1) Analogues of Morphanthridine and the Tear Gas Dibenz[b,f][1,4]oxazepine (CR) as Extremely Potent Activators of the Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channel (Journal of Medicinal Chemistry) Wednesday September 1st 2010 2) Crystal Structures of HLA-A*0201 Complexed with Melan-A/MART-126(27L)-35 Peptidomimetics Reveal Conformational Heterogeneity and Highlight Degeneracy of T Cell Recognition (Journal of Medicinal Chemistry) Wednesday September 1st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 3) Effects of Conformational Restriction of 2-Amino-3-benzoylthiophenes on A1 Adenosine Receptor Modulation (Journal of Medicinal Chemistry) Wednesday September 1st 2010 4) Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase (Journal of Medicinal Chemistry) Tuesday August 31st 2010 5) Synthesis, Anti-Inflammatory Activity, and in Vitro Antitumor Effect of a Novel Class of Cyclooxygenase Inhibitors: 4-(Aryloyl)phenyl Methyl Sulfones (Journal of Medicinal Chemistry) Tuesday August 31st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 6) Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a Clinical p38α MAP Kinase Inhibitor for the Treatment of Inflammatory Diseases (Journal of Medicinal Chemistry) Tuesday August 31st 2010 7) Inhalation by Design: Novel Ultra-Long-Acting β2-Adrenoreceptor Agonists for Inhaled Once-Daily Treatment of Asthma and Chronic Obstructive Pulmonary Disease That Utilize a Sulfonamide Agonist Headgroup (Journal of Medicinal Chemistry) Tuesday August 31st 2010 8) 3′-Deoxy Phosphoramidate Dinucleosides as Improved Inhibitors of Hepatitis C Virus Subgenomic Replicon and NS5B Polymerase Activity (Journal of Medicinal Chemistry) Saturday August 28th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 9) Design, Synthesis, and Preliminary Biological Evaluation of New Isoform-Selective f-Current Blockers (Journal of Medicinal Chemistry) Friday August 27th 2010 10) Antitumor Agents. 280. Multidrug Resistance-Selective Desmosdumotin B Analogues (Journal of Medicinal Chemistry) Thursday August 26th 2010 11) Nonsteroidal Dissociated Glucocorticoid Agonists Containing Azaindoles as Steroid A-Ring Mimetics (Journal of Medicinal Chemistry) Wednesday August 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 12) Design, Synthesis, and Biological Evaluation of Halogenated N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: Discovery of an Isoform-Selective Small Molecule Phospholipase D2 Inhibitor (Journal of Medicinal Chemistry) Wednesday August 25th 2010 13) 4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles That Are Cytotoxic against Combretastatin A Resistant Tumor Cells and Vascular Disrupting in a Cisplatin Resistant Germ Cell Tumor Model (Journal of Medicinal Chemistry) Tuesday August 24th 2010 14) Small-Molecule Inhibitors of NADPH Oxidase 4 (Journal of Medicinal Chemistry) Tuesday August 24th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 15) A Focused Library of Protein Tyrosine Phosphatase Inhibitors (Journal of Medicinal Chemistry) Tuesday August 24th 2010 16) Synthesis and Characterization of Novel Indole Derivatives Reveal Improved Therapeutic Agents for Treatment of Ischemia/Reperfusion (I/R) Injury (Journal of Medicinal Chemistry) Tuesday August 24th 2010 17) Potent and Fully Noncompetitive Peptidomimetic Inhibitor of Multidrug Resistance P-Glycoprotein (Journal of Medicinal Chemistry) Tuesday August 24th 2010 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 18) Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease (Journal of Medicinal Chemistry) Saturday August 21st 2010 19) Discovery of Mitogen-Activated Protein Kinase-Interacting Kinase 1 Inhibitors by a Comprehensive Fragment-Oriented Virtual Screening Approach (Journal of Medicinal Chemistry) Friday August 20th 2010 20) Design, Synthesis, and Evaluation of 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Derived, Redox-Sensitive Contrast Agents for Magnetic Resonance Imaging (Journal of Medicinal Chemistry) Friday August 20th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 21) Substituted 4-Carboxymethylpyroglutamic Acid Diamides as Potent and Selective Inhibitors of Fibroblast Activation Protein (Journal of Medicinal Chemistry) Thursday August 19th 2010 22) Toward Development of Targeted Nonsteroidal Antiandrogen-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid−Gadolinium Complex for Prostate Cancer Diagnostics (Journal of Medicinal Chemistry) Thursday August 19th 2010 23) (R,S)-anti-1-Amino-2-[18F]Fluorocyclopentyl-1-carboxylic Acid: Synthesis from Racemic 2-Benzyloxycyclopentanone and Biological Evaluation for Brain Tumor Imaging with Positron Emission Tomography (Journal of Medicinal Chemistry) Thursday August 19th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 24) Design and Synthesis of Potent “Sulfur-Free” Transition State Analogue Inhibitors of 5′-Methylthioadenosine Nucleosidase and 5′-Methylthioadenosine Phosphorylase (Journal of Medicinal Chemistry) Thursday August 19th 2010 25) Synthesis, Stereochemical Separation, and Biological Evaluation of Selective Inhibitors of Human MAO-B: 1-(4-Arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines (Journal of Medicinal Chemistry) Wednesday August 18th 2010 26) Design, Synthesis, and in Vitro Pharmacology of New Radiolabeled γ-Hydroxybutyric Acid Analogues Including Photolabile Analogues with Irreversible Binding to the High-Affinity γ-Hydroxybutyric Acid Binding Sites (Journal of Medicinal Chemistry) Wednesday August 18th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 27) Discovery of a Potent and Selective Noncovalent Linear Inhibitor of the Hepatitis C Virus NS3 Protease (BI 201335) (Journal of Medicinal Chemistry) Wednesday August 18th 2010 28) Discovery of Pyridazinopyridinones as Potent and Selective p38 Mitogen-Activated Protein Kinase Inhibitors (Journal of Medicinal Chemistry) Tuesday August 17th 2010 29) p-Trifluoromethyldiazirinyl-etomidate: A Potent Photoreactive General Anesthetic Derivative of Etomidate That Is Selective for Ligand-Gated Cationic Ion Channels (Journal of Medicinal Chemistry) Friday August 13th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 30) Interaction of Daunomycin with Acetylated Chromatin (Journal of Medicinal Chemistry) Wednesday August 11th 2010 31) Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase (Journal of Medicinal Chemistry) Wednesday August 11th 2010 32) Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses (Journal of Medicinal Chemistry) Tuesday August 10th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 33) Identification of CKD-516: A Potent Tubulin Polymerization Inhibitor with Marked Antitumor Activity against Murine and Human Solid Tumors (Journal of Medicinal Chemistry) Saturday August 7th 2010 34) Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus(1) (Journal of Medicinal Chemistry) Saturday August 7th 2010 35) Synthesis, in Vitro Activity, and Three-Dimensional Quantitative Structure−Activity Relationship of Novel Hydrazine Inhibitors of Human Vascular Adhesion Protein-1 (Journal of Medicinal Chemistry) Saturday August 7th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 36) Synthesis and Characterization of Nitroimidazole Derivatives for 68Ga-Labeling and Testing in Tumor Xenografted Mice (Journal of Medicinal Chemistry) Saturday August 7th 2010 37) Investigation of the Histamine H3 Receptor Binding Site. Design and Synthesis of Hybrid Agonists with a Lipophilic Side Chain (Journal of Medicinal Chemistry) Saturday August 7th 2010 38) Peptidyl α-Ketoamides with Nucleobases, Methylpiperazine, and Dimethylaminoalkyl Substituents as Calpain Inhibitors (Journal of Medicinal Chemistry) Saturday August 7th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 39) α,β-Unsaturated N-Acylpyrrole Peptidyl Derivatives: New Proteasome Inhibitors (Journal of Medicinal Chemistry) Friday August 6th 2010 40) Development of Potent Glucagon-like Peptide-1 Agonists with High Enzyme Stability via Introduction of Multiple Lactam Bridges (Journal of Medicinal Chemistry) Friday August 6th 2010 41) Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor (Journal of Medicinal Chemistry) Thursday August 5th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 42) Nonpeptidic and Potent Small-Molecule Inhibitors of cIAP-1/2 and XIAP Proteins (Journal of Medicinal Chemistry) Thursday August 5th 2010 43) Novel Carbamates as Orally Active Acetylcholinesterase Inhibitors Found to Improve Scopolamine-Induced Cognition Impairment: Pharmacophore-Based Virtual Screening, Synthesis, and Pharmacology† (Journal of Medicinal Chemistry) Thursday August 5th 2010 44) Synthesis, Structure−Activity Relationship, and Mode-of-Action Studies of Antimalarial Reversed Chloroquine Compounds (Journal of Medicinal Chemistry) Thursday August 5th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 45) Discovery of N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential (Journal of Medicinal Chemistry) Thursday August 5th 2010 46) Discovery of Pyrrole−Indoline-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile (Journal of Medicinal Chemistry) Wednesday August 4th 2010 47) Reverse Engineering Truncations of an Antimicrobial Peptide Dimer to Identify the Origins of Potency and Broad Spectrum of Action (Journal of Medicinal Chemistry) Wednesday August 4th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 48) Novel N-Methylated 8-Oxoisoguanines from Pacific Sponges with Diverse Neuroactivities (Journal of Medicinal Chemistry) Wednesday August 4th 2010 49) A New Class of Antitumor trans-Amine-Amidine-Pt(II) Cationic Complexes: Influence of Chemical Structure and Solvent on in Vitro and in Vivo Tumor Cell Proliferation (Journal of Medicinal Chemistry) Wednesday August 4th 2010 50) Strategies for Recognition of Stem−Loop RNA Structures by Synthetic Ligands: Application to the HIV-1 Frameshift Stimulatory Sequence (Journal of Medicinal Chemistry) Saturday July 31st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 51) Structure−Activity Relationships for a Novel Series of Citalopram (1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) Analogues at Monoamine Transporters (Journal of Medicinal Chemistry) Saturday July 31st 2010 52) Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy (Journal of Medicinal Chemistry) Saturday July 31st 2010 53) Discovery of Novel Cyanodihydropyridines as Potent Mineralocorticoid Receptor Antagonists (Journal of Medicinal Chemistry) Saturday July 31st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 54) Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series† (Journal of Medicinal Chemistry) Saturday July 31st 2010 55) [NiII(3-OMe-salophene)]: A Potent Agent with Antitumor Activity (Journal of Medicinal Chemistry) Friday July 30th 2010 56) Non-Peptide Macrocyclic Histone Deacetylase Inhibitors Derived from Tricyclic Ketolide Skeleton (Journal of Medicinal Chemistry) Friday July 30th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 57) Effects of 7-O Substitutions on Estrogenic and Anti-Estrogenic Activities of Daidzein Analogues in MCF-7 Breast Cancer Cells (Journal of Medicinal Chemistry) Friday July 30th 2010 58) Discovery and Mechanistic Study of a Class of Protein Arginine Methylation Inhibitors (Journal of Medicinal Chemistry) Thursday July 29th 2010 59) Aryl Phosphoramidates of 5-Phospho Erythronohydroxamic Acid, A New Class of Potent Trypanocidal Compounds (Journal of Medicinal Chemistry) Thursday July 29th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 60) Identification and Characterization of Acidic Mammalian Chitinase Inhibitors (Journal of Medicinal Chemistry) Thursday July 29th 2010 61) Synthesis and Antiproliferative Evaluation of Certain Indeno[1,2-c]quinoline Derivatives. Part 2 (Journal of Medicinal Chemistry) Thursday July 29th 2010 62) Novel Octreotide Dicarba-analogues with High Affinity and Different Selectivity for Somatostatin Receptors (Journal of Medicinal Chemistry) Thursday July 29th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 63) “Clicked” Bivalent Ligands Containing Curcumin and Cholesterol As Multifunctional Aβ Oligomerization Inhibitors: Design, Synthesis, and Biological Characterization (Journal of Medicinal Chemistry) Thursday July 29th 2010 64) Design, Synthesis, and Structure−Affinity Relationships of Regioisomeric N-Benzyl Alkyl Ether Piperazine Derivatives as σ-1 Receptor Ligands (Journal of Medicinal Chemistry) Thursday July 29th 2010 65) Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design (Journal of Medicinal Chemistry) Wednesday July 28th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 66) Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency (Journal of Medicinal Chemistry) Wednesday July 28th 2010 67) Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure−Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carboxamides as Highly Selective Cannabinoid-2 Receptor Ligands (Journal of Medicinal Chemistry) Wednesday July 28th 2010 68) Discovery of 2-[1-(4-Chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid (PSI-421), a P-Selectin Inhibitor with Improved Pharmacokinetic Properties and Oral Efficacy in Models of Vascular Injury (Journal of Medicinal Chemistry) Wednesday July 28th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 69) Improved Syntheses of 5′-S-(2-Aminoethyl)-6-N-(4-nitrobenzyl)-5′-thioadenosine (SAENTA), Analogues, and Fluorescent Probe Conjugates: Analysis of Cell-Surface Human Equilibrative Nucleoside Transporter 1 (hENT1) Levels for Prediction of the Antitumor Efficacy of Gemcitabine (Journal of Medicinal Chemistry) Saturday July 24th 2010 70) Effect of Synthetic Peptides Belonging to E2 Envelope Protein of GB Virus C on Human Immunodeficiency Virus Type 1 Infection (Journal of Medicinal Chemistry) Saturday July 24th 2010 71) Inhibition of Mycobacterial Replication by Pyrimidines Possessing Various C-5 Functionalities and Related 2′-Deoxynucleoside Analogues Using in Vitro and in Vivo Models (Journal of Medicinal Chemistry) Saturday July 24th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 72) Structural Optimization and Biological Evaluation of Substituted Bisphenol A Derivatives as β-Amyloid Peptide Aggregation Inhibitors (Journal of Medicinal Chemistry) Saturday July 24th 2010 73) Development and Characterization of New Inhibitors of the Human and Mouse Hematopoietic Prostaglandin D2 Synthases (Journal of Medicinal Chemistry) Saturday July 24th 2010 74) Computer-Aided Optimization of Phosphinic Inhibitors of Bacterial Ureases (Journal of Medicinal Chemistry) Saturday July 24th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 75) Synthesis and Biological Characterization of Novel Charge-Deficient Spermine Analogues (Journal of Medicinal Chemistry) Saturday July 24th 2010 76) Tetrahydroisoquinoline Derivatives As Highly Selective and Potent Rho Kinase Inhibitors (Journal of Medicinal Chemistry) Saturday July 24th 2010 77) Synthesis and Structure−Activity Relationships of Novel 8a-Aza-8a-homoerythromycin A Ketolides (Journal of Medicinal Chemistry) Saturday July 24th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 78) Crystal Structure-Based Selective Targeting of the Pyridoxal 5′-Phosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement (Journal of Medicinal Chemistry) Tuesday July 20th 2010 79) Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein (Journal of Medicinal Chemistry) Monday July 19th 2010 80) An Efficient Approach to the Discovery of Potent Inhibitors against Glycosyltransferases (Journal of Medicinal Chemistry) Monday July 19th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 81) Synthesis and Resolution of cis-(±)-Methyl (1R,2S/1S,2R)-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(±)-PPCC)]: New σ Receptor Ligands with Neuroprotective Effect (Journal of Medicinal Chemistry) Friday July 16th 2010 82) A Novel Water-Soluble Gossypol Derivative Increases Chemotherapeutic Sensitivity and Promotes Growth Inhibition in Colon Cancer (Journal of Medicinal Chemistry) Friday July 16th 2010 83) Replacement of Imidazolyl by Pyridyl in Biphenylmethylenes Results in Selective CYP17 and Dual CYP17/CYP11B1 Inhibitors for the Treatment of Prostate Cancer (Journal of Medicinal Chemistry) Friday July 16th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 84) Glucosylated Deferiprone and Its Brain Uptake: Implications for Developing Glucosylated Hydroxypyridinone Analogues Intended to Cross the Blood−Brain Barrier (Journal of Medicinal Chemistry) Friday July 16th 2010 85) Scaffold Hopping Using Two-Dimensional Fingerprints: True Potential, Black Magic, or a Hopeless Endeavor? Guidelines for Virtual Screening (Journal of Medicinal Chemistry) Friday July 16th 2010 86) Discovery of 6-(Aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as Potent, Selective Dipeptidyl Peptidase-4 (DPP4) Inhibitors (Journal of Medicinal Chemistry) Friday July 16th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 87) Identification of Orally Available Naphthyridine Protein Kinase D Inhibitors (Journal of Medicinal Chemistry) Friday July 16th 2010 88) Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D (Journal of Medicinal Chemistry) Friday July 16th 2010 89) Identification of the First Low-Molecular-Weight Inhibitors of Matriptase-2 (Journal of Medicinal Chemistry) Friday July 16th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 90) Biological Diversity from a Structurally Diverse Library: Systematically Scanning Conformational Space Using a Pyranose Scaffold† (Journal of Medicinal Chemistry) Friday July 16th 2010 91) Design, Synthesis, Enzyme-Inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors (Journal of Medicinal Chemistry) Friday July 16th 2010 92) The Sugar Ring of the Nucleoside Is Required for Productive Substrate Positioning in the Active Site of Human Deoxycytidine Kinase (dCK): Implications for the Development of dCK-Activated Acyclic Guanine Analogues (Journal of Medicinal Chemistry) Friday July 16th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 93) Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindol-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells(1) (Journal of Medicinal Chemistry) Friday July 16th 2010 94) Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists (Journal of Medicinal Chemistry) Thursday July 15th 2010 95) Design of Potent Inhibitors of Human RAD51 Recombinase Based on BRC Motifs of BRCA2 Protein: Modeling and Experimental Validation of a Chimera Peptide (Journal of Medicinal Chemistry) Thursday July 15th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 96) Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine2A Receptor Antagonists for the Treatment of Insomnia (Journal of Medicinal Chemistry) Thursday July 15th 2010 97) Understanding and Predicting Druggability. A High-Throughput Method for Detection of Drug Binding Sites (Journal of Medicinal Chemistry) Thursday July 15th 2010 98) Book Review of Computational Chemistry Workbook: Learning through Examples (Journal of Medicinal Chemistry) Thursday July 15th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote View: prev | next

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