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99) Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists (ACS Chemical Biology) Monday August 22nd 2016
David Rodri

100) A Small-Molecule Inhibitor of Lin28 (ACS Chemical Biology) Monday August 22nd 2016
Martina Roos, Ugo Prade

101) Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist (ACS Chemical Biology) Wednesday August 17th 2016
Ross W. Cheloha, Tomoyuki Watanabe, Thomas Dean, Samuel H. Gellman, Thomas J. Gardella

102) Development of an Optical Zn2+ Probe Based on a Single Fluorescent Protein (ACS Chemical Biology) Friday August 12th 2016
Yan Qin, Deanne W. Sammond, Esther Braselmann, Margaret C. Carpenter, Amy E. Palmer

103) Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase (ACS Chemical Biology) Thursday August 11th 2016
John G. Allen, Mirna Mujacic, Michael J. Frohn, Alex J. Pickrell, Paul Kodama, Dhanashri Bagal, Tisha San Miguel, E. Allen Sickmier, Steve Osgood, Aleksander Swietlow, Vivian Li, John B. Jordan, Ki-Won Kim, Anne-Marie C. Rousseau, Yong-Jae Kim, Seb Caille, Mike Achmatowicz, Oliver Thiel, Christopher H. Fotsch, Pranhitha Reddy, John D. McCarter

104) Engineering of New Pneumocandin Side-Chain Analogues from Glarea lozoyensis by Mutasynthesis and Evaluation of Their Antifungal Activity (ACS Chemical Biology) Wednesday August 10th 2016
Li Chen, Yan Li, Qun Yue, Anna Loksztejn, Kenichi Yokoyama, Edd A. Felix, Xingzhong Liu, Ningyan Zhang, Zhiqiang An, Gerald F. Bills

105) Binding Analysis of Methyl-CpG Binding Domain of MeCP2 and Rett Syndrome Mutations (ACS Chemical Biology) Monday August 8th 2016
Ye Yang, Tugba G. Kucukkal, Jing Li, Emil Alexov, Weiguo Cao

106) Selectivity in Small Molecule Splicing Modulation (ACS Chemical Biology) Monday August 8th 2016
Deepak Kumar, Manoj K. Kashyap, James J. La Clair, Reymundo Villa, Ide Spaanderman, Stephen Chien, Laura Z. Rassenti, Thomas J. Kipps, Michael D. Burkart, Januario E. Castro

107) HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine (ACS Chemical Biology) Friday August 5th 2016
Pornpun Aramsangtienchai, Nicole A. Spiegelman, Bin He, Seth P. Miller, Lunzhi Dai, Yingming Zhao, Hening Lin

108) Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway (ACS Chemical Biology) Friday August 5th 2016
Matthew D. DeMars, Fang Sheng, Sung Ryeol Park, Andrew N. Lowell, Larissa M. Podust, David H. Sherman

109) Partial In Vitro Reconstitution of an Orphan Polyketide Synthase Associated with Clinical Cases of Nocardiosis (ACS Chemical Biology) Friday August 5th 2016
James Kuo, Stephen R. Lynch, Corey W. Liu, Xirui Xiao, Chaitan Khosla

110) A Fluorescent Transport Assay Enables Studying AmpG Permeases Involved in Peptidoglycan Recycling and Antibiotic Resistance (ACS Chemical Biology) Friday August 5th 2016
G. Evan Perley-Robertson, Anuj K. Yadav, Judith L. Winogrodzki, Keith A. Stubbs, Brian L. Mark, David J. Vocadlo

111) IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors (ACS Chemical Biology) Friday August 5th 2016
Alexandra Cousido-Siah, Francesc X. Ruiz, Jindr

112) Mechanistic Insight into the Biosynthesis and Detoxification of Fumonisin Mycotoxins (ACS Chemical Biology) Thursday August 4th 2016
Kevin M. N. Burgess, Justin B. Renaud, Tim McDowell, Mark W. Sumarah

113) Improved Deconvolution of Protein Targets for Bioactive Compounds Using a Palladium Cleavable Chloroalkane Capture Tag (ACS Chemical Biology) Wednesday August 3rd 2016
Rachel Friedman Ohana, Sergiy Levin, Monika G. Wood, Kris Zimmerman, Melanie L. Dart, Marie K. Schwinn, Thomas A. Kirkland, Robin Hurst, H. Tetsuo Uyeda, Lance P. Encell, Keith V. Wood

114) 19F NMR-Guided Design of Glycomimetic Langerin Ligands (ACS Chemical Biology) Wednesday August 3rd 2016
Eike-Christian Wamhoff, Jonas Hanske, Lennart Schnirch, Jonas Aretz, Maurice Grube, Daniel Varo

115) Quadruplex-Flanking Stem Structures Modulate the Stability and Metal Ion Preferences of RNA Mimics of GFP (ACS Chemical Biology) Tuesday August 2nd 2016
Eman A. Ageely, Zachary J. Kartje, Kushal J. Rohilla, Christopher L. Barkau, Keith T. Gagnon

116) Fluorescence-Activated Cell Sorting of Human l-asparaginase Mutant Libraries for Detecting Enzyme Variants with Enhanced Activity (ACS Chemical Biology) Monday August 1st 2016
Christos S. Karamitros, Manfred Konrad

117) Single Cell Peptide Heterogeneity of Rat Islets of Langerhans (ACS Chemical Biology) Friday July 29th 2016
Erik T. Jansson, Troy J. Comi, Stanislav S. Rubakhin, Jonathan V. Sweedler

118) A Simple Molecular Rotor for Defining Nucleoside Environment within a DNA Aptamer (ACS Chemical Biology) Wednesday July 27th 2016
Thomas Z. Cservenyi, Abigail J. Van Riesen, Florence D. Berger, Ahmed Desoky, Richard A. Manderville

119) Specific Triacylglycerols Accumulate via Increased Lipogenesis During 5-FU-Induced Apoptosis (ACS Chemical Biology) Wednesday July 27th 2016
Nasi Li, Darleny Y. Lizardo, G. Ekin Atilla-Gokcumen

120) The Fungus Trichoderma Regulates Submerged Conidiation Using the Steroid Pregnenolone (ACS Chemical Biology) Friday July 22nd 2016
Hui Lin, Michael Travisano, Romas J. Kazlauskas

121) Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity (ACS Chemical Biology) Friday July 22nd 2016
Rebecca A. Kohnz, Lindsay S. Roberts, David DeTomaso, Lara Bideyan, Peter Yan, Sourav Bandyopadhyay, Andrei Goga, Nir Yosef, Daniel K. Nomura

122) Evolution of Src Homology 2 (SH2) Domain to Recognize Sulfotyrosine (ACS Chemical Biology) Thursday July 21st 2016
Tong Ju, Wei Niu, Jiantao Guo

123) Sequence-Specific Post-Synthetic Oligonucleotide Labeling for Single-Molecule Fluorescence Applications (ACS Chemical Biology) Thursday July 21st 2016
David Egloff, Igor A. Oleinich, Meng Zhao, Sebastian L. B. Ko

124) A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level (ACS Chemical Biology) Wednesday July 20th 2016
Anna Rutkowska, Douglas W. Thomson, Johanna Vappiani, Thilo Werner, Katrin M. Mueller, Lars Dittus, Jana Krause, Marcel Muelbaier, Giovanna Bergamini, Marcus Bantscheff

125) From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence (ACS Chemical Biology) Tuesday July 19th 2016
Sophie Mathieu, Cheickna Cisse

126) The Transmembrane Domain of a Bicomponent ABC Transporter Exhibits Channel-Forming Activity (ACS Chemical Biology) Tuesday July 19th 2016
Mohammad M. Mohammad, Noriko Tomita, Makoto Ohta, Liviu Movileanu

127) Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism (ACS Chemical Biology) Tuesday July 19th 2016
Kay Ahn, Markus Boehm, Matthew F. Brown, Jessica Calloway, Ye Che, Jinshan Chen, Kimberly F. Fennell, Kieran F. Geoghegan, Adam M. Gilbert, Jemy A. Gutierrez, Amit S. Kalgutkar, Adhiraj Lanba, Chris Limberakis, Thomas V. Magee, Inish O

128) Identification of Four Kinds of 2 (ACS Chemical Biology) Monday July 18th 2016
Ang Liu, Yang Yu, Qi Sheng, Xiao-Yu Zheng, Jin-Yu Yang, Ping-Yi Li, Mei Shi, Bai-Cheng Zhou, Yu-Zhong Zhang, Xiu-Lan Chen

129) A Genetically Encoded FRET Sensor for Hypoxia and Prolyl Hydroxylases (ACS Chemical Biology) Thursday July 14th 2016
Suzan Youssef, Wei Ren, Hui-wang Ai

130) Fingerprints of Calcium-Binding Protein Conformational Dynamics Monitored by Surface Plasmon Resonance (ACS Chemical Biology) Thursday July 14th 2016
Daniele Dell

131) EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor (ACS Chemical Biology) Thursday July 14th 2016
Eva De Mol, R. Bryn Fenwick, Christopher T. W. Phang, Victor Buzo

132) Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways (ACS Chemical Biology) Thursday July 14th 2016
Tyler D. Huber, Fengbin Wang, Shanteri Singh, Brooke R. Johnson, Jianjun Zhang, Manjula Sunkara, Steven G. Van Lanen, Andrew J. Morris, George N. Phillips, Jon S. Thorson

133) Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing (ACS Chemical Biology) Thursday July 14th 2016
Kimberly D. Barnash, Kelsey N. Lamb, Jacob I. Stuckey, Jacqueline L. Norris, Stephanie H. Cholensky, Dmitri B. Kireev, Stephen V. Frye, Lindsey I. James

134) Portability and Structure of the Four-Helix Bundle Docking Domains of trans-Acyltransferase Modular Polyketide Synthases (ACS Chemical Biology) Tuesday July 12th 2016
Jia Zeng, Drew T. Wagner, Zhicheng Zhang, Luisa Moretto, Janci D. Addison, Adrian T. Keatinge-Clay

135) Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase (ACS Chemical Biology) Monday July 11th 2016
Philipp M. Cromm, Jochen Spiegel, Philipp Ku

136) Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome (ACS Chemical Biology) Monday July 11th 2016
Wang-Yong Yang, Fang He, Rita L. Strack, Seok Yoon Oh, Michelle Frazer, Samie R. Jaffrey, Peter K. Todd, Matthew D. Disney

137) Semisynthetic and in Vitro Phosphorylation of Alpha-Synuclein at Y39 Promotes Functional Partly Helical Membrane-Bound States Resembling Those Induced by PD Mutations (ACS Chemical Biology) Monday July 11th 2016
Igor Dikiy, Bruno Fauvet, Ana Jovic

138) The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis (ACS Chemical Biology) Monday July 11th 2016
Weixin Tang, Gabrielle N. Thibodeaux, Wilfred A. van der Donk

139) Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis (ACS Chemical Biology) Thursday July 7th 2016
Xin Teng, Matthew J. Emmett, Mitchell A. Lazar, Erwin Goldberg, Joshua D. Rabinowitz

140) Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein (ACS Chemical Biology) Friday July 1st 2016
Rushikesh Sable, Thomas Durek, Veena Taneja, David J. Craik, Sandeep Pallerla, Ted Gauthier, Seetharama Jois

141) 17-OxoDHA Is a PPAR (ACS Chemical Biology) Friday July 1st 2016
Daichi Egawa, Toshimasa Itoh, Yui Akiyama, Tomoko Saito, Keiko Yamamoto

142) Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis (ACS Chemical Biology) Friday July 1st 2016
Bethany K. Okada, Yihan Wu, Dainan Mao, Leah B. Bushin, Mohammad R. Seyedsayamdost

143) Influence of Core (ACS Chemical Biology) Thursday June 30th 2016
Katarzyna Brzezicka, Uwe Vogel, Sonia Serna, Timo Johannssen, Bernd Lepenies, Niels-Christian Reichardt

144) Structural Basis of Selective Aromatic Pollutant Sensing by the Effector Binding Domain of MopR, an NtrC Family Transcriptional Regulator (ACS Chemical Biology) Thursday June 30th 2016
Shamayeeta Ray, Menachem J. Gunzburg, Matthew Wilce, Santosh Panjikar, Ruchi Anand

145) Structural and Functional Evidence Indicates Selective Oxygen Signaling in Caldanaerobacter subterraneus H-NOX (ACS Chemical Biology) Thursday June 30th 2016
Charles W. Hespen, Joel J. Bruegger, Christine M. Phillips-Piro, Michael A. Marletta

146) Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action (ACS Chemical Biology) Tuesday June 28th 2016
Gabriel Castro-Falco

147) Chemical Tools for Dissecting the Role of lncRNAs in Epigenetic Regulation (ACS Chemical Biology) Tuesday June 28th 2016
Sarah Nainar, Chao Feng, Robert C. Spitale

148) Albumin-Oxanorbornadiene Conjugates Formed ex Vivo for the Extended Circulation of Hydrophilic Cargo (ACS Chemical Biology) Tuesday June 28th 2016
Cody J. Higginson, Marsha R. Eno, Susan Khan, Michael D. Cameron, M.G. Finn

149) New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans (ACS Chemical Biology) Friday June 24th 2016
Matthew T. Henke, Alexandra A. Soukup, Anthony W. Goering, Ryan A. McClure, Regan J. Thomson, Nancy P. Keller, Neil L. Kelleher

150) Dark Hydrazone Fluorescence Labeling Agents Enable Imaging of Cellular Aldehydic Load (ACS Chemical Biology) Friday June 24th 2016
Lik Hang Yuen, Nivedita S. Saxena, Hyun Shin Park, Kenneth Weinberg, Eric T. Kool

151) Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases (ACS Chemical Biology) Friday June 24th 2016
Wei-Hung Chen, Kunhua Li, Naga Sandhya Guntaka, Steven D. Bruner

152) Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic Intermediates into an Essential Metabolite (ACS Chemical Biology) Friday June 24th 2016
Jennifer J. Thiaville, Jake Flood, Svetlana Yurgel, Laurence Prunetti, Mona Elbadawi-Sidhu, Geoffrey Hutinet, Farhad Forouhar, Xinshuai Zhang, Venkateswaran Ganesan, Patrick Reddy, Oliver Fiehn, J. A. Gerlt, John F. Hunt, Shelley D. Copley, Vale

153) Determination of the Specificity Landscape for Ribonuclease P Processing of Precursor tRNA 5 (ACS Chemical Biology) Friday June 24th 2016
Courtney N. Niland, Jing Zhao, Hsuan-Chun Lin, David R. Anderson, Eckhard Jankowsky, Michael E. Harris

154) Resistance Gene-Guided Genome Mining: Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic Pathway for Fellutamide B, a Proteasome Inhibitor (ACS Chemical Biology) Tuesday June 21st 2016
Hsu-Hua Yeh, Manmeet Ahuja, Yi-Ming Chiang, C. Elizabeth Oakley, Shauna Moore, Olivia Yoon, Heather Hajovsky, Jin-Woo Bok, Nancy P. Keller, Clay C. C. Wang, Berl R. Oakley

155) Harnessing Fluorine (ACS Chemical Biology) Tuesday June 21st 2016
Matthias R. Bauer, Rhiannon N. Jones, Matthias G. J. Baud, Rainer Wilcken, Frank M. Boeckler, Alan R. Fersht, Andreas C. Joerger, John Spencer

156) Characterization of the Post-Assembly Line Tailoring Processes in Teicoplanin Biosynthesis (ACS Chemical Biology) Tuesday June 21st 2016
Oleksandr Yushchuk, Bohdan Ostash, Thu H. Pham, Andriy Luzhetskyy, Victor Fedorenko, Andrew W. Truman, Liliya Horbal

157) Chemical Dimerizers in Three-Hybrid Systems for Small Molecule (ACS Chemical Biology) Tuesday June 21st 2016
Dries J. H. De Clercq, Jan Tavernier, Sam Lievens, Serge Van Calenbergh

158) 3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping (ACS Chemical Biology) Tuesday June 21st 2016
Yu-Chen Lo, Silvia Senese, Robert Damoiseaux, Jorge Z. Torres

159) In Vitro Biosynthesis and Substrate Tolerance of the Plantazolicin Family of Natural Products (ACS Chemical Biology) Thursday June 16th 2016
Caitlin D. Deane, Brandon J. Burkhart, Patricia M. Blair, Jonathan I. Tietz, Alice Lin, Douglas A. Mitchell

160) Rapid Inhibition Profiling in Bacillus subtilis to Identify the Mechanism of Action of New Antimicrobials (ACS Chemical Biology) Tuesday June 14th 2016
Anne Lamsa, Javier Lopez-Garrido, Diana Quach, Eammon P. Riley, Joe Pogliano, Kit Pogliano

161) Site-Specific Turn-On Fluorescent Labeling of DNA-Interacting Protein Using Oligodeoxynucleotides That Modify Lysines To Produce 5,6-Dimethoxy 3-Methyleneisoindolin-1-one (ACS Chemical Biology) Tuesday June 14th 2016
Chiemi Gatanaga, Bo Yang, Yuka Inadomi, Kazuteru Usui, Chiyoe Ota, Tsutomu Katayama, Hiroshi Suemune, Mariko Aso

162) An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription (ACS Chemical Biology) Monday June 13th 2016
David W. Crawford, Brett D. Blakeley, Po-Han Chen, Chringma Sherpa, Stuart F.J. Le Grice, Ite A. Laird-Offringa, Brian R. McNaughton

163) p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein (ACS Chemical Biology) Monday June 13th 2016
Stacie L. Bulfer, Tsui-Fen Chou, Michelle R. Arkin

164) Structural and Functional Analysis of the Allosteric Inhibition of IRE1 (ACS Chemical Biology) Thursday June 9th 2016
Hannah C. Feldman, Michael Tong, Likun Wang, Rosa Meza-Acevedo, Theodore A. Gobillot, Ivan Lebedev, Micah J. Gliedt, Sanjay B. Hari, Arinjay K. Mitra, Bradley J. Backes, Feroz R. Papa, Markus A. Seeliger, Dustin J. Maly

165) Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine (ACS Chemical Biology) Thursday June 9th 2016
Xiabin Chen, Xirong Zheng, Max Zhan, Ziyuan Zhou, Chang-Guo Zhan, Fang Zheng

166) In Cellulo Mapping of Subcellular Localized Bilirubin (ACS Chemical Biology) Wednesday June 8th 2016
Jong-Seok Park, Eunju Nam, Hye-Kyeong Lee, Mi Hee Lim, Hyun-Woo Rhee

167) N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells (ACS Chemical Biology) Tuesday June 7th 2016
Emmanuelle Thinon, Julia Morales-Sanfrutos, David J. Mann, Edward W. Tate

168) Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis (ACS Chemical Biology) Monday June 6th 2016
Kalyan Das, Jan Balzarini, Matthew T. Miller, Anita R. Maguire, Jeffrey J. DeStefano, Eddy Arnold

169) A Novel Destabilizing Domain Based on a Small-Molecule Dependent Fluorophore (ACS Chemical Biology) Monday June 6th 2016
Raul Navarro, Ling-chun Chen, Rishi Rakhit, Thomas J. Wandless

170) Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo (ACS Chemical Biology) Monday June 6th 2016
Thomas B. Sundberg, Yanke Liang, Huixian Wu, Hwan Geun Choi, Nam Doo Kim, Taebo Sim, Liv Johannessen, Adam Petrone, Bernard Khor, Daniel B. Graham, Isabel J. Latorre, Andrew J. Phillips, Stuart L. Schreiber, Jose Perez, Alykhan F. Shamji, Nathanael S. Gray, Ramnik J. Xavier

171) Protein (ACS Chemical Biology) Friday June 3rd 2016
Sabine Milhas, Brigitt Raux, Ste

172) Elucidation of the Teixobactin Pharmacophore (ACS Chemical Biology) Friday June 3rd 2016
Hyunjun Yang, Kevin H. Chen, James S. Nowick

173) Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations (ACS Chemical Biology) Friday June 3rd 2016
Luca Unione, Gabriel Ortega, Alvaro Mallagaray, Francisco Corzana, Javier Pe

174) Nontrivial Effect of the Color-Exchange of a Donor/Acceptor Pair in the Engineering of Fo (ACS Chemical Biology) Wednesday June 1st 2016
Yusaku Ohta, Takanori Kamagata, Asuka Mukai, Shinji Takada, Takeharu Nagai, Kazuki Horikawa

175) Thiol-Activated HNO Release from a Ruthenium Antiangiogenesis Complex and HIF-1 (ACS Chemical Biology) Wednesday June 1st 2016
Eduardo Henrique Silva Sousa, Lisa A. Ridnour, Flore

176) pH-Dependent DNA Distortion and Repression of Gene Expression by Pectobacterium atrosepticum PecS (ACS Chemical Biology) Friday May 27th 2016
Dinesh K. Deochand, Jacob K. Meariman, Anne Grove

177) Advances in Enzymatic Glycoside Synthesis (ACS Chemical Biology) Thursday May 26th 2016
Phillip M. Danby, Stephen G. Withers

178) Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules (ACS Chemical Biology) Thursday May 26th 2016
Mackenzie D. Martin, Jeremy D. Baker, Amirthaa Suntharalingam, Bryce A. Nordhues, Lindsey B. Shelton, Dali Zheng, Jonathan J. Sabbagh, Timothy A.J. Haystead, Jason E. Gestwicki, Chad A. Dickey

179) Perspectives on Anti-Glycan Antibodies Gleaned from Development of a Community Resource Database (ACS Chemical Biology) Wednesday May 25th 2016
Eric Sterner, Natalie Flanagan, Jeffrey C. Gildersleeve

180) Profiling Esterases in Mycobacterium tuberculosis Using Far-Red Fluorogenic Substrates (ACS Chemical Biology) Monday May 23rd 2016
Katie R. Tallman, Samantha R. Levine, Kimberly E. Beatty

181) Conjugation Strategy Strongly Impacts the Conformational Stability of a PEG-Protein Conjugate (ACS Chemical Biology) Saturday May 21st 2016
Paul B. Lawrence, Wendy M. Billings, McKenzie B. Miller, Brijesh K. Pandey, Andrew R. Stephens, Minnie I. Langlois, Joshua L. Price

182) Monitoring Nitric Oxide in Subcellular Compartments by Hybrid Probe Based on Rhodamine Spirolactam and SNAP-tag (ACS Chemical Biology) Friday May 20th 2016
Chao Wang, Xinbo Song, Zhuo Han, Xiaoyu Li, Yongping Xu, Yi Xiao

183) The Hidden Conformation of Lewis x, a Human Histo-Blood Group Antigen, Is a Determinant for Recognition by Pathogen Lectins (ACS Chemical Biology) Friday May 20th 2016
Je

184) Cladribine and Fludarabine Nucleotides Induce Distinct Hexamers Defining a Common Mode of Reversible RNR Inhibition (ACS Chemical Biology) Friday May 20th 2016
Somsinee Wisitpitthaya, Yi Zhao, Marcus J. C. Long, Minxing Li, Elaine A. Fletcher, William A. Blessing, Robert S. Weiss, Yimon Aye

185) Characterization of Three Tailoring Enzymes in Dutomycin Biosynthesis and Generation of a Potent Antibacterial Analogue (ACS Chemical Biology) Thursday May 19th 2016
Lei Sun, Siyuan Wang, Shuwei Zhang, Lei Shao, Qian Zhang, Chad Skidmore, Cheng-Wei Tom Chang, Dayu Yu, Jixun Zhan

186) Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics (ACS Chemical Biology) Thursday May 19th 2016
Ge

187) Structure (ACS Chemical Biology) Wednesday May 18th 2016
Tian Yang, Yftah Tal-Gan, Alexandra E. Paharik, Alexander R. Horswill, Helen E. Blackwell

188) A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes (ACS Chemical Biology) Tuesday May 17th 2016
Wesley Wei Wang, Yu Zeng, Bo Wu, Alexander Deiters, Wenshe R. Liu

189) Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure (ACS Chemical Biology) Tuesday May 17th 2016
Tengfeng Ni, Fei Ye, Xing Liu, Jie Zhang, Hongchuan Liu, Jiahui Li, Yingyi Zhang, Yingqiang Sun, Meining Wang, Cheng Luo, Hualiang Jiang, Lefu Lan, Jianhua Gan, Ao Zhang, Hu Zhou, Cai-Guang Yang

190) Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects (ACS Chemical Biology) Friday May 13th 2016
Florence F. Wagner, Joshua A. Bishop, Jennifer P. Gale, Xi Shi, Michelle Walk, Joshua Ketterman, Debasis Patnaik, Doug Barker, Deepika Walpita, Arthur J. Campbell, Shannon Nguyen, Michael Lewis, Linda Ross, Michel Wei

191) Sequence-Specific Biosensing of DNA Target through Relay PCR with Small-Molecule Fluorophore (ACS Chemical Biology) Thursday May 12th 2016
Afshan Yasmeen, Feng Du, Yongyun Zhao, Juan Dong, Haodong Chen, Xin Huang, Xin Cui, Zhuo Tang

192) Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector (ACS Chemical Biology) Thursday May 12th 2016
Willy Jablonka, Van Pham, Glenn Nardone, Apostolos Gittis, Li

193) Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK (ACS Chemical Biology) Wednesday May 11th 2016
Danielle L. Schmitt, Yun-ju Cheng, Junyong Park, Songon An

194) Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening (ACS Chemical Biology) Wednesday May 11th 2016
Peter Man-Un Ung, Wenxin Song, Lili Cheng, Xinbin Zhao, Hailin Hu, Ligong Chen, Avner Schlessinger

195) Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2 (ACS Chemical Biology) Wednesday May 11th 2016
Christophe Marchand, Monica Abdelmalak, Jayakanth Kankanala, Shar-Yin Huang, Evgeny Kiselev, Katherine Fesen, Kayo Kurahashi, Hiroyuki Sasanuma, Shunichi Takeda, Hideki Aihara, Zhengqiang Wang, Yves Pommier

196) Discovery of a novel NEDD8 Activating Enzyme Inhibitor with Piperidin-4-amine Scaffold by Structure-Based Virtual Screening (ACS Chemical Biology) Friday May 6th 2016
Peng Lu, Xiaoxin Liu, Xinrui Yuan, Minfang He, Yubin Wang, Qi Zhang, Ping-kai Ouyang

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