
J, Amit Zeisel, Zolt, Daniela Calvigioni, Yuchio Yanagawa, G, Sten Linnarsson, Tibor Harkany

61) Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines (Nature Biotechnology) Monday December 21st 2015
Jungseog Kang, Chien-Hsiang Hsu, Qi Wu, Shanshan Liu, Adam D Coster, Bruce A Posner, Steven J Altschuler, Lani F Wu

62) Synthetic long-read sequencing reveals intraspecies diversity in the human microbiome (Nature Biotechnology) Monday December 21st 2015
Volodymyr Kuleshov, Chao Jiang, Wenyu Zhou, Fereshteh Jahanbani, Serafim Batzoglou, Michael Snyder

63) Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq (Nature Biotechnology) Monday December 21st 2015
Cathryn R Cadwell, Athanasia Palasantza, Xiaolong Jiang, Philipp Berens, Qiaolin Deng, Marlene Yilmaz, Jacob Reimer, Shan Shen, Matthias Bethge, Kimberley F Tolias, Rickard Sandberg, Andreas S Tolias

64) Generation of serotonin neurons from human pluripotent stem cells (Nature Biotechnology) Monday December 21st 2015
Jianfeng Lu, Xuefei Zhong, Huisheng Liu, Ling Hao, Cindy Tzu-Ling Huang, Mohammad Amin Sherafat, Jeffrey Jones, Melvin Ayala, Lingjun Li, Su-Chun Zhang

65) A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae (Nature Biotechnology) Monday December 7th 2015
Andrew Hammond, Roberto Galizi, Kyros Kyrou, Alekos Simoni, Carla Siniscalchi, Dimitris Katsanos, Matthew Gribble, Dean Baker, Eric Marois, Steven Russell, Austin Burt, Nikolai Windbichler, Andrea Crisanti, Tony Nolan

66) The quantitative and condition-dependent Escherichia coli proteome (Nature Biotechnology) Monday December 7th 2015
Alexander Schmidt, Karl Kochanowski, Silke Vedelaar, Erik Ahrn, Benjamin Volkmer, Luciano Callipo, K, Manuel Bauer, Ruedi Aebersold, Matthias Heinemann

67) Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus (Nature Biotechnology) Monday December 7th 2015
Kristin M Whitworth, Raymond R R Rowland, Catherine L Ewen, Benjamin R Trible, Maureen A Kerrigan, Ada G Cino-Ozuna, Melissa S Samuel, Jonathan E Lightner, David G McLaren, Alan J Mileham, Kevin D Wells, Randall S Prather

68) Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity (Nature Biotechnology) Monday November 30th 2015
Matthew T Chang, Saurabh Asthana, Sizhi Paul Gao, Byron H Lee, Jocelyn S Chapman, Cyriac Kandoth, JianJiong Gao, Nicholas D Socci, David B Solit, Adam B Olshen, Nikolaus Schultz, Barry S Taylor

69) Mapping the effects of drugs on the immune system (Nature Biotechnology) Monday November 30th 2015
Brian A Kidd, Aleksandra Wroblewska, Mary R Boland, Judith Agudo, Miriam Merad, Nicholas P Tatonetti, Brian D Brown, Joel T Dudley

70) Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids (Nature Biotechnology) Tuesday November 17th 2015
Miriam Amiram, Adrian D Haimovich, Chenguang Fan, Yane-Shih Wang, Hans-Rudolf Aerni, Ioanna Ntai, Daniel W Moonan, Natalie J Ma, Alexis J Rovner, Seok Hoon Hong, Neil L Kelleher, Andrew L Goodman, Michael C Jewett, Dieter S, Jesse Rinehart, Farren J Isaacs

71) Safeguarding CRISPR-Cas9 gene drives in yeast (Nature Biotechnology) Tuesday November 17th 2015
James E DiCarlo, Alejandro Chavez, Sven L Dietz, Kevin M Esvelt, George M Church

72) Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors (Nature Biotechnology) Tuesday November 17th 2015
Jianbin Wang, Colin M Exline, Joshua J DeClercq, G Nicholas Llewellyn, Samuel B Hayward, Patrick Wai-Lun Li, David A Shivak, Richard T Surosky, Philip D Gregory, Michael C Holmes, Paula M Cannon

73) Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides (Nature Biotechnology) Tuesday November 17th 2015
Shisheng Sun, Punit Shah, Shadi Toghi Eshghi, Weiming Yang, Namita Trikannad, Shuang Yang, Lijun Chen, Paul Aiyetan, Naseruddin H, Zhen Zhang, Daniel W Chan, Hui Zhang

74) Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics (Nature Biotechnology) Tuesday November 17th 2015
Sung Il Park, Daniel S Brenner, Gunchul Shin, Clinton D Morgan, Bryan A Copits, Ha Uk Chung, Melanie Y Pullen, Kyung Nim Noh, Steve Davidson, Soong Ju Oh, Jangyeol Yoon, Kyung-In Jang, Vijay K Samineni, Megan Norman, Jose G Grajales-Reyes, Sherri K Vogt, Saranya S Sundaram, Kellie M Wilson, Jeong Sook Ha, Renxiao Xu, Taisong Pan, Tae-il Kim, Yonggang Huang, Michael C Montana, Judith P Golden, Michael R Bruchas, Robert W Gereau, John A Rogers

75) Affinity regression predicts the recognition code of nucleic acid (Nature Biotechnology) Tuesday November 17th 2015
Raphael Pelossof, Irtisha Singh, Julie L Yang, Matthew T Weirauch, Timothy R Hughes, Christina S Leslie

76) GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions (Nature Biotechnology) Monday November 2nd 2015
Judith Agudo, Albert Ruzo, Eun Sook Park, Robert Sweeney, Veronika Kana, Meng Wu, Yong Zhao, Dieter Egli, Miriam Merad, Brian D Brown

77) Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition (Nature Biotechnology) Monday November 2nd 2015
Benjamin P Kleinstiver, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Ved V Topkar, Zongli Zheng, J Keith Joung

78) A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs (Nature Biotechnology) Monday October 26th 2015
Jiho Choi, Soohyun Lee, William Mallard, Kendell Clement, Guidantonio Malagoli Tagliazucchi, Hotae Lim, In Young Choi, Francesco Ferrari, Alexander M Tsankov, Ramona Pop, Gabsang Lee, John L Rinn, Alexander Meissner, Peter J Park, Konrad Hochedlinger

79) Long-term culture and expansion of primary human hepatocytes (Nature Biotechnology) Monday October 26th 2015
Gahl Levy, David Bomze, Stefan Heinz, Sarada Devi Ramachandran, Astrid Noerenberg, Merav Cohen, Oren Shibolet, Ella Sklan, Joris Braspenning, Yaakov Nahmias

80) In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity (Nature Biotechnology) Monday October 26th 2015
Geoffrey M Lynn, Richard Laga, Patricia A Darrah, Andrew S Ishizuka, Alexandra J Balaci, Andr, Michal Pechar, Robert Pola, Michael Y Gerner, Ayako Yamamoto, Connor R Buechler, Kylie M Quinn, Margery G Smelkinson, Ondrej Vanek, Ryan Cawood, Thomas Hills, Olga Vasalatiy, Kathrin Kastenm, Joseph R Francica, Lalisa Stutts, Janine K Tom, Keun Ah Ryu, Aaron P Esser-Kahn, Tomas Etrych, Kerry D Fisher, Leonard W Seymour, Robert A Seder

81) A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells (Nature Biotechnology) Monday October 26th 2015
Alexander M Tsankov, Veronika Akopian, Ramona Pop, Sundari Chetty, Casey A Gifford, Laurence Daheron, Nadejda M Tsankova, Alexander Meissner

82) Comprehensive characterization of the Published Kinase Inhibitor Set (Nature Biotechnology) Monday October 26th 2015
Jonathan M Elkins, Vita Fedele, Marta Szklarz, Kamal R Abdul Azeez, Eidarus Salah, Jowita Mikolajczyk, Sergei Romanov, Nikolai Sepetov, Xi-Ping Huang, Bryan L Roth, Ayman Al Haj Zen, Denis Fourches, Eugene Muratov, Alex Tropsha, Joel Morris, Beverly A Teicher, Mark Kunkel, Eric Polley, Karen E Lackey, Francis L Atkinson, John P Overington, Paul Bamborough, Susanne M, Daniel J Price, Timothy M Willson, David H Drewry, Stefan Knapp, William J Zuercher

83) DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins (Nature Biotechnology) Monday October 19th 2015
Je Wook Woo, Jungeun Kim, Soon Il Kwon, Claudia Corval, Seung Woo Cho, Hyeran Kim, Sang-Gyu Kim, Sang-Tae Kim, Sunghwa Choe, Jin-Soo Kim

84) Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state (Nature Biotechnology) Monday October 12th 2015
Assaf Rotem, Oren Ram, Noam Shoresh, Ralph A Sperling, Alon Goren, David A Weitz, Bradley E Bernstein

85) Nephron organoids derived from human pluripotent stem cells model kidney development and injury (Nature Biotechnology) Monday October 12th 2015
Ryuji Morizane, Albert Q Lam, Benjamin S Freedman, Seiji Kishi, M Todd Valerius, Joseph V Bonventre

86) Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease (Nature Biotechnology) Monday October 5th 2015
James E Dahlman, Omar O Abudayyeh, Julia Joung, Jonathan S Gootenberg, Feng Zhang, Silvana Konermann

87) Subangstrom single-molecule measurements of motor proteins using a nanopore (Nature Biotechnology) Tuesday September 29th 2015
Ian M Derrington, Jonathan M Craig, Eric Stava, Andrew H Laszlo, Brian C Ross, Henry Brinkerhoff, Ian C Nova, Kenji Doering, Benjamin I Tickman, Mostafa Ronaghi, Jeffrey G Mandell, Kevin L Gunderson, Jens H Gundlach

88) A catalog of the mouse gut metagenome (Nature Biotechnology) Tuesday September 29th 2015
Liang Xiao, Qiang Feng, Suisha Liang, Si Brask Sonne, Zhongkui Xia, Xinmin Qiu, Xiaoping Li, Hua Long, Jianfeng Zhang, Dongya Zhang, Chuan Liu, Zhiwei Fang, Joyce Chou, Jacob Glanville, Qin Hao, Dorota Kotowska, Camilla Colding, Tine Rask Licht, Donghai Wu, Jun Yu, Joseph Jao Yiu Sung, Qiaoyi Liang, Junhua Li, Huijue Jia, Zhou Lan, Valentina Tremaroli, Piotr Dworzynski, H Bj, Fredrik B, Jo, Emmanuelle Le Chatelier, S Dusko Ehrlich, John C Lin, Manimozhiyan Arumugam, Jun Wang, Lise Madsen, Karsten Kristiansen

89) Improving folate (vitamin B9) stability in biofortified rice through metabolic engineering (Nature Biotechnology) Monday September 21st 2015
Dieter Blancquaert, Jeroen Van Daele, Simon Strobbe, Filip Kiekens, Sergei Storozhenko, Hans De Steur, Xavier Gellynck, Willy Lambert, Christophe Stove, Dominique Van Der Straeten

90) Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes (Nature Biotechnology) Tuesday September 15th 2015
Sachet A Shukla, Michael S Rooney, Mohini Rajasagi, Grace Tiao, Philip M Dixon, Michael S Lawrence, Jonathan Stevens, William J Lane, Jamie L Dellagatta, Scott Steelman, Carrie Sougnez, Kristian Cibulskis, Adam Kiezun, Nir Hacohen, Vladimir Brusic, Catherine J Wu, Gad Getz

91) Optogenetic control of endogenous Ca2+ channels in vivo (Nature Biotechnology) Monday September 14th 2015
Taeyoon Kyung, Sangkyu Lee, Jung Eun Kim, Taesup Cho, Hyerim Park, Yun-Mi Jeong, Dongkyu Kim, Anna Shin, Sungsoo Kim, Jinhee Baek, Jihoon Kim, Na Yeon Kim, Doyeon Woo, Sujin Chae, Cheol-Hee Kim, Hee-Sup Shin, Yong-Mahn Han, Daesoo Kim, Won Do Heo

92) Engineering pulmonary vasculature in decellularized rat and human lungs (Nature Biotechnology) Monday September 14th 2015
Xi Ren, Philipp T Moser, Sarah E Gilpin, Tatsuya Okamoto, Tong Wu, Luis F Tapias, Francois E Mercier, Linjie Xiong, Raja Ghawi, David T Scadden, Douglas J Mathisen, Harald C Ott

93) Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning (Nature Biotechnology) Monday September 14th 2015
Brian Cleary, Ilana Lauren Brito, Katherine Huang, Dirk Gevers, Terrance Shea, Sarah Young, Eric J Alm

94) De novo sequencing and variant calling with nanopores using PoreSeq (Nature Biotechnology) Thursday September 10th 2015
Tamas Szalay, Jene A Golovchenko

95) ConStrains identifies microbial strains in metagenomic datasets (Nature Biotechnology) Monday September 7th 2015
Chengwei Luo, Rob Knight, Heli Siljander, Mikael Knip, Ramnik J Xavier, Dirk Gevers

96) Massively parallel high-order combinatorial genetics in human cells (Nature Biotechnology) Monday August 17th 2015
Alan S L Wong, Gigi C G Choi, Allen A Cheng, Oliver Purcell, Timothy K Lu

97) High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics (Nature Biotechnology) Monday August 17th 2015
Sean J Humphrey, S Babak Azimifar, Matthias Mann

98) Overexpression of receptor-like kinase ERECTA improves thermotolerance in rice and tomato (Nature Biotechnology) Monday August 17th 2015
Hui Shen, Xiangbin Zhong, Fangfang Zhao, Yanmei Wang, Bingxiao Yan, Qun Li, Genyun Chen, Bizeng Mao, Jianjun Wang, Yangsheng Li, Guoying Xiao, Yuke He, Han Xiao, Jianming Li, Zuhua He

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Mitch Andre Garcia's Chem Feeds 2008-present

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