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99) Biophysical and Biological Characterization of Hairpin and Molecular Beacon RNase H Active Antisense Oligonucleotides (ACS Chemical Biology) Friday February 13th 2015
Michael E.

100) Insights into Methyltransferase Specificity and Bioactivity of Derivatives of the Antibiotic Plantazolicin (ACS Chemical Biology) Wednesday February 11th 2015
Yue Hao, Patricia M. Blair, Abhishek Sharma, Douglas A. Mitchell, Satish K. Nair

101) Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines (ACS Chemical Biology) Monday February 9th 2015
Da Duan, Allison K. Doak, Lyudmila Nedyalkova, Brian K. Shoichet

102) Visualizing Cell Proximity with Genetically Encoded Bioluminescent Reporters (ACS Chemical Biology) Monday February 9th 2015
Krysten A. Jones, David J. Li, Elliot Hui, Mark A. Sellmyer, Jennifer A. Prescher

103) Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain (ACS Chemical Biology) Thursday February 5th 2015
E. Railey White, Luxin Sun, Zhong Ma, Jason M. Beckta, Brittany A. Danzig, David E. Hacker, Melissa Huie, David C. Williams, Ross A. Edwards, Kristoffer Valerie, J. N. Mark Glover, Matthew C. T. Hartman

104) Synergistic Binding of the Leader and Core Peptides by the Lantibiotic Synthetase HalM2 (ACS Chemical Biology) Wednesday February 4th 2015
Gabrielle N. Thibodeaux, Amanda L. McClerren, Yunli Ma, Marc R. Gancayco, Wilfred A. van der Donk

105) Identification of Potent Phosphodiesterase Inhibitors that Demonstrate Cyclic Nucleotide-Dependent Functions in Apicomplexan Parasites (ACS Chemical Biology) Wednesday February 4th 2015
Brittany L. Howard, Katherine L. Harvey, Rebecca J. Stewart, Mauro F. Azevedo, Brendan S. Crabb, Ian G. Jennings, Paul R. Sanders, David T. Manallack, Philip E. Thompson, Christopher J. Tonkin, Paul R. Gilson

106) Isofunctional Enzymes PAD1 and UbiX Catalyze Formation of a Novel Cofactor Required by Ferulic Acid Decarboxylase and 4-Hydroxy-3-polyprenylbenzoic Acid Decarboxylase (ACS Chemical Biology) Tuesday February 3rd 2015
Fengming Lin, Kyle L. Ferguson, David R. Boyer, Xiaoxia Nina Lin, E. Neil G. Marsh

107) Structural Basis of New Allosteric Inhibition in Kinesin Spindle Protein Eg5 (ACS Chemical Biology) Tuesday February 3rd 2015
Hideshi Yokoyama, Jun-ichi Sawada, Shiori Katoh, Kenji Matsuno, Naohisa Ogo, Yoshinobu Ishikawa, Hiroshi Hashimoto, Satoshi Fujii, Akira Asai

108) Structural Basis of a Temporin 1b Analogue Antimicrobial Activity against Gram Negative Bacteria Determined by CD and NMR Techniques in Cellular Environment (ACS Chemical Biology) Friday January 30th 2015
Gaetano Malgieri, Concetta Avitabile, Maddalena Palmieri, Luca Domenico D

109) Structure-Guided Design of a High Affinity Inhibitor to Human CtBP (ACS Chemical Biology) Friday January 30th 2015
Brendan J. Hilbert, Benjamin L. Morris, Keith C. Ellis, Janet L. Paulsen, Celia A. Schiffer, Steven R. Grossman, William E. Royer

110) Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites (ACS Chemical Biology) Friday January 30th 2015
I. J. Frame, Roman Deniskin, Alison Rinderspacher, Francine Katz, Shi-Xian Deng, Robyn D. Moir, Sophie H. Adjalley, Olivia Coburn-Flynn, David A. Fidock, Ian M. Willis, Donald W. Landry, Myles H. Akabas

111) Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes That Promote Autophagic Tau Clearance (ACS Chemical Biology) Friday January 30th 2015
Mackenzie D. Martin, Laurent Calcul, Courtney Smith, Umesh K. Jinwal, Sarah N. Fontaine, April Darling, Kent Seeley, Lukasz Wojtas, Malathi Narayan, Jason E. Gestwicki, Garry R. Smith, Allen B. Reitz, Bill J. Baker, Chad A. Dickey

112) Genetically Enhanced Lysozyme Evades a Pathogen Derived Inhibitory Protein (ACS Chemical Biology) Friday January 30th 2015
Sarah M. Dostal, Yongliang Fang, Jonathan C. Guerrette, Thomas C. Scanlon, Karl E. Griswold

113) Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes (ACS Chemical Biology) Thursday January 29th 2015
Erik C. Hett, Hua Xu, Kieran F. Geoghegan, Ariamala Gopalsamy, Robert E. Kyne, Carol A. Menard, Arjun Narayanan, Mihir D. Parikh, Shenping Liu, Lee Roberts, Ralph P. Robinson, Michael A. Tones, Lyn H. Jones

114) C5-Epimerase and 2-O-Sulfotransferase Associate in Vitro to Generate Contiguous Epimerized and 2-O-Sulfated Heparan Sulfate Domains (ACS Chemical Biology) Wednesday January 28th 2015
Aure

115) Computational Design and Experimental Characterization of Peptides Intended for pH-Dependent Membrane Insertion and Pore Formation (ACS Chemical Biology) Wednesday January 28th 2015
Yao Zhang, Rene

116) Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1 (ACS Chemical Biology) Wednesday January 28th 2015
Michael T. Perfetti, Brandi M. Baughman, Bradley M. Dickson, Yunxiang Mu, Gaofeng Cui, Pavel Mader, Aiping Dong, Jacqueline L. Norris, Scott B. Rothbart, Brian D. Strahl, Peter J. Brown, William P. Janzen, Cheryl H. Arrowsmith, Georges Mer, Kevin M. McBride, Lindsey I. James, Stephen V. Frye

117) Genetic Targeting of a Small Fluorescent Zinc Indicator to Cell Surface for Monitoring Zinc Secretion (ACS Chemical Biology) Tuesday January 27th 2015
Daliang Li, Lin Liu, Wen-Hong Li

118) Small Molecule Inhibitors of Disulfide Bond Formation by the Bacterial DsbA (ACS Chemical Biology) Tuesday January 27th 2015
Maria A. Halili, Prabhakar Bachu, Fredrik Lindahl, Che

119) Stereospecific Phosphorylation by the Central Mitotic Kinase Cdk1-Cyclin B (ACS Chemical Biology) Monday January 26th 2015
Felicia A. Etzkorn, Song Zhao

120) Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design (ACS Chemical Biology) Monday January 26th 2015
Daniel J. Slade, Pengfei Fang, Christina J. Dreyton, Ying Zhang, Jakob Furhmann, Don Rempel, Benjamin D. Bax, Scott A. Coonrod, Huw D. Lewis, Min Guo, Michael L. Gross, Paul R. Thompson

121) Family of Class I Lantibiotics from Actinomycetes and Improvement of Their Antibacterial Activities (ACS Chemical Biology) Friday January 23rd 2015
Sonia I. Maffioli, Paolo Monciardini, Bruno Catacchio, Carlo Mazzetti, Daniela Mu

122) The Elastase-PK101 Structure: Mechanism of an Ultrasensitive Activity-based Probe Revealed (ACS Chemical Biology) Thursday January 22nd 2015
Bernhard C. Lechtenberg, Paulina Kasperkiewicz, Howard Robinson, Marcin Drag, Stefan J. Riedl

123) Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water (ACS Chemical Biology) Thursday January 22nd 2015
Fumito Saito, Hidetoshi Noda, Jeffrey W. Bode

124) Structural and Functional Analysis of the Loading Acyltransferase from Avermectin Modular Polyketide Synthase (ACS Chemical Biology) Thursday January 22nd 2015
Fen Wang, Yanjie Wang, Junjie Ji, Zhan Zhou, Jingkai Yu, Hua Zhu, Zhiguo Su, Lixin Zhang, Jianting Zheng

125) Chemical Cross-Linking/Mass Spectrometry Maps the Amyloid (ACS Chemical Biology) Wednesday January 21st 2015
Ste

126) Modulation of Alternative Splicing with Chemical Compounds in New Therapeutics for Human Diseases (ACS Chemical Biology) Tuesday January 20th 2015
Kenji Ohe, Masatoshi Hagiwara

127) Saturation Mutagenesis of TsrA Ala4 Unveils a Highly Mutable Residue of Thiostrepton A (ACS Chemical Biology) Tuesday January 20th 2015
Feifei Zhang, Wendy L. Kelly

128) Genetically Encoding Lysine Modifications on Histone H4 (ACS Chemical Biology) Tuesday January 20th 2015
Bryan J. Wilkins, Liljan E. Hahn, Svenja Heitmu

129) Ironing out Their Differences: Dissecting the Structural Determinants of a Phenylalanine Aminomutase and Ammonia Lyase (ACS Chemical Biology) Tuesday January 20th 2015
Matthew M. Heberling, Marcelo F. Masman, Sebastian Bartsch, Gjalt G. Wybenga, Bauke W. Dijkstra, Siewert J. Marrink, Dick B. Janssen

130) Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival (ACS Chemical Biology) Tuesday January 20th 2015
Jae Won Chang, Andrea M. Zuhl, Anna E. Speers, Sherry Niessen, Steven J. Brown, Melinda M. Mulvihill, Yi Chiao Fan, Timothy P. Spicer, Mark Southern, Louis Scampavia, Virneliz Fernandez-Vega, Melissa M. Dix, Michael D. Cameron, Peter S. Hodder, Hugh Rosen, Daniel K. Nomura, Ohyun Kwon, Ku-Lung Hsu, Benjamin F. Cravatt

131) Manganese and Microbial Pathogenesis: Sequestration by the Mammalian Immune System and Utilization by Microorganisms (ACS Chemical Biology) Friday January 16th 2015
Megan Brunjes Brophy, Elizabeth M. Nolan

132) Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling (ACS Chemical Biology) Thursday January 15th 2015
Lu Wei, Yihui Shen, Fang Xu, Fanghao Hu, Jamie K. Harrington, Kimara L. Targoff, Wei Min

133) Solution Structure, Aggregation Behavior, and Flexibility of Human Relaxin-2 (ACS Chemical Biology) Thursday January 15th 2015
Linda M. Haugaard-Kedstro

134) Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement (ACS Chemical Biology) Thursday January 15th 2015
Joanna S. Yi, Alexander J. Federation, Jun Qi, Sirano Dhe-Paganon, Michael Hadler, Xiang Xu, Roodolph St. Pierre, Anthony C. Varca, Lei Wu, Jason J. Marineau, William B. Smith, Amanda Souza, Emma J. Chory, Scott A. Armstrong, James E. Bradner

135) Structural Basis for Regulation of RNA-Binding Proteins by Phosphorylation (ACS Chemical Biology) Wednesday January 14th 2015
Roopa Thapar

136) Determination of the Formylglycinamide Ribonucleotide Amidotransferase Ammonia Pathway by Combining 3D-RISM Theory with Experiment (ACS Chemical Biology) Wednesday January 14th 2015
Ajay S. Tanwar, Daniel J. Sindhikara, Fumio Hirata, Ruchi Anand

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137) HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of (ACS Chemical Biology) Thursday January 8th 2015
Jonathan Iaconelli, Joanne H. Huang, Shaunna S. Berkovitch, Shrikanta Chattopadhyay, Ralph Mazitschek, Stuart L. Schreiber, Stephen J. Haggarty, Rakesh Karmacharya

138) Inactivation of Multiple Bacterial Histidine Kinases by Targeting the ATP-Binding Domain (ACS Chemical Biology) Thursday January 8th 2015
Kaelyn E. Wilke, Samson Francis, Erin E. Carlson

139) An Alternate Pathway of Arsenate Resistance in E. coli Mediated by the Glutathione S-Transferase GstB (ACS Chemical Biology) Wednesday January 7th 2015
Constantine Chrysostomou, Erik M. Quandt, Nicholas M. Marshall, Everett Stone, George Georgiou

140) Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors (ACS Chemical Biology) Tuesday January 6th 2015
Michael B. Lazarus, Chris J. Novotny, Kevan M. Shokat

141) Quantitative Imaging of Glutathione in Live Cells Using a Reversible Reaction-Based Ratiometric Fluorescent Probe (ACS Chemical Biology) Tuesday January 6th 2015
Xiqian Jiang, Yong Yu, Jianwei Chen, Mingkun Zhao, Hui Chen, Xianzhou Song, Alexander J. Matzuk, Shaina L. Carroll, Xiao Tan, Antons Sizovs, Ninghui Cheng, Meng C. Wang, Jin Wang

142) Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1 (ACS Chemical Biology) Tuesday January 6th 2015
Min Luo, Kent S. Gates, Michael T. Henzl, John J. Tanner

143) Consequences of Periodic (ACS Chemical Biology) Monday January 5th 2015
Ross W. Cheloha, Jeremy A. Sullivan, Tong Wang, Jordan M. Sand, John Sidney, Alessandro Sette, Mark E. Cook, M. Suresh, Samuel H. Gellman

144) Interactions of the Natural Product (+)-Avrainvillamide with Nucleophosmin and Exportin-1 Mediate the Cellular Localization of Nucleophosmin and its AML-Associated Mutants (ACS Chemical Biology) Monday January 5th 2015
Herschel Mukherjee, Kok-Ping Chan, Vibeke Andresen, Mariah L. Hanley, Bj

145) Unexpected Off-Targets and Paradoxical Pathway Activation by Kinase Inhibitors (ACS Chemical Biology) Friday January 2nd 2015
Oliver Hantschel

146) Computational Design of a Time-Dependent Histone Deacetylase 2 Selective Inhibitor (ACS Chemical Biology) Friday January 2nd 2015
Jingwei Zhou, Min Li, Nanhao Chen, Shenglong Wang, Hai-Bin Luo, Yingkai Zhang, Ruibo Wu

147) Effective GTP-Replacing FtsZ Inhibitors and Antibacterial Mechanism of Action (ACS Chemical Biology) Wednesday December 31st 2014
Marta Artola, Laura B. Ruiz-Avila, Albert Vergon

148) Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals (ACS Chemical Biology) Wednesday December 31st 2014
Thillai V. Sekar, Kira Foygel, Rammohan Devulapally, Ramasamy Paulmurugan

149) Topology Specific Stabilization of Promoter over Telomeric G-Quadruplex DNAs by Bisbenzimidazole Carboxamide Derivatives (ACS Chemical Biology) Friday December 26th 2014
V. Dhamodharan, S. Harikrishna, Achikanath C. Bhasikuttan, P. I. Pradeepkumar

150) Bacterial Histidine Kinases as Novel Antibacterial Drug Targets (ACS Chemical Biology) Friday December 26th 2014
Agnieszka E. Bem, Nadya Velikova, M. Teresa Pellicer, Peter van Baarlen, Alberto Marina, Jerry M. Wells

151) Classification of Chemical Chaperones Based on Their Effect on Protein Folding Landscapes (ACS Chemical Biology) Wednesday December 24th 2014
Rohan Dandage, Anannya Bandyopadhyay, Gopal Gunanathan Jayaraj, Kanika Saxena, Vijit Dalal, Aritri Das, Kausik Chakraborty

152) Small Molecule Substrate Phosphorylation Site Inhibitors of Protein Kinases: Approaches and Challenges (ACS Chemical Biology) Tuesday December 23rd 2014
Meghan E. Breen, Matthew B. Soellner

153) Demonstration of a Folding after Binding Mechanism in the Recognition between the Measles Virus NTAIL and X Domains (ACS Chemical Biology) Monday December 22nd 2014
Marion Dosnon, Daniela Bonetti, Angela Morrone, Jenny Erales, Eva di Silvio, Sonia Longhi, Stefano Gianni

154) Structure-Based Design of a B Cell Antigen from B. pseudomallei (ACS Chemical Biology) Monday December 22nd 2014
Davide Gaudesi, Claudio Peri, Giacomo Quilici, Alessandro Gori, Mario Ferrer-Navarro, Oscar Conchillo-Sole

155) Targeting Conformational Plasticity of Protein Kinases (ACS Chemical Biology) Friday December 19th 2014
Michael Tong, Markus A. Seeliger

156) Gliotoxin Suppresses NF- (ACS Chemical Biology) Wednesday December 17th 2014
Hiroki Sakamoto, Shinichiro Egashira, Nae Saito, Takayoshi Kirisako, Simon Miller, Yoshiteru Sasaki, Tadahiko Matsumoto, Manabu Shimonishi, Toru Komatsu, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Hirotatsu Kojima, Takayoshi Okabe, Soichi Wakatsuki, Kazuhiro Iwai, Tetsuo Nagano

157) Discovery of Native Autoantigens via Antigen Surrogate Technology: Application to Type 1 Diabetes (ACS Chemical Biology) Wednesday December 17th 2014
Todd M. Doran, Scott Simanski, Thomas Kodadek

158) Quantitative Proteomics of Kinase Inhibitor Targets and Mechanisms (ACS Chemical Biology) Wednesday December 17th 2014
Henrik Daub

159) Molecular Perspectives on Protein Adenylylation (ACS Chemical Biology) Wednesday December 17th 2014
Christian Hedberg, Aymelt Itzen

160) Quasithermodynamic Contributions to the Fluctuations of a Protein Nanopore (ACS Chemical Biology) Monday December 15th 2014
Belete R. Cheneke, Bert van den Berg, Liviu Movileanu

161) Functional Manipulation of Dendritic Cells by Photoswitchable Generation of Intracellular Reactive Oxygen Species (ACS Chemical Biology) Friday December 12th 2014
Taek-Chin Cheong, Eon Pil Shin, Eun-Kyung Kwon, Ji-Hye Choi, Kang-Kyun Wang, Prashant Sharma, Kyong Hoon Choi, Jin-Muk Lim, Hong-Gee Kim, Keunhee Oh, Ju-Hong Jeon, Insuk So, In-Gyu Kim, Myung-Sik Choi, Young Keun Kim, Seung-Yong Seong, Yong-Rok Kim, Nam-Hyuk Cho

162) Allele-Specific Chemical Genetics: Concept, Strategies, and Applications (ACS Chemical Biology) Friday December 12th 2014
Kabirul Islam

163) Binding of Human Proteins to Amyloid- (ACS Chemical Biology) Friday December 12th 2014
M. Mahafuzur Rahman, Henrik Zetterberg, Christofer Lendel, Torleif Ha

164) Single Asparagine to Arginine Mutation Allows PerR to Switch from PerR Box to Fur Box (ACS Chemical Biology) Thursday December 11th 2014
Christelle Caux-Thang, Aube

165) Detection of Tumor-Associated Glycopeptides by Lectins: The Peptide Context Modulates Carbohydrate Recognition (ACS Chemical Biology) Wednesday December 10th 2014
David Madariaga, Nuria Marti

166) 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 (ACS Chemical Biology) Wednesday December 10th 2014
Joa

167) DFGmodel: Predicting Protein Kinase Structures in Inactive States for Structure-Based Discovery of Type-II Inhibitors (ACS Chemical Biology) Wednesday December 10th 2014
Peter Man-Un Ung, Avner Schlessinger

168) Protein Prenylation: Enzymes, Therapeutics, and Biotechnology Applications (ACS Chemical Biology) Monday December 8th 2014
Charuta C. Palsuledesai, Mark D. Distefano

169) Acetylation of Trehalose Mycolates Is Required for Efficient MmpL-Mediated Membrane Transport in Corynebacterineae (ACS Chemical Biology) Monday December 8th 2014
Yoshiki Yamaryo-Botte, Arek K. Rainczuk, David J. Lea-Smith, Rajini Brammananth, Phillip L. van der Peet, Peter Meikle, Julie E. Ralton, Thusita W. T. Rupasinghe, Spencer J. Williams, Ross L. Coppel, Paul K. Crellin, Malcolm J. McConville

170) Directed Evolution of New and Improved Enzyme Functions Using an Evolutionary Intermediate and Multidirectional Search (ACS Chemical Biology) Saturday December 6th 2014
Joanne L. Porter, Priscilla L. S. Boon, Tracy P. Murray, Thomas Huber, Charles A. Collyer, David L. Ollis

171) Pseudoaeruginosins, Nonribosomal Peptides in Nodularia spumigena (ACS Chemical Biology) Friday December 5th 2014
Liwei Liu, Adnan Budnjo, Jouni Jokela, Bengt Erik Haug, David P. Fewer, Matti Wahlsten, Leo Rouhiainen, Perttu Permi, Torgils Fossen, Kaarina Sivonen

172) Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis (ACS Chemical Biology) Friday December 5th 2014
Nan Zhao, Crystal M. Darby, Jennifer Small, Daniel A. Bachovchin, Xiuju Jiang, Kristin E. Burns-Huang, Helene Botella, Sabine Ehrt, Dale L. Boger, Erin D. Anderson, Benjamin F. Cravatt, Anna E. Speers, Virneliz Fernandez-Vega, Peter S. Hodder, Christina Eberhart, Hugh Rosen, Timothy P. Spicer, Carl F. Nathan

173) Interfacing Chemical Biology and Drug Discovery: Report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2 (ACS Chemical Biology) Friday December 5th 2014
Janos Sapi, Fre

174) Identifying Modulators of CXC Receptors 3 and 4 with Tailored Selectivity Using Multi-Target Docking (ACS Chemical Biology) Friday December 5th 2014
Denis Schmidt, Viachaslau Bernat, Regine Brox, Nuska Tschammer, Peter Kolb

175) Probing Interactions between Lysine Residues in Histone Tails and Nucleosomal DNA via Product and Kinetic Analysis (ACS Chemical Biology) Friday December 5th 2014
Liwei Weng, Chuanzheng Zhou, Marc M. Greenberg

176) Natural Combinatorial Biosynthesis Involving Two Clusters for the Synthesis of Three Pyrrolamides in Streptomyces netropsis (ACS Chemical Biology) Thursday December 4th 2014
Audrey Vingadassalon, Florence Lorieux, Maud Juguet, Ge

177) Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48 (ACS Chemical Biology) Thursday December 4th 2014
Sushmita D. Lahiri, Stefano Mangani, Haris Jahic

178) Hsp90 C-Terminal Inhibitors Exhibit Antimigratory Activity by Disrupting the Hsp90 (ACS Chemical Biology) Wednesday December 3rd 2014
Suman Ghosh, Heather E. Shinogle, Gaurav Garg, George A. Vielhauer, Jeffrey M. Holzbeierlein, Rick T. Dobrowsky, Brian S. J. Blagg

179) Inhibition of CDC25B Phosphatase Through Disruption of Protein (ACS Chemical Biology) Monday December 1st 2014
George Lund, Sergii Dudkin, Dmitry Borkin, Wendi Ni, Jolanta Grembecka, Tomasz Cierpicki

180) Anticancer/Antiviral Agent Akt Inhibitor-IV Massively Accumulates in Mitochondria and Potently Disrupts Cellular Bioenergetics (ACS Chemical Biology) Monday December 1st 2014
J. Matthew Meinig, Blake R. Peterson

181) Synthesis and Biological Evaluation of Optimized Inhibitors of the Mitotic Kinesin Kif18A (ACS Chemical Biology) Wednesday November 26th 2014
Joachim Braun, Martin M. Mo

182) Cardiac Glycoside Activities Link Na+/K+ ATPase Ion-Transport to Breast Cancer Cell Migration via Correlative SAR (ACS Chemical Biology) Wednesday November 26th 2014
Anniefer N. Magpusao, George Omolloh, Joshua Johnson, Jose

183) Chemical Probes of Histone Lysine Methyltransferases (ACS Chemical Biology) Tuesday November 25th 2014
H. U

184) An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins (ACS Chemical Biology) Tuesday November 25th 2014
Carrie J. Marshall, Vanessa A. Grosskopf, Taylor J. Moehling, Benjamin J. Tillotson, Gregory J. Wiepz, Nicholas L. Abbott, Ronald T. Raines, Eric V. Shusta

185) Sequence-Specific Generation of 1,N6-Ethenoadenine and 3,N4-Ethenocytosine in Single-Stranded Unmodified DNA (ACS Chemical Biology) Tuesday November 25th 2014
David Egloff, Igor A. Oleinich, Eva Freisinger

186) Fluorogen-Activating Proteins Provide Tunable Labeling Densities for Tracking Fc (ACS Chemical Biology) Tuesday November 25th 2014
Samantha L. Schwartz, Qi Yan, Cheryl A. Telmer, Keith A. Lidke, Marcel P. Bruchez, Diane S. Lidke

187) Understanding Dengue Virus Capsid Protein Disordered N-Terminus and pep14-23-Based Inhibition (ACS Chemical Biology) Thursday November 20th 2014
Andre

188) Drugging Sphingosine Kinases (ACS Chemical Biology) Wednesday November 19th 2014
Webster L. Santos, Kevin R. Lynch

189) Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes (ACS Chemical Biology) Wednesday November 19th 2014
Sarah A. Scott, Cierra T. Spencer, Matthew C. O

190) Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate (ACS Chemical Biology) Tuesday November 18th 2014
Jing Fan, Xin Teng, Ling Liu, Katherine R. Mattaini, Ryan E. Looper, Matthew G. Vander Heiden, Joshua D. Rabinowitz

191) Structural Details of Light Activation of the LOV2-based Photoswitch PA-Rac1 (ACS Chemical Biology) Monday November 17th 2014
Andreas Winkler, Thomas R. M. Barends, Aniko

192) Revealing Structural Changes of Prion Protein during Conversion from (ACS Chemical Biology) Friday November 14th 2014
Che Yang, Wei-Lin Lo, Yun-Hsuan Kuo, Jason C. Sang, Chung-Yu Lee, Yun-Wei Chiang, Rita P.-Y. Chen

193) Sulfhydryl-Specific Probe for Monitoring Protein Redox Sensitivity (ACS Chemical Biology) Friday November 14th 2014
Jae-Jin Lee, Sura Ha, Hee-Jung Kim, Hyun Joo Ha, Hee-Yoon Lee, Kong-Joo Lee

194) Polymer-Based Synthetic Dendritic Cells for Tailoring Robust and Multifunctional T Cell Responses (ACS Chemical Biology) Thursday November 13th 2014
Subhra Mandal, Roel Hammink, Jurjen Tel, Zaskia H. Eksteen-Akeroyd, Alan E. Rowan, Kerstin Blank, Carl G. Figdor

195) Subtype-Specific Modulation of Estrogen Receptor (ACS Chemical Biology) Tuesday November 11th 2014
Inga M. Tharun, Lidia Nieto, Christian Haase, Marcel Scheepstra, Mark Balk, Sabine Mo

196) Time-Resolved FRET Binding Assay to Investigate Hetero-Oligomer Binding Properties: Proof of Concept with Dopamine D1/D3 Heterodimer (ACS Chemical Biology) Tuesday November 11th 2014
Candide Hounsou, Jean-Franc

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