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1) Synthesis of 4′-deoxy-4′-fluoro neamine and 4′-deoxy-4′-fluoro 4′-epi neamine (ChemMedComm) Tuesday April 15th 2014
Stephen Hanessian, Oscar M. Saavedra, Miguel A. Vilchis-Reyes, Ana M. Llaguno-Rueda

2) THE SYNTHESIS AND FUNCTIONAL EVALUATION OF A MITOCHONDRIA TARGETED HYDROGEN SULFIDE DONOR, 10-OXO-10-(4-(3-THIOXO-3H-1,2-DITHIOL-5-YL) PHENOXY) DECYL) TRIPHENYLPHOSPHONIUM BROMIDE (AP39) (ChemMedComm) Monday April 7th 2014
Sophie Le Trionairre, Alexis Perry, Bartosz Szczesny, Szabo Csaba, Paul Winyard, Jacqueline Whatmore, Mark E. Wood, Matt Whiteman

3) Synthesis, Antiribosomal and Antibacterial Activity of 4'-O-Glycopyranosyl Paromomycin Aminoglycoside Antibiotics (ChemMedComm) Monday April 7th 2014
Weiwei Chen, Takahiko Matsushita, Dimitri Shcherbakov, Heithem Boukari, Andrea Vasella, Erik Bottger, D Crich

4) Dimerization hot spots in the structure of human Hsp90 (ChemMedComm) Friday April 4th 2014
Giulio Rastelli

5) N1-Linked Melatonin Dimers as Bivalent Ligands Targeting Dimeric Melatonin Receptors (ChemMedComm) Friday April 4th 2014
Anne-Sophie Journe, Samy A.M. Habib, Bala R. Dodda, Mina N.F. Morcos, Mirna S. Sadek, Sarah A.A. Tadros, Paula Witt-Enderby, Ralf Jockers, Darius Paul Zlotos

6) A full conformational characterization of antiandrogen cortexolone-17α-propionate and related compounds through theoretical calculations and nuclear magnetic resonance spectroscopy (ChemMedComm) Friday April 4th 2014
Patrizia Ferraboschi, Laura Legnani, Giuseppe Celasco, Luigi Moro, Laura Ragonesi, Diego Colombo

7) Design and synthesis of membrane-targeting antibiotics: from peptides- to aminosugar-based antimicrobial cationic amphiphiles (ChemMedComm) Thursday April 3rd 2014
Ido M. Herzog, Micha Fridman

8) Elucidating structural features of an entirely carbohydrate cancer vaccine construct employing circular dichroism and fluorescent labeling (ChemMedComm) Tuesday April 1st 2014
Kevin R. Trabbic, Ravindra A. De Silva, Peter R. Andreana

9) Novel inhibitors of breast cancer relevant kinases Brk and HER2 (ChemMedComm) Monday March 31st 2014
Kazem Ahmed Mahmoud, Tom Wersig, Inna Slynko, Frank Totzke, Christoph Schachtele, Markus Oelze, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

10) Novel phthalimide derivatives with TNF-α and IL-1β expression inhibitory and apoptotic inducer properties (ChemMedComm) Friday March 28th 2014
Lucas Cunha Duarte Coelho, Marcos Verissimo de Oliveira Cardoso, Diogo Rodrigo Magalhaes Moreira, Paulo Andre Teixeira de Moraes Gomes, Gevanio Bezerra de Oliveira Filho, Suellen Melo Tiburcio Cavalcanti, Lucianna Rabelo Pessoa Siqueira, Miria de Oliveira Barbosa, Arsenio Rodrigues Oliveira, Elizabeth Fernanda de Oliveira Borba, Teresinha Goncalves Silva, Belinda Kaskow, Mahdad Karimi, Lawrence J Abraham, Ana Cristina Lima Leite

11) Discovery and SAR study of a sulfonamide hydroxamic acid inhibitor for the botulinum neurotoxin serotype A light chain (ChemMedComm) Friday March 28th 2014
Nicholas Salzameda, Alexander Burtea

12) Design of glycosyltransferase inhibitors targeting human O-GlcNAc Transferase (OGT) (ChemMedComm) Friday March 21st 2014
Shuai Wang, David L Shen, Dominique Lafont, Anne-Sophie Vercoutter-Edouart, Marlene Mortuaire, Yun Shi, Ofelia Maniti, Agnes Girard-Egrot, Tony Lefebvre, B Mario Pinto, David Vocadlo, Sebastien Vidal

13) Synthesis and Antimicrobial Activities of His(2-aryl)-Arg and Trp-His(2-aryl) Classes of Dipeptidomimetics (ChemMedComm) Friday March 21st 2014
Amit Mahindra, Krishna Kumar Sharma, Dinesh Rathore, Shabana Khan, Melissa Jacobs, R Jain

14) Synthesis of iminosugar derivatives presenting naphthyl and alkylamine interacting groups and binding to somatostatin receptors (ChemMedComm) Thursday March 20th 2014
Stephen Barron, Paul Murphy

15) Specific chemical changes leading to consistent potency increases in structurally diverse active compounds (ChemMedComm) Thursday March 20th 2014
Dilyana Dimova, Dagmar Stumpfe, J Bajorath

16) Discovery of small molecule inhibitors targeting the SUMO-SIM interaction using a protein interface consensus approach (ChemMedComm) Tuesday March 18th 2014
Arnout Voet, Akihiro Ito, Mikako Hirohama, Seiji Matsuoka, Naoya Tochio, Takanori Kigawa, Minoru Yoshida, Kam Y.J. Zhang

17) Scaffold hopping of potential anti-tumor agents by WEGA: a shape-based approach (ChemMedComm) Tuesday March 18th 2014
Hu Ge, Yu Wang, Wenxia Zhao, Wei Lin, Xin Yan, Jun Xu

18) Two diseases, one approach: multitarget drug discovery in Alzheimer's and neglected tropical diseases (ChemMedComm) Monday March 17th 2014
Federica Prati, Elisa Uliassi, Maria Laura Bolognesi

19) Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery. (ChemMedComm) Monday March 17th 2014
Gautam Patel, Norma Roncal, Patricia Lee, Susan Leed, Jessey Erath, Ana Rodriguez, Richard Sciotti, Michael Pollastri

20) Introduction of polar groups on the naphthalene scaffold of molecular tongs inhibiting wild-type and mutated HIV-1 protease dimerization (ChemMedComm) Monday March 17th 2014
Sandrine Ongeri, Roberto Fanelli, Ana-Sofia Ressurreicao, Laure Dufau, Jean-Louis Soulier, Anamaria Vidu, Nicolo Tonali, Guillaume Bernadat, Michele Reboud-Ravaux

21) Conformational Properties of Cholic Acid, a Lead Compound at the Crossroads of Bile Acid Inspired Drug Discovery. (ChemMedComm) Monday March 17th 2014
Antimo Gioiello, Francesco Venturoni, Sara Tamimi, Chiara Custodi, Roberto Pellicciari, Antonio Macchiarulo

22) Combretastatin A-4 Inspired Novel 2-Aryl-3-arylamino-imidazo-pyridines/pyrazines as Tubulin Polymerization Inhibitors, Antimitotic and Anticancer Agents (ChemMedComm) Monday March 17th 2014
Sankar Kumar Guchhait, Nitesh Sanghai, Vaibhav Jain, Ranjan Preet, Somnath Kandekar, Sarita Das, Neha Trivedi, Purusottam Mohapatra, Garima Priyadarshani, Maneesh Kashyap, Dipon Das, Shakti Ranjan Sathapathy, Sumit Siddharth, Chanakya N. Kundu, Prasad. V. Bharatam

23) Design, synthesis and biological evaluation of novel trimethylpyrazine-2-carbonyloxy-cinnamic acids as potent cardiovascular agents (ChemMedComm) Wednesday March 12th 2014
Hongfei Chen, Guoning Li, Peng Zhan, Hong Li, Shouxun Wang, Xinyong Liu

24) Sulfonium Ions as Inhibitors of the Mycobacterial Galactofuranosyltransferase GlfT2 (ChemMedComm) Wednesday March 12th 2014
Jing Li, Todd L Lowary

25) Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography (ChemMedComm) Friday March 7th 2014
Lucie Guetzoyan, Richard Ingham, Nikzad Nikbin, Julien Rossignol, Michael Wolling, Mark Baumert, Nicola A Burgess-Brown, Claire M Strain-Damerell, Leela Shrestha, Paul Brennan, Oleg Fedorov, Stefan Knapp, Steven V Ley

26) Synthesis and synergistic antimycobacterial screening of chlorpromazine and its metabolites (ChemMedComm) Wednesday March 5th 2014
Elizabeth M. Kigondu, Mathew Njoroge, Kawaljit Singh, Nicholas Njuguna, Digby F. Warner, Kelly Chibale

27) The Antimalarial Drug Atovaquone Binds to Saposin B with Comparable Affinity to Coenzyme Q10 (ChemMedComm) Wednesday March 5th 2014
Brian Phillip Huta, Allison Roberts, Elizabeth Waters, Vivian Yaci Yu, M Mehlenbacher, Fadi Bou-Abdallah, Robert P Doyle

28) Synthesis and biological evaluation of coumarin-1, 2, 3-triazole-dithiocarbamate hybrids as potent LSD1 inhibitors (ChemMedComm) Monday March 3rd 2014
Xian-Wei Ye, Yichao Zheng, Ying-Chao Duan, Meng-Meng Wang, Bin Yu, Jing-Li Ren, Jin-Lian Ma, En Zhang, Hong-Min Liu

29) Synthesis and evaluation of linear CuAAC-oligomerized antifreeze neo-glycopeptides (ChemMedComm) Friday February 28th 2014
Steffen van der Wal, Chantelle J. Capicciotti, Stamatia Rontogianni, Robert N Ben, R M J Liskamp

30) Synthesis, anticancer evaluation and docking study of vadimezan derivatives with carboxyl substitution (ChemMedComm) Friday February 21st 2014
Shi-Jie Zhang, Ding Zhi-Shan, Jiang Fu-Sheng, Ge Qiu-Fu, Guo Dian-Wu, Li Hai-Bo, WX Hu

31) α-Aminophosphonates as novel antileishmanial chemotypes: synthesis, biological evaluation, and CoMFA studies (ChemMedComm) Thursday February 20th 2014
Asit Chakraborti, Srikant Bhagat, Sanjeev K. Garg, Shweta Mishra, Preet Kamal, Sushma Singh

32) Synthesis and Antiviral Evaluation of 4'-(1,2,3-Triazol-1-yl)thymidines (ChemMedComm) Wednesday February 19th 2014
Sanjeev Kumar V. Vernekar, Li Qiu, Jeana Zacharias, Robert Geraghty, Zhengqiang Wang

33) Biological evaluation and molecular modelling of didanosine derivatives (ChemMedComm) Wednesday February 19th 2014
Soledad Ravetti, Cristian De Candia, Maria Soledad Gualdesi, Sandra Pampuro, Gabriela Turk, Mario Alfredo Quevedo, Cristina Margarita Brinon

34) Validation of host factors as novel targets against HIV infection (ChemMedComm) Monday February 17th 2014
Zeger Debyser, Belete Desmmie, Oliver Taltynov, Jonas Demeulemeester, Frauke Christ

35) Asp185 is likely to serve as the catalytic base in the enzymatic reaction of HIV-1 reverse transcriptase: QM/MM approach (ChemMedComm) Monday February 17th 2014
Thanyada Rungrotemongkol, Adrian John Mulholland, Supa Hannongbua

36) Multitarget-directed resveratrol derivatives: anti-cholinesterases, anti-β-amyloid aggregation and monoamine oxidase inhibition properties against Alzheimer's disease (ChemMedComm) Monday February 17th 2014
Long-Fei Pan, Xiao-Bing Wang, Sai-Sai Xie, Su-Yi Li, Ling-Yi Kong

37) Hydrogen Sulfide Donors in Research and Drug Development (ChemMedComm) Friday February 14th 2014
Choon-Hong Tan, Song Zhijian, Ng Meiying, Dai Weilu, Thilo Hagen, Philip Moore, Dejian Huang, Zheng-wei Lee, Lih-wen Deng

38) Chemical biology for target identification and validation (ChemMedComm) Wednesday February 12th 2014


39) Necrosulfonamide inhibits necroptosis by selectively targeting the mixed lineage kinase domain-like protein (ChemMedComm) Wednesday February 12th 2014
Daohong Liao, Liming Sun, Weilong Liu, Sudan He, Xiaodong Wang, Xiaoguang Lei

40) Effect of the 4′-substituted phenylalanine moiety of sansalvamide A peptide on antitumor activity (ChemMedComm) Wednesday February 12th 2014
Shouxin Liu, Yihua Yang, Cuiran Zhao, Jing Huang, Chunyu Han, Jianrong Han

41) Bicyclic imidazole-4-one derivatives: a new class of antagonists for the G protein-coupled orphan receptors GPR18 and GPR55 (ChemMedComm) Tuesday February 11th 2014
Viktor Rempel, Kerstin Atzler, Andrea Behrenswerth, Tadeus Karcz, Clara Schoeder, Sonja Hinz, Maria Kaleta, Dominik Thimm, Katarzyna Kononocicz, Christa E Muller

42) Towards bacterial adhesion-based therapeutics and detection methods (ChemMedComm) Tuesday February 11th 2014
Roland Pieters, Nuria Parera Pera

43) A Novel Approach to Identify Molecular Binding to Influenza Virus N5N1: Screening using Molecularly Imprinted Polymers (MIPs) (ChemMedComm) Tuesday February 11th 2014
Thipvaree Wangchareansak, Arunee Thitithanyanont, Daungmanee Chuakheaw, Matthew Paul Gleeson, Peter A Lieberzeit, Chak Sangma

44) Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: Anticancer activity evaluation and mode of action study (ChemMedComm) Tuesday February 11th 2014
Anuj Thakur, Sunny Manohar, Christian E Velez Gerena, Beatriz Zayas, Vineet Kumar, Sanjay Malhotra, Diwan S Rawat

45) Arene ruthenium(II) complexes induce S-phase arrest in MG-63 cells through stabilization of c-myc G-quadruplex DNA (ChemMedComm) Tuesday February 11th 2014
Cundong Fan, Qiong Wu, Tianfeng Chen, Yibo Zhang, Wen-Jie Zheng, Qi Wang, Mei Wen-Jie

46) 4-Chlorocolchicine derivatives bearing a thiourea side chain at the C-7 position as potent anticancer agents (ChemMedComm) Friday February 7th 2014
Hiroyuki Nishiyama, Masahiro Ono, Takuya Sugimoto, Toshio Sasai, Naoyuki Asakawa, Satoshi Ueno, Yoshitaka Tominaga, Takashi Yaegashi, Masato Nagaoka, Takeshi Matsuzaki, Noriyuki Kogure, Mariko Kitajima, Hiromitsu Takayama

47) The chemistry and biology of the alpha-ketoglutarate-dependent histone N(epsilon)-methyl-lysine demethylases. (ChemMedComm) Thursday February 6th 2014
Weiping Zheng, Yajun Huang

48) Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I (ChemMedComm) Thursday February 6th 2014
Yiqing Zhou, Tianlin Guo, Xitao Li, Yi Dong, Paul Galatsis, Douglas S. Johnson, Zhengying Pan

49) More than just GPCR Ligand: Structure-based Discovery of Thioridazine Derivatives as Pim-1 Kinase Inhibitors (ChemMedComm) Wednesday February 5th 2014
Wei Li, Xiaobo Wan, Fanqi Zeng, Yuting Xie, Yanli Wang, Wei Zhang, Li Li, Niu Huang

50) When Tight is too Tight: Dasatinib and its Lower Affinity Analogue for Profiling Kinase Inhibitors in a Three-Hybrid Split-luciferase System (ChemMedComm) Tuesday February 4th 2014
Indraneel Ghosh, Luca Ogunleye, Benjamin Jester, Ahmed Badran, Ping Wang, Alexander Riemen

51) Synthesis and Biological Evaluation of Substituted N-Alkylphenyl-3,5-Dinitrobenzamide Analogs as Anti-TB Agents (ChemMedComm) Friday January 31st 2014
Gurunadham Munagala, Kushalava Reddy Yempalla, Sravan Kumar Aithagani, Nitin Pal Kalia, Furqan Ali, Intzar Ali, Vikrant Singh Rajput, Chitra Rani, Reena Chib, Rukmankesh Mehra, Amit Nargotra, Inshad A Khan, Ram A Vishwakarma, Parvinder Pal Singh

52) Synthesis and anticancer activity evaluation of resveratrol-chalcone conjugates (ChemMedComm) Friday January 31st 2014
Deepak Kumar, K. Kranthi Raj, Sanjay Malhotra, DS Rawat

53) The structure based design of dual HDAC/BET inhibitors as novel epigenetic probes (ChemMedComm) Wednesday January 29th 2014
Stephen J. Atkinson, Peter E. Soden, Davina C. Angell, Marcus Bantscheff, Chun-wa Chung, Kathryn A. Giblin, Nicholas Smithers, Rebecca C. Furze, Laurie Gordon, Gerard Drewes, Inmaculada Rioja, Jason Witherington, Nigel J. Parr, Rab K. Prinjha

54) Multifunctional dendrimers modified with alpha-tocopheryl succinate for targeted cancer therapy (ChemMedComm) Wednesday January 29th 2014
Xiangyang Shi, Yun Zheng, Fanfan Fu, Mengen Zhang, Mingwu Shen, Meifang Zhu

55) Comparative Mode-of-Action Analysis Following Manual and Automated Phenotype Detection in Xenopus laevis (ChemMedComm) Wednesday January 29th 2014
Georgios Drakakis, Adam Hendry, Kimberley Hanson, Suzanne Brewerton, Mike Bodkin, David Evans, Grant Wheeler, Andreas Bender

56) Confocal Microscopy of Cytoplasmic Lipid Droplets in a Live Cancer Cell: Number, Polarity, Diffusion and Solvation Dynamics (ChemMedComm) Wednesday January 29th 2014
Rajdeep Chowdhury, Batakrishna Jana, Abhijit Saha, Surajit Ghosh, Kankan Bhattacharyya

57) Construction of phenoxazine ring containing nitro and sulfonic acid group leading to phenoxazine-3-sulfonamide derivatives: Their evaluation as novel and potential insulin secretagogues (ChemMedComm) Sunday January 26th 2014
Manojit Pal, Gangula Mohan Rao, Baru Vijaya Kumar, P. Naresh, Konda Sravya, Puchchakayala Goverdhan, Vandana Rathore, Girdhar Singh Deora, Seelam Venkata Reddy Reddy

58) 3,4,2'-trimethoxy-trans-stilbene - a potent CYP1B1 inhibitor (ChemMedComm) Thursday January 23rd 2014
Renata Mikstacka, Marcin Wierzchowski, Zbigniew Dutkiewicz, Agnieszka Gielara-Korzanska, Artur Korzanski, Anna Teubert, Stanislaw Sobiak, Wanda Baer-Dubowska

59) Structure-based drug design of chromone antagonists of the adenosine A2A receptor (ChemMedComm) Thursday January 23rd 2014
Stephen P. Andrews, Jonathan S. Mason, Edward Hurrell, Miles Congreve

60) New arginine substituted derivative of poly(allylamine hydrochloride) for heparin reversal (ChemMedComm) Thursday January 9th 2014
Kamil Kaminski, Bartlomiej Kalaska, Paulina Koczurkiewicz, Marta Michalik, Krzysztof Szczubialka, Andrzej Mogielnicki, Wlodzimierz Buczko, M Nowakowska

61) Biologically active binaphthol-scaffolded imidazolium salts (ChemMedComm) Thursday January 9th 2014
Marc Vidal, Claude-Rosny Elie, Shirley Campbell, Audrey Claing, Andreea R. Schmitzer

62) FP Tethering: a screening technique to rapidly identify compounds that disrupt protein-protein interactions (ChemMedComm) Thursday January 9th 2014
Jean Lodge, T. Justin Rettenmaier, Will Pomerantz, Jim Wells, Anna K K Mapp

63) Cytotoxic and antiviral nitrobenzoyl sesquiterpenoids from the marine-derived fungus Aspergillus ochraceus Jcma1F17 (ChemMedComm) Thursday January 9th 2014
Wei Fang, Xiuping Lin, Xuefeng Zhou, Junting Wan, Xin Lu, Bin Yang, Wen Ai, Ji Lin, Tianyu Zhang, Zhengchao Tu, Yonghong Liu

64) Bioactive prenylated phenyl derivatives derived from marine natural products: novel scaffold for the design of BACE inhibitors. (ChemMedComm) Thursday January 9th 2014
Javier Lopez-Ogalla, Esther Garcia-Palomero, Jorge Sanchez-Quesada, Laura Rubio, Elena Delgado, Pablo Garcia, Miguel Medina, Ana Castro, Pilar Munoz

65) Synthesis and Biological Evaluation of New Conformationally Restricted S-DABO Hybrids as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase (ChemMedComm) Thursday January 9th 2014
haiqiu wu, Christophe Pannecouque, zihong yan, wenxue chen, qiuqin he, Fen er Chen, Jan Balzarini, Dirk Daelemans, Erik De Clercq

66) Pre-miRNA expressing plasmid delivery for anti-cancer therapy (ChemMedComm) Wednesday January 8th 2014
Aharon Gedanken, Lena Benisvy Aharonovich, Ulyana Shimanovich, Ariel Bier, Noam Kronfeld, Gila kazimirsky, Nis Giladi, Chaya Brodie

67) Heterocycle-fused Lupane Triterpenoids Inhibit Leishmania donovani Amastigotes (ChemMedComm) Wednesday January 8th 2014
Raisa Haavikko, Abedelmajeed Nasereddin, Nina Sacerdoti-Sierra, Dmitry Kopelyanskiy, Sami Alakurtti, Mari Tikka, Charles L. Jaffe, Jari Yli-Kauhaluoma

68) Emerging classes of armed antibody therapeutics against cancer (ChemMedComm) Wednesday January 8th 2014
Dario Neri, Christian Hess, Dario Venetz

69) A new 18F-heteroaryltrifluoroborate radio-prosthetic with greatly enhanced stability that is labelled by 18F-19F-isotope exchange in good yield at high specific activity (ChemMedComm) Tuesday December 24th 2013
Z. Liu, N. Hundal-Jabal, M. Wong, D. Yapp, K.-S. Lin, F. Benard, D. M. Perrin

70) Synthesis of metergoline analogues and their evaluation as antiplasmodial agents (ChemMedComm) Tuesday December 24th 2013
Kawaljit Singh, Gurminder Kaur, Faith Mjambili, Peter J. Smith, Kelly Chibale

71) Design, Synthesis and Evaluation of N6-Substituted 2-Aminoadenosine-5'-N-methylcarboxamides as A3 Adenosine Receptor Agonists (ChemMedComm) Friday December 20th 2013
Shane Devine, Lauren May, Peter J. Scammells

72) Fragment growing to retain or alter the selectivity of anchored kinase hinge-binding fragments (ChemMedComm) Monday December 16th 2013
Charlotte Allen, Amanda Welford, Thomas Matthews, John Caldwell, Ian Collins

73) Bioluminescence: a versatile technique for imaging cellular and molecular features (ChemMedComm) Friday December 13th 2013
Miranda A. Paley, Jennifer A. Prescher

74) Synthesis and biological evaluation of novel quinoxalinone-based HIV-1 reverse transcriptase inhibitors (ChemMedComm) Wednesday December 11th 2013
Jie Zhou, Bailing Xu

75) Rapid profiling of protein kinase inhibitors by quantitative proteomics (ChemMedComm) Wednesday December 11th 2013
Martin Golkowski, Jennifer Brigham, B. Gayani Perera, Guillermo Romano, Dustin James Maly, Shao-En Ong

76) Discovery of BET bromodomain inhibitors and their role in target validation (ChemMedComm) Wednesday December 11th 2013
Stefan Knapp

77) Hedgehog Signalling Pathway Inhibitors as Cancer Suppressing Agents (ChemMedComm) Wednesday December 11th 2013
Adam McCluskey, Trieu Trinh, Eileen Mclaughlin

78) The Development of Thieno[2,3-b]pyridine Analogues as Anticancer Agents applying in silico methods (ChemMedComm) Wednesday December 11th 2013
John Arabshahi, Euphemia Leung, David Barker, Johannes Reynisson

79) Development of CBAP-BPyne, a probe for γ-secretase and presenilinase (ChemMedComm) Wednesday December 11th 2013
Natalya Gertsik, T. Eric Ballard, Christopher W. am Ende, Douglas S Johnson, Yueming LI

80) Microfluidic continuous-flow radiosynthesis of [18F]FPEB suitable for human PET imaging (ChemMedComm) Wednesday December 11th 2013
Steven H Liang, Daniel Yokell, Raul Jackson, Peter Rice, Ronald Callahan, Keith Johnson, David Alagille, Gilles Tamagnan, Lee Collier, Neil Vasdev

81) Discovery of Acrylonitrile-Based Small Molecules Active Against Haemonchus contortus (ChemMedComm) Wednesday December 11th 2013
Christopher Gordon, Lacey Hizartzidis, Mark Tarleton, Jennette Sakoff, Jayne Gilbert, Bronwyn Campbell, Robin Gasser, Adam McCluskey

82) Novel radioiodinated 1,3,4-oxadiazole derivatives with improved in vivo properties for SPECT imaging of β-amyloid plaques (ChemMedComm) Tuesday December 10th 2013
Hiroyuki Watanabe, Masahiro Ono, Hiroyuki Kimura, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hideo Saji

83) Affinity-based target identification for bioactive small molecules (ChemMedComm) Wednesday December 4th 2013
Makoto Kawatani, Hiroyuki Osada

84) Transformation of selective factor Xa inhibitor rivaroxaban to a dual factor Xa/thrombin inhibitor by modification of the morpholin-3-one moiety (ChemMedComm) Wednesday December 4th 2013
Danijel KIKELJ, Janez Ilas, Uros Trstenjak

85) In vitro anticancer activity and SAR studies of triazolyl aminoacyl(peptidyl) penicillins (ChemMedComm) Wednesday December 4th 2013
Patricia Cornier, Carina Delpiccolo, Florencia Mascali, Dora B. Boggian, Ernesto Mata, Mariano Cardenas, Viviana Blanck, LP Roguin

86) Design and synthesis of a novel series of N,4-diphenylpyrimidin-2-amine derivatives as potent and selective PI3Kγ inhibitors (ChemMedComm) Wednesday December 4th 2013
Fei Fang, Dong-Dong Li, Chang-Po Zhao, Jing-Ran Li, Jian Sun, Qian-Ru Du, Hai-Liang Zhu

87) 4-Aminocyclopentane-1,3-diols as Platforms for Diversity: Synthesis of a Screening Library (ChemMedComm) Monday December 2nd 2013
Vida Zohrabi-Kalantari, Felix Wilde, Renate Grunert, Patrick J Bednarski, Andreas Link

88) Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation (ChemMedComm) Monday December 2nd 2013
Dahvid Davda, Brent Martin

89) Matched molecular pairs derived by retrosynthetic fragmentation (ChemMedComm) Friday November 22nd 2013
Antonio de la Vega de Leon, Jurgen Bajorath

90) The effect of a thieno[2,3-b]pyridine PLC-γ inhibitor on proliferation, morphology, migration and cell cycle of breast cancer cells (ChemMedComm) Friday November 22nd 2013
Euphemia Leung, Joy Hung, David Barker, Johannes Reynisson

91) Improved synthesis of 4-/6-substituted 2 carboxy-1H-indole-3-propionic acid derivatives and structure-activity relationships as GPR17 agonists (ChemMedComm) Friday November 22nd 2013
Younis Baqi, Samer Alshaibani, Kirsten Ritter, Aliaa Abdelrahman, Andreas Spinrath, Evi Kostenis, Christa E Muller

92) Synthesis of new 13-diphenylalkyl analogues of berberine and elucidation of their base pair specificity and energetics of DNA binding (ChemMedComm) Friday November 22nd 2013
Debipreeta Bhowmik, Franco Buzzetti, Gaetano Fiorillo, Fabrizio Orzi, Tanjia Syeda, Paolo Lombardi, Gopinatha Kumar

93) Target validation using in-cell clickable imaging probes (ChemMedComm) Friday November 22nd 2013
Brahma Ghosh, Lyn H Jones

94) Synthesis and biological evaluation of 2-acetamidothiophene-3-carboxamide derivatives against Leishmania donovani (ChemMedComm) Thursday November 21st 2013
Sangmi Oh, Bosung Kwon, Sunju Kong, Gyongseon Yang, Nakyung Lee, Dawoon Han, Junghyun Goo, Jair Lage De Siqueira Neto, Lucio Freitas Junior, Michele Liuzzi, Jinhwa Lee, Rita Song

95) Self-assembled, Redox-sensitive, H-shaped Pegylated Methotrexate Conjugates with High Drug-carrying Capability for Intracellular Drug Delivery (ChemMedComm) Thursday November 21st 2013
Yong-yong Li, Chunyan Dong, Wen-juan Xie, Tianbin Ren, Hai-qing Dong

96) Identification of orally bioavailable small-molecule inhibitors of hematopoietic prostaglandin D2 synthase using X-ray fragment based drug discovery (ChemMedComm) Thursday November 21st 2013
Gordon Saxty, David Norton, Karen Affleck, Dave Clapham, Anne Cleasby, Joe Coyle, Philip Day, Martyn Frederickson, Ashley Hancock, Heather Hobbs, Jonathan Hutchinson, Joelle Le, Melanie Leveridge, Rachel McMenamin, Paul Mortenson, Lee Page, Caroline Richardson, Linda Russell, Emma Sherriff, Simon Teague, Sorif Uddin, Simon Hodgson

97) 2-Hydroxy-substituted cinnamic acids and acetanilides are selective growth inhibitors of Mycobacterium tuberculosis (ChemMedComm) Monday November 11th 2013
Juan D. Guzman, Parisa N. Mortazavi, Tulika Munshi, Dimitrios Evangelopoulos, Timothy D. McHugh, Simon Gibbons, John Malkinson, Sanjib Bhakta

98) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach (ChemMedComm) Thursday November 7th 2013
Roland Geyer, Patrick Igel, Melanie Kaske, Sigurd Elz, Armin Buschauer

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