1) Direct Construction of Imino-pyrrolidine-thione Scaffold via Isocyanide-Based Multicomponent Reaction (Journal of Combinatorial Chemistry) Tuesday August 31st 2010 2) Efficient Synthesis of Pyrazolopyrimidine Libraries (Journal of Combinatorial Chemistry) Tuesday August 31st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 2 Up Votes 3) Generation of Diverse 2H-Isoindol-1-ylphosphonates via Three-Component Reaction of 2-Alkynylbenzaldehyde, Aniline, and Phosphite (Journal of Combinatorial Chemistry) Thursday August 19th 2010 4) One-Pot Synthesis of Five and Six Membered N, O, S-Heterocycles Using a Ditribromide Reagent (Journal of Combinatorial Chemistry) Thursday August 19th 2010 5) Recycling the Versatile Pipecolic Linker (Journal of Combinatorial Chemistry) Wednesday August 18th 2010 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 6) Analysis of Protein−Small Molecule Interactions by Microscale Equilibrium Dialysis and Its Application As a Secondary Confirmation Method for on-Bead Screening† (Journal of Combinatorial Chemistry) Wednesday August 4th 2010 7) Efficient Assembly of 1-Methylene-1H-indenes via Palladium-Catalyzed Tandem Reaction of 1-(2,2-Dibromovinyl)-2-alkenylbenzene with Arylboronic Acid (Journal of Combinatorial Chemistry) Wednesday August 4th 2010 8) Dipeptidyl-Quinolone Derivatives Inhibit Hypoxia Inducible Factor-1α Prolyl Hydroxylases-1, -2, and -3 with Altered Selectivity (Journal of Combinatorial Chemistry) Thursday July 29th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 9) Novel Isocyanide-Based One-Pot Multicomponent Syntheses of Tetrahydrobenzo[b][1,4]oxazepine and Malonamide Derivatives (Journal of Combinatorial Chemistry) Wednesday July 28th 2010 10) Synthesis of 5-Carboxamide-oxazolines with a Passerini−Zhu/Staudinger−Aza−Wittig Two-Step Protocol (Journal of Combinatorial Chemistry) Wednesday July 28th 2010 11) Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones by Three-Component Coupling of Isatoic Anhydride, Amines, and Aldehydes Catalyzed by Magnetic Fe3O4 Nanoparticles in Water (Journal of Combinatorial Chemistry) Saturday July 24th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 12) Quick Access to Druglike Heterocycles: Facile Silver-Catalyzed One-Pot Multicomponent Synthesis of Aminoindolizines (Journal of Combinatorial Chemistry) Saturday July 24th 2010 13) Fluorous Tagged N-Hydroxy Phthalimide for the Parallel Synthesis of O-Aryloxyamines (Journal of Combinatorial Chemistry) Saturday July 24th 2010 14) Multidisciplinary Synthetic Approach for Rapid Combinatorial Library Synthesis of Triaza-Fluorenes (Journal of Combinatorial Chemistry) Saturday July 24th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 15) Novel and Efficient One-Step Parallel Synthesis of Dibenzopyranones via Suzuki−Miyaura Cross Coupling (Journal of Combinatorial Chemistry) Saturday July 24th 2010 16) Synthesis of Diheterocyclic Compounds Based on Triazolyl Methoxy Phenylquinazolines via a One-Pot Four-Component-Click Reaction (Journal of Combinatorial Chemistry) Tuesday July 20th 2010 17) Studies toward a Library of Tetrahydrofurans: Click and MCR Products of Mono- And Bis-Tetrahydrofurans (Journal of Combinatorial Chemistry) Friday July 9th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 18) Positional Scanning Peptide Libraries for Kinase Substrate Specificity Determinations: Straightforward and Reproducible Synthesis Using Pentafluorophenyl Esters (Journal of Combinatorial Chemistry) Thursday July 8th 2010 19) Regioselective Synthesis of Novel Spiropyrrolidines and Spirothiapyrrolizidines Through Multicomponent 1,3-Dipolar Cycloaddition Reaction of Azomethine Ylides (Journal of Combinatorial Chemistry) Thursday July 8th 2010 20) Jeffamine Derivatized TentaGel Beads and Poly(dimethylsiloxane) Microbead Cassettes for Ultrahigh-Throughput in Situ Releasable Solution-Phase Cell-Based Screening of One-Bead-One-Compound Combinatorial Small Molecule Libraries (Journal of Combinatorial Chemistry) Friday July 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 21) Synthesis of a Library of 5,6-Unsubstituted 1,4-Dihydropyridines Based on a One-Pot 4CR/Elimination Process and Their Application to the Generation of Structurally Diverse Fused Nitrogen Heterocycles (Journal of Combinatorial Chemistry) Friday July 2nd 2010 22) Novel, One-Pot, Three-Component Route to Indol-3-yl Substituted Spirooxindole Derivatives (Journal of Combinatorial Chemistry) Friday July 2nd 2010 23) One-Pot Synthesis of New Substituted 1,2,3,4-Tetrahydrocarbazoles via Petasis Reaction (Journal of Combinatorial Chemistry) Wednesday June 30th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 24) Solution Phase Synthesis of a Combinatorial Library of Chalcones and Flavones as Potent Cathepsin V Inhibitors (Journal of Combinatorial Chemistry) Saturday June 26th 2010 25) Combinatorial Approach to the Development of a Single Mass YVO4:Bi3+,Eu3+ Phosphor with Red and Green Dual Colors for High Color Rendering White Light-Emitting Diodes (Journal of Combinatorial Chemistry) Saturday June 19th 2010 26) Library of 1,4-Disubstituted 1,2,3-Triazole Analogs of Oxazolidinone RNA-Binding Agents (Journal of Combinatorial Chemistry) Friday June 18th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 27) Synthesis of Hexahydrobenzo[b]pyrimido[4,5-h][1,6]naphthyridines via an Intramolecular Hetero-Diels−Alder Reaction (Journal of Combinatorial Chemistry) Wednesday June 16th 2010 28) Efficient and Convenient Synthesis of Pyrrolo[1,2-a]quinazoline Derivatives with the Aid of Tin(II) Chloride (Journal of Combinatorial Chemistry) Tuesday June 15th 2010 29) Combinatorial Syntheses of Five-Membered Ring Heterocycles Using Carbon Disulfide and a Solid Support (Journal of Combinatorial Chemistry) Friday June 11th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 30) Simultaneous and Orthogonal Covalent Exchange Processes in Dynamic Combinatorial Libraries (Journal of Combinatorial Chemistry) Wednesday June 9th 2010 31) Microwave-Assisted Copper(II)-Catalyzed One-Pot Four-Component Synthesis of Multifunctionalized Dihydropyridines (Journal of Combinatorial Chemistry) Tuesday June 8th 2010 32) Novel Approach to 1,5-Benzodiazepine-2-ones Containing Peptoid Backbone via One-Pot Diketene-Based Ugi-4CR (Journal of Combinatorial Chemistry) Tuesday June 8th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 33) Solid-Phase Synthesis of N-Substituted Pyrrolidinone-Tethered N-Substituted Piperidines via Ugi Reaction (Journal of Combinatorial Chemistry) Tuesday June 8th 2010 34) One-Step Synthesis of Diarylpyrazolo[3,4-b]pyridines from Isoflavones (Journal of Combinatorial Chemistry) Saturday June 5th 2010 35) Pattern-Based Sensing with Metal−Dye Complexes: Sensor Arrays versus Dynamic Combinatorial Libraries (Journal of Combinatorial Chemistry) Thursday June 3rd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 36) One-Pot Synthesis of 4,6-Diaryl-2-oxo(imino)-1,2-dihydropyridine-3-carbonitrile a New Scaffold for p38α MAP Kinase Inhibition (Journal of Combinatorial Chemistry) Thursday June 3rd 2010 37) Construction of a Polyheterocyclic Benzopyran Library with Diverse Core Skeletons through Diversity-Oriented Synthesis Pathway (Journal of Combinatorial Chemistry) Wednesday June 2nd 2010 38) Efficient One-Pot Synthesis of Novel Spirooxindole Derivatives via Three-Component Reaction in Aqueous Medium (Journal of Combinatorial Chemistry) Wednesday June 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 39) Dynamic Covalent Chemistry of Disulfides Offers a Highly Efficient Synthesis of Diverse Benzofused Nitrogen−Sulfur Heterocycles in One Pot (Journal of Combinatorial Chemistry) Saturday May 29th 2010 40) Synthesis of Novel 8,9-Dihydro-5H-pyrimido[4,5-e][1,4]diazepin-7(6H)-ones (Journal of Combinatorial Chemistry) Friday May 28th 2010 41) Efficient Pallado-Catalyzed C6-(het)arylation of Imidazo[1,2-b][1,2,4,5]Tetrazines under Microwave Irradiations (Journal of Combinatorial Chemistry) Thursday May 27th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 42) Regioselective Synthesis and in Vitro Anticancer Activity of 4-Aza-podophyllotoxin Derivatives Catalyzed by l-Proline (Journal of Combinatorial Chemistry) Thursday May 27th 2010 43) Iodine-Promoted Domino Reaction Leading to N-Substituted 2-Aminoquinoline-3-carbonitriles under Microwave Irradiation (Journal of Combinatorial Chemistry) Saturday May 22nd 2010 44) Application of Response Surface Method using Rapid Screening, Support Vector Machine, and Multiple Regression on the Acidity and Activity of Si−Al−Zr Ternary Oxide (Journal of Combinatorial Chemistry) Saturday May 22nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 45) Automated Maskless Photolithography System for Peptide Microarray Synthesis on a Chip (Journal of Combinatorial Chemistry) Wednesday May 19th 2010 46) Combinatorial Optimization of (YxLu1−x−y)3Al5O12:Ce3y Green-Yellow Phosphors (Journal of Combinatorial Chemistry) Wednesday May 19th 2010 47) Approach to the Library of Fused Pyridine-4-carboxylic Acids by Combes-Type Reaction of Acyl Pyruvates and Electron-Rich Amino Heterocycles (Journal of Combinatorial Chemistry) Wednesday May 12th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 48) Exploration of Novel 2-Alkylimino-1,3-thiazolines: T-Type Calcium Channel Inhibitory Activity (Journal of Combinatorial Chemistry) Saturday May 8th 2010 49) One-Pot Combinatorial Synthesis of 4-Aryl-1H-thiopyrano[3,4-b]pyridine-5-one Derivatives (Journal of Combinatorial Chemistry) Thursday May 6th 2010 50) Synthetic Route for the Preparation of 2-Hydroxy-N-[1-(2-hydroxyphenylamino)-1-oxoalkan-2-yl]benzamides (Journal of Combinatorial Chemistry) Saturday May 1st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 51) Total Synthesis of (±)-Marinopyrrole A and Its Library as Potential Antibiotic and Anticancer Agents (Journal of Combinatorial Chemistry) Saturday May 1st 2010 52) Synthesis and Antitumor Evaluation of a Novel Class of 4-Substituted-1,4-Dihydroisoquinolin-3-ones (Journal of Combinatorial Chemistry) Thursday April 29th 2010 53) Diversity Oriented Synthesis of Pyrrolidines via Natural Carbohydrate Solid Acid Catalyst (Journal of Combinatorial Chemistry) Tuesday April 27th 2010 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 54) Rapid Automated Materials Synthesis Instrument: Exploring the Composition and Heat-Treatment of Nanoprecursors Toward Low Temperature Red Phosphors (Journal of Combinatorial Chemistry) Tuesday April 27th 2010 55) Design, Synthesis, and Diversification of 5,5-Dimethyl Cyclohexen-1,4-dione Library (Journal of Combinatorial Chemistry) Wednesday April 14th 2010 56) Metal-Free Synthesis of 2-Substituted (N, O, C) Benzothiazoles via an Intramolecular C−S Bond Formation (Journal of Combinatorial Chemistry) Saturday April 10th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 57) Diversity-Oriented Construction of Highly Substituted Indolizinones (Journal of Combinatorial Chemistry) Thursday April 1st 2010 58) Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: Selective Serotonin 5-HT6 Receptor Antagonists (Journal of Combinatorial Chemistry) Tuesday March 30th 2010 59) Fully Synthetic Phage-Like System for Screening Mixtures of Small Molecules in Live Cells (Journal of Combinatorial Chemistry) Saturday March 27th 2010 0 comments, related, 2 Up Votes 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 60) Tandem Reactions of N′-(2-Alkynylbenzylidene)hydrazides with Silyl Enolates: A Facile Route to H-Pyrazolo[5,1-a]isoquinolines (Journal of Combinatorial Chemistry) Friday March 26th 2010 61) Facile Method for the Combinatorial Synthesis of 2,2-Disubstituted Quinazolin-4(1H)-one Derivatives Catalyzed by Iodine in Ionic Liquids (Journal of Combinatorial Chemistry) Thursday March 25th 2010 62) Silica Gel-Promoted Tandem Addition−Cyclization Reactions of 2-Alkynylbenzenamines with Isothiocyanates (Journal of Combinatorial Chemistry) Thursday March 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 2 Up Votes 63) Synthesis of TiO2/WO3/MnO2 Composites and High-Throughput Screening for Their Photoelectrical Properties (Journal of Combinatorial Chemistry) Saturday March 13th 2010 64) Combinatorial Search for Iron/Titanium-Based Ternary Oxides with a Visible-Light Response (Journal of Combinatorial Chemistry) Saturday March 13th 2010 65) Synthesis of Chiral Polyaminothiazoles (Journal of Combinatorial Chemistry) Thursday March 11th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 66) Efficient Assembly of 2,5,6-Substituted Pyrimidines via MgI2-Mediated Morita−Baylis−Hillman Reaction (Journal of Combinatorial Chemistry) Thursday March 11th 2010 67) Efficient Solid-Phase Synthesis of a Series of Cyclic and Linear Peptoid−Dexamethasone Conjugates for the Cell Permeability Studies (Journal of Combinatorial Chemistry) Tuesday March 9th 2010 68) Novel Alkoxyamine Linker to Load Ketones for Solid-Phase Synthesis: Application of the Synthesis of 1,4-Benzodiazepine-2-ones (Journal of Combinatorial Chemistry) Saturday March 6th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 69) Parallel Solution Phase Synthesis of 3,6,7−4(3H)-Quinazolinones and Evaluation of Their Antitumor Activities against Human Cancer (Journal of Combinatorial Chemistry) Tuesday March 2nd 2010 70) Silica Gel-Mediated Amide Bond Formation: An Environmentally Benign Method for Liquid-Phase Synthesis and Cytotoxic Activities of Amides (Journal of Combinatorial Chemistry) Tuesday February 23rd 2010 71) Solid-Phase Peptide Synthesis of Endothelin Receptor Antagonists on Novel Flexible, Styrene−Acryloyloxyhydroxypropyl Methacrylate−Tripropyleneglycol Diacrylate [SAT] Resin (Journal of Combinatorial Chemistry) Monday February 22nd 2010 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 2 Up Votes 72) Parallel Synthesis of An Oligomeric Imidazole-4,5-dicarboxamide Library (Journal of Combinatorial Chemistry) Friday February 19th 2010 73) Regio- and Stereoselective Synthesis of Novel Dispiropyrrolidine Bisoxindole Derivatives via Multicomponent Reactions (Journal of Combinatorial Chemistry) Monday February 15th 2010 74) Nano-Combinatorial Chemistry Strategy for Nanotechnology Research (Journal of Combinatorial Chemistry) Thursday February 4th 2010 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 75) Microwave-Assisted Synthesis of Substituted 2-(Benzylthio)imidazo[1,2a]pyrimidin-5-ones (Journal of Combinatorial Chemistry) Thursday February 4th 2010 76) Simple and Catalyst-Free Synthesis of Oxoindolin-3-yl Phosphonates (Journal of Combinatorial Chemistry) Thursday January 28th 2010 77) Synthesis of Novel Substituted Benzimidazo[1,2-a]quinoxalin-6(5H)-ones via an Intramolecular Goldberg Reaction (Journal of Combinatorial Chemistry) Tuesday January 26th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 78) Synthesis of Zwitterionic Salts of Pyridinium-Meldrum Acid and Barbiturate through Unique Four-component Reactions (Journal of Combinatorial Chemistry) Friday January 22nd 2010 79) Efficient One-Pot Synthesis of Spirooxindole Derivatives Catalyzed by l-Proline in Aqueous Medium (Journal of Combinatorial Chemistry) Tuesday January 19th 2010 80) Synthesis and Application of a Microgel-Supported Acylating Reagent by Coupled Ring-Opening Metathesis Polymerization and Activators Re-Generated by Electron Transfer for Atom Transfer Radical Polymerization (Journal of Combinatorial Chemistry) Thursday January 14th 2010 0 comments, related, 1 Up Vote 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 81) Efficient and Highly Selective Method for the Synthesis of Benzo(naphtho)quinoline Derivatives Catalyzed by Iodine (Journal of Combinatorial Chemistry) Tuesday January 12th 2010 82) Synthesis of 1-(1H-Indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-Catalyzed Three-Component Reactions of 2-Alkynylbenzaldehydes, Amines, and Indoles (Journal of Combinatorial Chemistry) Friday January 8th 2010 83) Diverse Methyl Sulfone-Containing Benzo[b]thiophene Library via Iodocyclization and Palladium-Catalyzed Coupling (Journal of Combinatorial Chemistry) Thursday January 7th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 84) Fast Synthesis of N-Acylhydrazones Employing a Microwave Assisted Neat Protocol (Journal of Combinatorial Chemistry) Tuesday January 5th 2010 85) Concise Synthesis of 2, 3-Diarylpyrimido[1,2-a]benzimidazole Based on Isoflavones (Journal of Combinatorial Chemistry) Wednesday December 30th 2009 86) Tracking Chemical Processing Pathways in Combinatorial Polymer Libraries via Data Mining (Journal of Combinatorial Chemistry) Wednesday December 23rd 2009 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 87) Oriented Synthesis and In Vitro Anticancer Activity of Biquinazoline-2,2′-diones (Journal of Combinatorial Chemistry) Tuesday December 22nd 2009 88) Practical One-Pot Two-Step Protocol for the Microwave-Assisted Synthesis of Highly Functionalized Rhodanine Derivatives (Journal of Combinatorial Chemistry) Tuesday December 22nd 2009 89) Silica Gel-Catalyzed One-Pot Syntheses in Water and Fluorescence Properties Studies of 5-Amino-2-aryl-3H-chromeno[4,3,2-de][1,6]naphthyridine-4-carbonitriles and 5-Amino-2-aryl-3H-quinolino[4,3,2-de][1,6]naphthyridine-4-carbonitriles (Journal of Combinatorial Chemistry) Tuesday December 22nd 2009 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 3 Up Votes 90) Fluorous Synthesis of Substituted Sclerotigenin Library (Journal of Combinatorial Chemistry) Tuesday December 15th 2009 91) Making Mixtures to Solve Structures: Structural Elucidation via Combinatorial Synthesis (Journal of Combinatorial Chemistry) Tuesday December 15th 2009 92) Diversity-Oriented Synthesis of Quinolines via Friedländer Annulation Reaction under Mild Catalytic Conditions (Journal of Combinatorial Chemistry) Friday December 11th 2009 0 comments, related, 2 Up Votes 0 comments, related, 1 Up Vote 0 comments, related, 2 Up Votes 93) Parallel Synthesis of Bis-heterocyclic Isoxazolylmethyl- and Isoxazolinylmethylpyrazoles (Journal of Combinatorial Chemistry) Wednesday December 9th 2009 94) Solid-Phase Synthesis and Chemical Properties of 2-(2-Amino/hydroxyethyl)-1-aryl-3,4-dihydropyrazino[1, 2-b]indazol-2-iums (Journal of Combinatorial Chemistry) Friday December 4th 2009 95) Solid-Phase Synthesis of Unsymmetrical trans-Stilbenes (Journal of Combinatorial Chemistry) Friday December 4th 2009 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 96) Cyanoacetamide MCR (III): Three-Component Gewald Reactions Revisited (Journal of Combinatorial Chemistry) Friday December 4th 2009 97) Synthesis of Pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones (Journal of Combinatorial Chemistry) Friday December 4th 2009 98) Diversity Oriented Synthesis of Benzoxanthene and Benzochromene Libraries via One-Pot, Three-Component Reactions and Their Anti-proliferative Activity (Journal of Combinatorial Chemistry) Wednesday December 2nd 2009 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote View: prev | next

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