1) Inhibitory Properties of the P1 Tyr Variant of Antithrombin (Biochemistry) Tuesday March 9th 2010 2) In Vitro Modulation of Cytochrome P450 Reductase Supported Indoleamine 2,3-Dioxygenase Activity by Allosteric Effectors Cytochrome b5 and Methylene Blue (Biochemistry) Tuesday March 9th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 3) Levodopa Deactivates Enzymes That Regulate Thiol−Disulfide Homeostasis and Promotes Neuronal Cell Death: Implications for Therapy of Parkinson’s Disease (Biochemistry) Saturday March 6th 2010 4) Pyrophosphate Activation in Hypoxanthine−Guanine Phosphoribosyltransferase with Transition State Analogue (Biochemistry) Saturday March 6th 2010 5) Cold Adaptation in DEAD-Box Proteins (Biochemistry) Friday March 5th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 6) A Rearrangement of the Guanosine-Binding Site Establishes an Extended Network of Functional Interactions in the Tetrahymena Group I Ribozyme Active Site (Biochemistry) Friday March 5th 2010 7) Kinetic Analysis of the Interaction of b/HLH/Z Transcription Factors Myc, Max, and Mad with Cognate DNA (Biochemistry) Friday March 5th 2010 8) Erratum: Effect of A and B Metal Ion Site Occupancy on Conformational Changes in an RB69 DNA Polymerase Ternary Complex (Biochemistry) Friday March 5th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 9) Structure of the 1,N2-Etheno-2′-deoxyguanosine Lesion in the 3′-G(εdG)T-5′ Sequence Opposite a One-Base Deletion (Biochemistry) Friday March 5th 2010 10) p90 Ribosomal S6 Kinase 2, a Novel GPCR Kinase, Is Required for Growth Factor-Mediated Attenuation of GPCR Signaling (Biochemistry) Wednesday March 3rd 2010 11) Binding of Adenosine-Based Ligands to the MjDim1 rRNA Methyltransferase: Implications for Reaction Mechanism and Drug Design (Biochemistry) Wednesday March 3rd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 12) Site-Specific Effects of Diselenide Bridges on the Oxidative Folding of a Cystine Knot Peptide, ω-Selenoconotoxin GVIA (Biochemistry) Wednesday March 3rd 2010 13) Substrate Specificity Determinants of the Methanogen Homoaconitase Enzyme: Structure and Function of the Small Subunit (Biochemistry) Wednesday March 3rd 2010 14) An RNA Aptamer with High Affinity and Broad Specificity for Zinc Finger Proteins (Biochemistry) Wednesday March 3rd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 15) Succinylphosphonate Esters Are Competitive Inhibitors of MenD That Show Active-Site Discrimination between Homologous α-Ketoglutarate-Decarboxylating Enzymes (Biochemistry) Wednesday March 3rd 2010 16) Characterization of the Colchicine Binding Site on Avian Tubulin Isotype βVI (Biochemistry) Wednesday March 3rd 2010 17) Highly Oriented Recombinant Glycosyltransferases: Site-Specific Immobilization of Unstable Membrane Proteins by Using Staphylococcus aureus Sortase A (Biochemistry) Tuesday March 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 18) Structural Analysis and Functional Implications of the Negative mTORC1 Regulator REDD1 (Biochemistry) Tuesday March 2nd 2010 19) Importance of Alanine at Position 178 in Proteorhodopsin for Absorption of Prevalent Ambient Light in the Marine Environment (Biochemistry) Tuesday March 2nd 2010 20) Molecular Level Interactions of S100A13 with Amlexanox: Inhibitor for Formation of the Multiprotein Complex in the Nonclassical Pathway of Acidic Fibroblast Growth Factor (Biochemistry) Tuesday March 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 21) Highly Efficient Chromatin Transcription Induced by Superhelically Curved DNA Segments: The Underlying Mechanism Revealed by a Yeast System (Biochemistry) Tuesday March 2nd 2010 22) A Thiolate Anion Buried within the Hydrocarbon Ruler Perturbs PagP Lipid Acyl Chain Selection (Biochemistry) Tuesday March 2nd 2010 23) Metabolic Depletion of Sphingolipids Impairs Ligand Binding and Signaling of Human Serotonin1A Receptors (Biochemistry) Tuesday March 2nd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 24) Direct Interaction of the Mouse Cytomegalovirus m152/gp40 Immunoevasin with RAE-1 Isoforms (Biochemistry) Monday March 1st 2010 25) Peroxynitrite-Mediated Oxidative Modifications of Complex II: Relevance in Myocardial Infarction (Biochemistry) Monday March 1st 2010 26) The Putative Na+/H+ Antiporter of Vibrio cholerae, Vc-NhaP2, Mediates the Specific K+/H+ Exchange in Vivo (Biochemistry) Monday March 1st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 27) Dependence of Catalytic Activity on Driving Force in Solution Assays and Protein Film Voltammetry: Insights from the Comparison of Nitrate Reductase Mutants (Biochemistry) Monday March 1st 2010 28) Molecular Basis of Activation of Endopeptidase Activity of Botulinum Neurotoxin Type E (Biochemistry) Monday March 1st 2010 29) De Novo Self-Assembling Collagen Heterotrimers Using Explicit Positive and Negative Design (Biochemistry) Monday March 1st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 30) Kinetic and Structural Analysis of Substrate Specificity in Two Copper Amine Oxidases from Hansenula polymorpha (Biochemistry) Monday March 1st 2010 31) Structural Basis for the Superior Activity of the Large Isoform of Snow Flea Antifreeze Protein (Biochemistry) Monday March 1st 2010 32) Engineered Rings of Mixed Yeast Lsm Proteins Show Differential Interactions with Translation Factors and U-Rich RNA (Biochemistry) Monday March 1st 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 33) Identification of Core Structural Residues in the Sequentially Diverse and Structurally Homologous Bcl-2 Family of Proteins (Biochemistry) Monday March 1st 2010 34) The Assembly of a Multisubunit Photosynthetic Membrane Protein Complex: A Site-Specific Spin Labeling EPR Spectroscopic Study of the PsaC Subunit in Photosystem I (Biochemistry) Friday February 26th 2010 35) Naturally Occurring Variability in the Envelope Glycoprotein of HIV-1 and Development of Cell Entry Inhibitors (Biochemistry) Friday February 26th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 36) Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin (Biochemistry) Thursday February 25th 2010 37) Parallel Multiplicative Target Screening against Divergent Bacterial Replicases: Identification of Specific Inhibitors with Broad Spectrum Potential (Biochemistry) Thursday February 25th 2010 38) Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain (Biochemistry) Thursday February 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 39) Role of Asparagine 510 in the Relative Timing of Substrate Bond Cleavages in the Reaction Catalyzed by Choline Oxidase (Biochemistry) Thursday February 25th 2010 40) Circular Permutation of Bacillus circulans Xylanase: A Kinetic and Structural Study (Biochemistry) Thursday February 25th 2010 41) Relationships among Visual Cycle Retinoids, Rhodopsin Phosphorylation, and Phototransduction in Mouse Eyes during Light and Dark Adaptation (Biochemistry) Thursday February 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 42) Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability (Biochemistry) Thursday February 25th 2010 43) Conformation-Dependent Formation of the G[8−5]U Intrastrand Cross-Link in 5-Bromouracil-Containing G-Quadruplex DNA Induced by UVA Irradiation (Biochemistry) Thursday February 25th 2010 44) Bovine Chymosin: A Computational Study of Recognition and Binding of Bovine κ-Casein (Biochemistry) Thursday February 25th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 45) Proton Affinity of the Oxyanion Hole in the Active Site of Ketosteroid Isomerase (Biochemistry) Thursday February 25th 2010 46) Kinetics of Mismatch Formation opposite Lesions by the Replicative DNA Polymerase from Bacteriophage RB69 (Biochemistry) Thursday February 25th 2010 47) Hinge Residue I174 Is Critical for Proper dNTP Selection by DNA Polymerase β (Biochemistry) Tuesday February 23rd 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 48) Structure and Function of the Universal Stress Protein TeaD and Its Role in Regulating the Ectoine Transporter TeaABC of Halomonas elongata DSM 2581T (Biochemistry) Monday February 22nd 2010 49) Investigation of Translocation, DNA Unwinding, and Protein Displacement by NS3h, the Helicase Domain from the Hepatitis C Virus Helicase (Biochemistry) Monday February 22nd 2010 50) Signal Transducer and Activator of Transcription 6 (STAT6) Is a Novel Interactor of Annexin A2 in Prostate Cancer Cells (Biochemistry) Saturday February 20th 2010 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote 0 comments, related, 1 Up Vote View: prev | next

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