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1) Synthetic Proteins Potently and Selectively Bind the Oncoprotein Gankyrin, Modulate Its Interaction with S6 ATPase, and Suppress Gankyrin/MDM2-Dependent Ubiquitination of p53 (ACS Chemical Biology) Friday May 22nd 2015
Alex M. Chapman, Brian R. McNaughton

2) Simultaneously Targeting the NS3 Protease and Helicase Activities for More Effective Hepatitis C Virus Therapy (ACS Chemical Biology) Friday May 22nd 2015
Jean Ndjomou, M. Josie Corby, Noreena L. Sweeney, Alicia M. Hanson, Cihan Aydin, Akbar Ali, Celia A. Schiffer, Kelin Li, Kevin J. Frankowski, Frank J. Schoenen, David N. Frick

3) Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes (ACS Chemical Biology) Friday May 22nd 2015
Satyamaheshwar Peddibhotla, Pauline Fontaine, Chi K. Leung, Patrick Maloney, Paul M. Hershberger, Ying Wang, Michelle S. Bousquet, Hendrik Luesch, Arianna Mangravita-Novo, Anthony B. Pinkerton, Layton H. Smith, Siobhan Malany, Keith Choe

4) A Synthetic Factor XIIa Inhibitor Blocks Selectively Intrinsic Coagulation Initiation (ACS Chemical Biology) Tuesday May 19th 2015
Vanessa Baeriswyl, Sara Calzavarini, Shiyu Chen, Alessandro Zorzi, Luca Bologna, Anne Angelillo-Scherrer, Christian Heinis

5) A Disulfide Stabilized (ACS Chemical Biology) Monday May 18th 2015
Aswani K. Kancherla, Srinu Meesala, Pooja Jorwal, Ramasamy Palanisamy, Sujit K. Sikdar, Siddhartha P. Sarma

6) Ribosomal Synthesis of Macrocyclic Peptides in Vitro and in Vivo Mediated by Genetically Encoded Aminothiol Unnatural Amino Acids (ACS Chemical Biology) Friday May 15th 2015
John R. Frost, Nicholas T. Jacob, Louis J. Papa, Andrew E. Owens, Rudi Fasan

7) Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death (ACS Chemical Biology) Friday May 15th 2015
Scott J. Dixon, Georg E. Winter, Leila S. Musavi, Eric D. Lee, Berend Snijder, Manuele Rebsamen, Giulio Superti-Furga, Brent R. Stockwell

8) A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2 (ACS Chemical Biology) Friday May 15th 2015
Barbara Guerra, Nils Bischoff, Volodymyr G. Bdzhola, Sergiy M. Yarmoluk, Olaf-Georg Issinger, Andriy G. Golub, Karsten Niefind

9) Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein (ACS Chemical Biology) Friday May 15th 2015
Johanna Kastl, Joachim Braun, Andreas Prestel, Heiko M. Mo

10) A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member (ACS Chemical Biology) Friday May 15th 2015
Shiho Nakaoka, Kazuki Sasaki, Akihiro Ito, Yoichi Nakao, Minoru Yoshida

11) Incorporation of Unnatural Amino Acids in Response to the AGG Codon (ACS Chemical Biology) Tuesday May 12th 2015
Byeong Sung Lee, Seunggun Shin, Jong Yeob Jeon, Kyoung-Soon Jang, Bun Yeol Lee, Sangdun Choi, Tae Hyeon Yoo

12) Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer (ACS Chemical Biology) Thursday May 7th 2015
Rebecca A. Kohnz, Melinda M. Mulvihill, Jae Won Chang, Ku-Lung Hsu, Antonio Sorrentino, Benjamin F. Cravatt, Sourav Bandyopadhyay, Andrei Goga, Daniel K. Nomura

13) Light-Activated Proteolysis for the Spatiotemporal Control of Proteins (ACS Chemical Biology) Thursday May 7th 2015
Quentin Delacour, Chenge Li, Marie-Aude Plamont, Emmanuelle Billon-Denis, Isabelle Aujard, Thomas Le Saux, Ludovic Jullien, Arnaud Gautier

14) Residue-Based Preorganization of BH3-Derived (ACS Chemical Biology) Thursday May 7th 2015
Kimberly J. Peterson-Kaufman, Holly S. Haase, Melissa D. Boersma, Erinna F. Lee, W. Douglas Fairlie, Samuel H. Gellman

15) Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation (ACS Chemical Biology) Wednesday May 6th 2015
Alberto Nilo, Laura Morelli, Irene Passalacqua, Barbara Brogioni, Martin Allan, Filippo Carboni, Alfredo Pezzicoli, Francesca Zerbini, Domenico Maione, Monica Fabbrini, Maria Rosaria Romano, Qi-Ying Hu, Immaculada Margarit, Francesco Berti, Roberto Adamo

16) The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition (ACS Chemical Biology) Wednesday May 6th 2015
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17) Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase (ACS Chemical Biology) Monday May 4th 2015
Kathleen A. Rising, Charisse M. Crenshaw, Hyun Jo Koo, Thangaiah Subramanian, Kareem A. H. Chehade, Courtney Starks, Keith D. Allen, Douglas A. Andres, H. Peter Spielmann, Joseph P. Noel, Joe Chappell

18) Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting (ACS Chemical Biology) Friday May 1st 2015
Curtis D. Hodge, Ross A. Edwards, Craig J. Markin, Darin McDonald, Mary Pulvino, Michael S. Y. Huen, Jiyong Zhao, Leo Spyracopoulos, Michael J. Hendzel, J. N. Mark Glover

19) Deciphering Epigenetic Cytosine Modifications by Direct Molecular Recognition (ACS Chemical Biology) Friday May 1st 2015
Grzegorz Kubik, Daniel Summerer

20) DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization (ACS Chemical Biology) Wednesday April 29th 2015
Miroslav Brecik, Ivana Centa

21) Genetic Incorporation of (ACS Chemical Biology) Wednesday April 29th 2015
Han Xiao, Weimin Xuan, Sida Shao, Tao Liu, Peter G. Schultz

22) Second Generation TQ-Ligation for Cell Organelle Imaging (ACS Chemical Biology) Tuesday April 28th 2015
Xiaoyun Zhang, Ting Dong, Qiang Li, Xiaohui Liu, Lin Li, She Chen, Xiaoguang Lei

23) Gram (ACS Chemical Biology) Monday April 27th 2015
Michael J. Wilhelm, Joel B. Sheffield, Mohammad Sharifian Gh., Yajing Wu, Christian Spahr, Grazia Gonella, Bolei Xu, Hai-Lung Dai

24) Genetic Manipulation of the Pneumocandin Biosynthetic Pathway for Generation of Analogues and Evaluation of Their Antifungal Activity (ACS Chemical Biology) Thursday April 23rd 2015
Yan Li, Li Chen, Qun Yue, Xingzhong Liu, Zhiqiang An, Gerald F. Bills

25) Rutaecarpine Analogues Reduce Lipid Accumulation in Adipocytes via Inhibiting Adipogenesis/Lipogenesis with AMPK Activation and UPR Suppression (ACS Chemical Biology) Thursday April 23rd 2015
Ying-Chun Chen, Xiao-Yi Zeng, Yan He, Hong Liu, Bin Wang, Han Zhou, Jian-Wen Chen, Pei-Qing Liu, Lian-Quan Gu, Ji-Ming Ye, Zhi-Shu Huang

26) Membrane Curvature Affects the Formation of (ACS Chemical Biology) Wednesday April 22nd 2015
Satoshi Fujii, Tomoaki Matsuura, Tetsuya Yomo

27) Covalent Molecular Probes for Class A G Protein-Coupled Receptors: Advances and Applications (ACS Chemical Biology) Wednesday April 22nd 2015
Dietmar Weichert, Peter Gmeiner

28) Substrate-Controlled Stereochemistry in Natural Product Biosynthesis (ACS Chemical Biology) Monday April 20th 2015
Wei Ding, Yongzhen Li, Qi Zhang

29) A Genetically Encoded FRET Sensor for Intracellular Heme (ACS Chemical Biology) Friday April 17th 2015
Yanqun Song, Maiyun Yang, Seraphine V. Wegner, Jingyi Zhao, Rongfeng Zhu, Yun Wu, Chuan He, Peng R. Chen

30) Diacylglycerol Metabolism and Signaling Is a Driving Force Underlying FASN Inhibitor Sensitivity in Cancer Cells (ACS Chemical Biology) Friday April 17th 2015
Daniel I. Benjamin, Daniel S. Li, Wallace Lowe, Timothy Heuer, George Kemble, Daniel K. Nomura

31) Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism (ACS Chemical Biology) Thursday April 16th 2015
Dahabada H. J. Lopes, Aida Attar, Gayatri Nair, Eric Hayden, Zhenming Du, Kirsten McDaniel, Som Dutt, Kenny Bravo-Rodriguez, Sumit Mittal, Frank-Gerrit Kla

32) Distinct Metal Isoforms Underlie Promiscuous Activity Profiles of Metalloenzymes (ACS Chemical Biology) Thursday April 16th 2015
Florian Baier, John Chen, Matthew Solomonson, Natalie C.J. Strynadka, Nobuhiko Tokuriki

33) Orthogonal Thiol Functionalization at a Single Atomic Center for Profiling Transthiolation Activity of E1 Activating Enzymes (ACS Chemical Biology) Wednesday April 15th 2015
Mathew Stanley, Cong Han, Axel Knebel, Paul Murphy, Natalia Shpiro, Satpal Virdee

34) A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation (ACS Chemical Biology) Wednesday April 15th 2015
Alison Ribeiro, Silvia Pontis, Luisa Mengatto, Andrea Armirotti, Valerio Chiurchiu

35) A Nonapoptotic Role for BAX and BAK in Eicosanoid Metabolism (ACS Chemical Biology) Monday April 6th 2015
Tejia Zhang, Loren D. Walensky, Alan Saghatelian

36) Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation (ACS Chemical Biology) Friday April 3rd 2015
Jessica C. Albright, Matthew T. Henke, Alexandra A. Soukup, Ryan A. McClure, Regan J. Thomson, Nancy P. Keller, Neil L. Kelleher

37) A Simple Method for GFP- and RFP-based Dual Color Single-Molecule Localization Microscopy (ACS Chemical Biology) Wednesday April 1st 2015
Evgenia Platonova, Christian M. Winterflood, Helge Ewers

38) Exquisitely Specific Bisubstrate Inhibitors of c-Src Kinase (ACS Chemical Biology) Tuesday March 31st 2015
Kristoffer R. Brandvold, Shana M. Santos, Meghan E. Breen, Eric J. Lachacz, Michael E. Steffey, Matthew B. Soellner

39) Hydrocarbon Stapled Peptides as Modulators of Biological Function (ACS Chemical Biology) Tuesday March 31st 2015
Philipp M. Cromm, Jochen Spiegel, Tom N. Grossmann

40) A New Class of Orthosteric uPAR (ACS Chemical Biology) Tuesday March 31st 2015
Degang Liu, Donghui Zhou, Bo Wang, William Eric Knabe, Samy O. Meroueh

41) Discovery of Novel Pneumococcal Surface Antigen A (PsaA) Inhibitors Using a Fragment-based Drug Design Approach (ACS Chemical Biology) Monday March 30th 2015
Megha Bajaj, Sreeman K. Mamidyala, Johannes Zuegg, Stephanie L. Begg, Miranda P. Ween, Zhenyao Luo, Johnny X. Huang, Alastair G. McEwan, Bostjan Kobe, James C. Paton, Christopher A. McDevitt, Matthew A. Cooper

42) PKA-Type I Selective Constrained Peptide Disruptors of AKAP Complexes (ACS Chemical Biology) Wednesday March 25th 2015
Yuxiao Wang, Tienhuei G. Ho, Eugen Franz, Jennifer S. Hermann, F. Donelson Smith, Heidi Hehnly, Jessica L. Esseltine, Laura E. Hanold, Mandi M. Murph, Daniela Bertinetti, John D. Scott, Friedrich W. Herberg, Eileen J. Kennedy

43) Observing Lysozyme (ACS Chemical Biology) Friday March 20th 2015
Maxim V. Akhterov, Yongki Choi, Tivoli J. Olsen, Patrick C. Sims, Mariam Iftikhar, O. Tolga Gul, Brad L. Corso, Gregory A. Weiss, Philip G. Collins

44) A Small Molecule That Inhibits OGT Activity in Cells (ACS Chemical Biology) Wednesday March 18th 2015
Rodrigo F. Ortiz-Meoz, Jiaoyang Jiang, Michael B. Lazarus, Marina Orman, John Janetzko, Chenguang Fan, Damien Y. Duveau, Zhi-Wei Tan, Craig J. Thomas, Suzanne Walker

45) Constructing de Novo H2O2 Signaling via Induced Protein Proximity (ACS Chemical Biology) Wednesday March 18th 2015
Guihua Zeng, Roushu Zhang, Weimin Xuan, Wei Wang, Fu-Sen Liang

46) Optochemical Dissection of T-box Gene-Dependent Medial Floor Plate Development (ACS Chemical Biology) Tuesday March 17th 2015
Alexander Y. Payumo, Whitney J. Walker, Lindsey E. McQuade, Sayumi Yamazoe, James K. Chen

47) Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction (ACS Chemical Biology) Tuesday March 17th 2015
Xiaoqing Wu, Lan Lan, David Michael Wilson, Rebecca T. Marquez, Wei-chung Tsao, Philip Gao, Anuradha Roy, Benjamin Andrew Turner, Peter McDonald, Jon A Tunge, Steven A Rogers, Dan A. Dixon, Jeffrey Aube

48) Chemoenzymatically Prepared Heparan Sulfate Containing Rare 2-O-Sulfonated Glucuronic Acid Residues (ACS Chemical Biology) Tuesday March 17th 2015
Rio S. Boothello, Aurijit Sarkar, Vy My Tran, Thao Kim Nu Nguyen, Nehru Viji Sankaranarayanan, Akul Y. Mehta, AlHumaidi Alabbas, Spencer Brown, Alessandro Rossi, April C. Joice, Caitlin P. Mencio, Maritza V. Quintero, Balagurunathan Kuberan, Umesh R. Desai

49) Inhibitor Recognition Specificity of MERS-CoV Papain-like Protease May Differ from That of SARS-CoV (ACS Chemical Biology) Monday March 16th 2015
Hyun Lee, Hao Lei, Bernard D. Santarsiero, Joseph L. Gatuz, Shuyi Cao, Amy J. Rice, Kavankumar Patel, Michael Z. Szypulinski, Isabel Ojeda, Arun K. Ghosh, Michael E. Johnson

50) Diazirine Photocrosslinking Recruits Activated FTO Demethylase Complexes for Specific N6-methyladenosine Recognition (ACS Chemical Biology) Monday March 16th 2015
Hyun Seok Jeong, Gosuke Hayashi, Akimitsu Okamoto

51) Starter Unit Flexibility for Engineered Product Synthesis by the Nonreducing Polyketide Synthase PksA (ACS Chemical Biology) Tuesday March 10th 2015
Callie R. Huitt-Roehl, Eric A. Hill, Martina M. Adams, Anna L. Vagstad, Jesse W. Li, Craig A. Townsend

52) Michael-Type Cyclizations in Lantibiotic Biosynthesis Are Reversible (ACS Chemical Biology) Tuesday March 10th 2015
Xiao Yang, Wilfred A. van der Donk

53) Molecular Engineering of Nonmetallic Biosensors for CEST MRI (ACS Chemical Biology) Monday March 9th 2015
Amnon Bar-Shir, Jeff W. M. Bulte, Assaf A. Gilad

54) Solvatochromic Nile Red Probes with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells (ACS Chemical Biology) Friday March 6th 2015
Re

55) siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes (ACS Chemical Biology) Monday March 2nd 2015
Shigeo Matsuda, Kristofer Keiser, Jayaprakash K. Nair, Klaus Charisse, Rajar M. Manoharan, Philip Kretschmer, Chang G. Peng, Alexander V. Kel

56) N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus (ACS Chemical Biology) Friday February 27th 2015
Wenxia Fang, David A. Robinson, Olawale G. Raimi, David E. Blair, Justin R. Harrison, Deborah E. A. Lockhart, Leah S. Torrie, Gian Filippo Ruda, Paul G. Wyatt, Ian H. Gilbert, Daan M. F. van Aalten

57) Enantiomers of 3-Methylspermidine Selectively Modulate Deoxyhypusine Synthesis and Reveal Important Determinants for Spermidine Transport (ACS Chemical Biology) Friday February 27th 2015
Mervi T. Hyvo

58) Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases. (ACS Chemical Biology) Thursday February 26th 2015
Steffen M. Bernard, David L. Akey, Ashootosh Tripathi, Sung Ryeol Park, Jamie R. Konwerski, Yojiro Anzai, Shengying Li, Fumio Kato, David H. Sherman, Janet L. Smith

59) Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence Reporter (ACS Chemical Biology) Thursday February 26th 2015
Samuel A. Hasson, Adam I. Fogel, Chunxin Wang, Ryan MacArthur, Rajarshi Guha, Sabrina Heman-Ackah, Scott Martin, Richard J. Youle, James Inglese

60) Trapping of Intermediates with Substrate Analog HBOCoA in the Polymerizations Catalyzed by Class III Polyhydroxybutyrate (PHB) Synthase from Allochromatium Vinosum (ACS Chemical Biology) Wednesday February 25th 2015
Chao Chen, Ruikai Cao, Ruben Shrestha, Christina Ward, Benjamin B. Katz, Christopher J. Fischer, John M. Tomich, Ping Li

61) A Meier-Gorlin Syndrome Mutation Impairs the ORC1-Nucleosome Association (ACS Chemical Biology) Tuesday February 24th 2015
Wei Zhang, Saumya Sankaran, Or Gozani, Jikui Song

62) Illuminating the Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance for the FGFR1 Gatekeeper Mutation: The Achilles (ACS Chemical Biology) Tuesday February 24th 2015
Christal D. Sohl, Molly R. Ryan, BeiBei Luo, Kathleen M. Frey, Karen S. Anderson

63) Positional Impact of Fluorescently Modified G-Tetrads within Polymorphic Human Telomeric G-Quadruplex Structures (ACS Chemical Biology) Tuesday February 24th 2015
Michael Sproviero, Kaila L. Fadock, Aaron A. Witham, Richard A. Manderville

64) Synthesis and Microarray-Assisted Binding Studies of Core Xylose and Fucose Containing N-Glycans (ACS Chemical Biology) Monday February 23rd 2015
Katarzyna Brzezicka, Begon

65) Glycosaminoglycanomics of Cultured Cells Using a Rapid and Sensitive LC-MS/MS Approach (ACS Chemical Biology) Monday February 23rd 2015
Guoyun Li, Lingyun Li, Fang Tian, Linxia Zhang, Changhu Xue, Robert J. Linhardt

66) Rapid Synthesis, RNA Binding, and Antibacterial Screening of a Peptidic-Aminosugar (PA) Library (ACS Chemical Biology) Monday February 23rd 2015
Liuwei Jiang, Derrick Watkins, Yi Jin, Changjun Gong, Ada King, Arren Z. Washington, Keith D. Green, Sylvie Garneau-Tsodikova, Adegboyega K. Oyelere, Dev P. Arya

67) HIV Protease Inhibitors Block Streptolysin S Production (ACS Chemical Biology) Friday February 20th 2015
Tucker Maxson, Caitlin D. Deane, Evelyn M. Molloy, Courtney L. Cox, Andrew L. Markley, Shaun W. Lee, Douglas A. Mitchell

68) Indole-based Cyanine as a Nuclear RNA-Selective Two-Photon Fluorescent Probe for Live Cell Imaging (ACS Chemical Biology) Thursday February 19th 2015
Lei Guo, Miu Shan Chan, Di Xu, Dick Yan Tam, Fre

69) Mechanism of Scrapie Prion Precipitation with Phosphotungstate Anions (ACS Chemical Biology) Thursday February 19th 2015
Dana J. Levine, Jan Sto

70) Human Phospholipase D Activity Transiently Regulates Pyrimidine Biosynthesis in Malignant Gliomas (ACS Chemical Biology) Tuesday February 17th 2015
Thomas P. Mathews, Salisha Hill, Kristie L. Rose, Pavlina T. Ivanova, Craig W. Lindsley, H. Alex Brown

71) Swapped-Domain Constructs of the Glycoprotein-41 Ectodomain Are Potent Inhibitors of HIV Infection (ACS Chemical Biology) Tuesday February 17th 2015
Shidong Chu, Hardeep Kaur, Ariana Nemati, Joseph D. Walsh, Vivian Partida, Shao-Qing Zhang, Miriam Gochin

72) Rapid, Specific, No-wash, Far-red Fluorogen Activation in Subcellular Compartments by Targeted Fluorogen Activating Proteins (ACS Chemical Biology) Monday February 16th 2015
Cheryl A. Telmer, Richa Verma, Haibing Teng, Susan Andreko, Leann Law, Marcel P. Bruchez

73) Biophysical and Biological Characterization of Hairpin and Molecular Beacon RNase H Active Antisense Oligonucleotides (ACS Chemical Biology) Friday February 13th 2015
Michael E.

74) Insights into Methyltransferase Specificity and Bioactivity of Derivatives of the Antibiotic Plantazolicin (ACS Chemical Biology) Wednesday February 11th 2015
Yue Hao, Patricia M. Blair, Abhishek Sharma, Douglas A. Mitchell, Satish K. Nair

75) Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines (ACS Chemical Biology) Monday February 9th 2015
Da Duan, Allison K. Doak, Lyudmila Nedyalkova, Brian K. Shoichet

76) Visualizing Cell Proximity with Genetically Encoded Bioluminescent Reporters (ACS Chemical Biology) Monday February 9th 2015
Krysten A. Jones, David J. Li, Elliot Hui, Mark A. Sellmyer, Jennifer A. Prescher

77) Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain (ACS Chemical Biology) Thursday February 5th 2015
E. Railey White, Luxin Sun, Zhong Ma, Jason M. Beckta, Brittany A. Danzig, David E. Hacker, Melissa Huie, David C. Williams, Ross A. Edwards, Kristoffer Valerie, J. N. Mark Glover, Matthew C. T. Hartman

78) Synergistic Binding of the Leader and Core Peptides by the Lantibiotic Synthetase HalM2 (ACS Chemical Biology) Wednesday February 4th 2015
Gabrielle N. Thibodeaux, Amanda L. McClerren, Yunli Ma, Marc R. Gancayco, Wilfred A. van der Donk

79) Identification of Potent Phosphodiesterase Inhibitors that Demonstrate Cyclic Nucleotide-Dependent Functions in Apicomplexan Parasites (ACS Chemical Biology) Wednesday February 4th 2015
Brittany L. Howard, Katherine L. Harvey, Rebecca J. Stewart, Mauro F. Azevedo, Brendan S. Crabb, Ian G. Jennings, Paul R. Sanders, David T. Manallack, Philip E. Thompson, Christopher J. Tonkin, Paul R. Gilson

80) Isofunctional Enzymes PAD1 and UbiX Catalyze Formation of a Novel Cofactor Required by Ferulic Acid Decarboxylase and 4-Hydroxy-3-polyprenylbenzoic Acid Decarboxylase (ACS Chemical Biology) Tuesday February 3rd 2015
Fengming Lin, Kyle L. Ferguson, David R. Boyer, Xiaoxia Nina Lin, E. Neil G. Marsh

81) Structural Basis of New Allosteric Inhibition in Kinesin Spindle Protein Eg5 (ACS Chemical Biology) Tuesday February 3rd 2015
Hideshi Yokoyama, Jun-ichi Sawada, Shiori Katoh, Kenji Matsuno, Naohisa Ogo, Yoshinobu Ishikawa, Hiroshi Hashimoto, Satoshi Fujii, Akira Asai

82) Structural Basis of a Temporin 1b Analogue Antimicrobial Activity against Gram Negative Bacteria Determined by CD and NMR Techniques in Cellular Environment (ACS Chemical Biology) Friday January 30th 2015
Gaetano Malgieri, Concetta Avitabile, Maddalena Palmieri, Luca Domenico D

83) Structure-Guided Design of a High Affinity Inhibitor to Human CtBP (ACS Chemical Biology) Friday January 30th 2015
Brendan J. Hilbert, Benjamin L. Morris, Keith C. Ellis, Janet L. Paulsen, Celia A. Schiffer, Steven R. Grossman, William E. Royer

84) Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites (ACS Chemical Biology) Friday January 30th 2015
I. J. Frame, Roman Deniskin, Alison Rinderspacher, Francine Katz, Shi-Xian Deng, Robyn D. Moir, Sophie H. Adjalley, Olivia Coburn-Flynn, David A. Fidock, Ian M. Willis, Donald W. Landry, Myles H. Akabas

85) Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes That Promote Autophagic Tau Clearance (ACS Chemical Biology) Friday January 30th 2015
Mackenzie D. Martin, Laurent Calcul, Courtney Smith, Umesh K. Jinwal, Sarah N. Fontaine, April Darling, Kent Seeley, Lukasz Wojtas, Malathi Narayan, Jason E. Gestwicki, Garry R. Smith, Allen B. Reitz, Bill J. Baker, Chad A. Dickey

86) Genetically Enhanced Lysozyme Evades a Pathogen Derived Inhibitory Protein (ACS Chemical Biology) Friday January 30th 2015
Sarah M. Dostal, Yongliang Fang, Jonathan C. Guerrette, Thomas C. Scanlon, Karl E. Griswold

87) Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes (ACS Chemical Biology) Thursday January 29th 2015
Erik C. Hett, Hua Xu, Kieran F. Geoghegan, Ariamala Gopalsamy, Robert E. Kyne, Carol A. Menard, Arjun Narayanan, Mihir D. Parikh, Shenping Liu, Lee Roberts, Ralph P. Robinson, Michael A. Tones, Lyn H. Jones

88) C5-Epimerase and 2-O-Sulfotransferase Associate in Vitro to Generate Contiguous Epimerized and 2-O-Sulfated Heparan Sulfate Domains (ACS Chemical Biology) Wednesday January 28th 2015
Aure

89) Computational Design and Experimental Characterization of Peptides Intended for pH-Dependent Membrane Insertion and Pore Formation (ACS Chemical Biology) Wednesday January 28th 2015
Yao Zhang, Rene

90) Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1 (ACS Chemical Biology) Wednesday January 28th 2015
Michael T. Perfetti, Brandi M. Baughman, Bradley M. Dickson, Yunxiang Mu, Gaofeng Cui, Pavel Mader, Aiping Dong, Jacqueline L. Norris, Scott B. Rothbart, Brian D. Strahl, Peter J. Brown, William P. Janzen, Cheryl H. Arrowsmith, Georges Mer, Kevin M. McBride, Lindsey I. James, Stephen V. Frye

91) Genetic Targeting of a Small Fluorescent Zinc Indicator to Cell Surface for Monitoring Zinc Secretion (ACS Chemical Biology) Tuesday January 27th 2015
Daliang Li, Lin Liu, Wen-Hong Li

92) Small Molecule Inhibitors of Disulfide Bond Formation by the Bacterial DsbA (ACS Chemical Biology) Tuesday January 27th 2015
Maria A. Halili, Prabhakar Bachu, Fredrik Lindahl, Che

93) Stereospecific Phosphorylation by the Central Mitotic Kinase Cdk1-Cyclin B (ACS Chemical Biology) Monday January 26th 2015
Felicia A. Etzkorn, Song Zhao

94) Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design (ACS Chemical Biology) Monday January 26th 2015
Daniel J. Slade, Pengfei Fang, Christina J. Dreyton, Ying Zhang, Jakob Furhmann, Don Rempel, Benjamin D. Bax, Scott A. Coonrod, Huw D. Lewis, Min Guo, Michael L. Gross, Paul R. Thompson

95) Family of Class I Lantibiotics from Actinomycetes and Improvement of Their Antibacterial Activities (ACS Chemical Biology) Friday January 23rd 2015
Sonia I. Maffioli, Paolo Monciardini, Bruno Catacchio, Carlo Mazzetti, Daniela Mu

96) The Elastase-PK101 Structure: Mechanism of an Ultrasensitive Activity-based Probe Revealed (ACS Chemical Biology) Thursday January 22nd 2015
Bernhard C. Lechtenberg, Paulina Kasperkiewicz, Howard Robinson, Marcin Drag, Stefan J. Riedl

97) Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water (ACS Chemical Biology) Thursday January 22nd 2015
Fumito Saito, Hidetoshi Noda, Jeffrey W. Bode

98) Structural and Functional Analysis of the Loading Acyltransferase from Avermectin Modular Polyketide Synthase (ACS Chemical Biology) Thursday January 22nd 2015
Fen Wang, Yanjie Wang, Junjie Ji, Zhan Zhou, Jingkai Yu, Hua Zhu, Zhiguo Su, Lixin Zhang, Jianting Zheng

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