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1) pH-Dependent DNA Distortion and Repression of Gene Expression by Pectobacterium atrosepticum PecS (ACS Chemical Biology) Friday May 27th 2016
Dinesh K. Deochand, Jacob K. Meariman, Anne Grove

2) Advances in Enzymatic Glycoside Synthesis (ACS Chemical Biology) Thursday May 26th 2016
Phillip M. Danby, Stephen G. Withers

3) Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules (ACS Chemical Biology) Thursday May 26th 2016
Mackenzie D. Martin, Jeremy D. Baker, Amirthaa Suntharalingam, Bryce A. Nordhues, Lindsey B. Shelton, Dali Zheng, Jonathan J. Sabbagh, Timothy A.J. Haystead, Jason E. Gestwicki, Chad A. Dickey

4) Perspectives on Anti-Glycan Antibodies Gleaned from Development of a Community Resource Database (ACS Chemical Biology) Wednesday May 25th 2016
Eric Sterner, Natalie Flanagan, Jeffrey C. Gildersleeve

5) Profiling Esterases in Mycobacterium tuberculosis Using Far-Red Fluorogenic Substrates (ACS Chemical Biology) Monday May 23rd 2016
Katie R. Tallman, Samantha R. Levine, Kimberly E. Beatty

6) Conjugation Strategy Strongly Impacts the Conformational Stability of a PEG-Protein Conjugate (ACS Chemical Biology) Saturday May 21st 2016
Paul B. Lawrence, Wendy M. Billings, McKenzie B. Miller, Brijesh K. Pandey, Andrew R. Stephens, Minnie I. Langlois, Joshua L. Price

7) Monitoring Nitric Oxide in Subcellular Compartments by Hybrid Probe Based on Rhodamine Spirolactam and SNAP-tag (ACS Chemical Biology) Friday May 20th 2016
Chao Wang, Xinbo Song, Zhuo Han, Xiaoyu Li, Yongping Xu, Yi Xiao

8) The Hidden Conformation of Lewis x, a Human Histo-Blood Group Antigen, Is a Determinant for Recognition by Pathogen Lectins (ACS Chemical Biology) Friday May 20th 2016
Je

9) Cladribine and Fludarabine Nucleotides Induce Distinct Hexamers Defining a Common Mode of Reversible RNR Inhibition (ACS Chemical Biology) Friday May 20th 2016
Somsinee Wisitpitthaya, Yi Zhao, Marcus J. C. Long, Minxing Li, Elaine A. Fletcher, William A. Blessing, Robert S. Weiss, Yimon Aye

10) Characterization of Three Tailoring Enzymes in Dutomycin Biosynthesis and Generation of a Potent Antibacterial Analogue (ACS Chemical Biology) Thursday May 19th 2016
Lei Sun, Siyuan Wang, Shuwei Zhang, Lei Shao, Qian Zhang, Chad Skidmore, Cheng-Wei Tom Chang, Dayu Yu, Jixun Zhan

11) Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics (ACS Chemical Biology) Thursday May 19th 2016
Ge

12) Structure (ACS Chemical Biology) Wednesday May 18th 2016
Tian Yang, Yftah Tal-Gan, Alexandra E. Paharik, Alexander R. Horswill, Helen E. Blackwell

13) A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes (ACS Chemical Biology) Tuesday May 17th 2016
Wesley Wei Wang, Yu Zeng, Bo Wu, Alexander Deiters, Wenshe R. Liu

14) Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure (ACS Chemical Biology) Tuesday May 17th 2016
Tengfeng Ni, Fei Ye, Xing Liu, Jie Zhang, Hongchuan Liu, Jiahui Li, Yingyi Zhang, Yingqiang Sun, Meining Wang, Cheng Luo, Hualiang Jiang, Lefu Lan, Jianhua Gan, Ao Zhang, Hu Zhou, Cai-Guang Yang

15) Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects (ACS Chemical Biology) Friday May 13th 2016
Florence F. Wagner, Joshua A. Bishop, Jennifer P. Gale, Xi Shi, Michelle Walk, Joshua Ketterman, Debasis Patnaik, Doug Barker, Deepika Walpita, Arthur J. Campbell, Shannon Nguyen, Michael Lewis, Linda Ross, Michel Wei

16) Sequence-Specific Biosensing of DNA Target through Relay PCR with Small-Molecule Fluorophore (ACS Chemical Biology) Thursday May 12th 2016
Afshan Yasmeen, Feng Du, Yongyun Zhao, Juan Dong, Haodong Chen, Xin Huang, Xin Cui, Zhuo Tang

17) Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector (ACS Chemical Biology) Thursday May 12th 2016
Willy Jablonka, Van Pham, Glenn Nardone, Apostolos Gittis, Li

18) Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK (ACS Chemical Biology) Wednesday May 11th 2016
Danielle L. Schmitt, Yun-ju Cheng, Junyong Park, Songon An

19) Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening (ACS Chemical Biology) Wednesday May 11th 2016
Peter Man-Un Ung, Wenxin Song, Lili Cheng, Xinbin Zhao, Hailin Hu, Ligong Chen, Avner Schlessinger

20) Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2 (ACS Chemical Biology) Wednesday May 11th 2016
Christophe Marchand, Monica Abdelmalak, Jayakanth Kankanala, Shar-Yin Huang, Evgeny Kiselev, Katherine Fesen, Kayo Kurahashi, Hiroyuki Sasanuma, Shunichi Takeda, Hideki Aihara, Zhengqiang Wang, Yves Pommier

21) Discovery of a novel NEDD8 Activating Enzyme Inhibitor with Piperidin-4-amine Scaffold by Structure-Based Virtual Screening (ACS Chemical Biology) Friday May 6th 2016
Peng Lu, Xiaoxin Liu, Xinrui Yuan, Minfang He, Yubin Wang, Qi Zhang, Ping-kai Ouyang

22) Bacterial (ACS Chemical Biology) Friday May 6th 2016
Ratana Charoenwattanasatien, Salila Pengthaisong, Imogen Breen, Risa Mutoh, Sompong Sansenya, Yanling Hua, Anupong Tankrathok, Liang Wu, Chomphunuch Songsiriritthigul, Hideaki Tanaka, Spencer J. Williams, Gideon J. Davies, Genji Kurisu, James R. Ketudat Cairns

23) Hepatitis C Virus Selectively Alters the Intracellular Localization of Desmosterol (ACS Chemical Biology) Friday May 6th 2016
Valerie A. Villareal, Dan Fu, Deirdre A. Costello, Xiaoliang Sunney Xie, Priscilla L. Yang

24) ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse (ACS Chemical Biology) Thursday May 5th 2016
Larry S. Barak, Yushi Bai, Sean Peterson, Tama Evron, Nikhil M. Urs, Satyamaheshwar Peddibhotla, Michael P. Hedrick, Paul Hershberger, Patrick R. Maloney, Thomas D.Y. Chung, Ramona M. Rodriguiz, William C. Wetsel, James B. Thomas, Glen R. Hanson, Anthony B. Pinkerton, Marc G. Caron

25) Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators (ACS Chemical Biology) Wednesday May 4th 2016
Karen J. Gregory, Ranganadh Velagaleti, David M. Thal, Ryan M. Brady, Arthur Christopoulos, P. Jeffrey Conn, David J. Lapinsky

26) Fusion of Ferredoxin and Cytochrome P450 Enables Direct Light-Driven Biosynthesis (ACS Chemical Biology) Wednesday May 4th 2016
Silas Busck Mellor, Agnieszka Zygadlo Nielsen, Meike Burow, Mohammed Saddik Motawia, Dainius Jakubauskas, Birger Lindberg M

27) Elastase-like Activity Is Dominant to Chymotrypsin-like Activity in 20S Proteasome (ACS Chemical Biology) Monday May 2nd 2016
Dennis Bensinger, Theresa Neumann, Christoph Scholz, Constantin Voss, Sabine Knorr, Ulrike Kuckelkorn, Kay Hamacher, Peter-Michael Kloetzel, Boris Schmidt

28) Delivery of Non-Native Cargo into Mammalian Cells Using Anthrax Lethal Toxin (ACS Chemical Biology) Monday May 2nd 2016
Amy E. Rabideau, Bradley Lether Pentelute

29) Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon (ACS Chemical Biology) Friday April 29th 2016
Wentao Chen, Leopold Kong, Stephen Connelly, Julia M. Dendle, Yu Liu, Ian A. Wilson, Evan T. Powers, Jeffery W. Kelly

30) Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1 (ACS Chemical Biology) Friday April 29th 2016
Ian Mitchelle S. de Vera, Pankaj K. Giri, Paola Munoz-Tello, Richard Brust, Jakob Fuhrmann, Edna Matta-Camacho, Jinsai Shang, Sean Campbell, Henry D. Wilson, Juan Granados, William J. Gardner, Trevor P. Creamer, Laura. A. Solt, Douglas J. Kojetin

31) Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile (ACS Chemical Biology) Friday April 29th 2016
Zarko V. Boskovic, Melissa M. Kemp, Allyson M. Freedy, Vasanthi S. Viswanathan, Marius S. Pop, Jason H. Fuller, Nicole M. Martinez, Samuel O. Figueroa Lazu

32) Cell Permeable Ratiometric Fluorescent Sensors for Imaging Phosphoinositides (ACS Chemical Biology) Friday April 29th 2016
Samsuzzoha Mondal, Ananya Rakshit, Suranjana Pal, Ankona Datta

33) Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds (ACS Chemical Biology) Friday April 29th 2016
Michael Zender, Florian Witzgall, Steffen L. Drees, Elisabeth Weidel, Christine K. Maurer, Susanne Fetzner, Wulf Blankenfeldt, Martin Empting, Rolf W. Hartmann

34) Pharmacological Chaperones: Design and Development of New Therapeutic Strategies for the Treatment of Conformational Diseases (ACS Chemical Biology) Friday April 29th 2016
Marino Convertino, Jhuma Das, Nikolay V. Dokholyan

35) Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells (ACS Chemical Biology) Friday April 29th 2016
Naowras Al-Obaidi, Timothy J. Mitchison, Craig M. Crews, Thomas U. Mayer

36) Synthesis and Characterization of a Promising Novel FFAR1/GPR40 Targeting Fluorescent Probe for (ACS Chemical Biology) Tuesday April 26th 2016
Romain Bertrand, Andrea Wolf, Yuri Ivashchenko, Matthias Lo

37) Production of Sactipeptides in Escherichia coli: Probing the Substrate Promiscuity of Subtilosin A Biosynthesis (ACS Chemical Biology) Monday April 25th 2016
Paul M. Himes, Scott E. Allen, Sungwon Hwang, Albert A. Bowers

38) Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1 (ACS Chemical Biology) Friday April 22nd 2016
Zhemin Zhang, Jiemin Shen, Ye Yang, Jing Li, Weiguo Cao, Wei Xie

39) Discovery of a Highly Selective STK16 Kinase Inhibitor (ACS Chemical Biology) Friday April 22nd 2016
Feiyang Liu, Jinhua Wang, Xingxing Yang, Binhua Li, Hong Wu, Shuang Qi, Cheng Chen, Xiaochuan Liu, Kailin Yu, Wenchao Wang, Zheng Zhao, Aoli Wang, Yongfei Chen, Li Wang, Nathanael S. Gray, Jing Liu, Xin Zhang, Qingsong Liu

40) Cell-specific Profiling of Nascent Proteomes Using Orthogonal Enzyme-mediated Puromycin Incorporation (ACS Chemical Biology) Thursday April 21st 2016
Ruth M. Barrett, Hui-wen Liu, Haihong Jin, Richard H. Goodman, Michael S. Cohen

41) Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs (ACS Chemical Biology) Wednesday April 20th 2016
Matthew D. Disney, Audrey M. Winkelsas, Sai Pradeep Velagapudi, Mark Southern, Mohammad Fallahi, Jessica L. Childs-Disney

42) Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9 (ACS Chemical Biology) Tuesday April 19th 2016
Pelin Ayaz, Dorothee Andres, Dennis A. Kwiatkowski, Carl-Christian Kolbe, Philip Lienau, Gerhard Siemeister, Ulrich Lu

43) Altering the Specificity of the Antibody Response to HIV gp120 with a Glycoconjugate Antigen (ACS Chemical Biology) Monday April 18th 2016
Chang-Cheng Liu, Canjia Zhai, Xiu-Jing Zheng, Xin-Shan Ye

44) The Chemical Ecology of Predatory Soil Bacteria (ACS Chemical Biology) Friday April 15th 2016
Brandon L. Findlay

45) Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa (ACS Chemical Biology) Monday April 11th 2016
Mijoon Lee, Teresa Domi

46) Global Isotope Metabolomics Reveals Adaptive Strategies for Nitrogen Assimilation (ACS Chemical Biology) Friday April 8th 2016
Michael E. Kurczy, Erica M. Forsberg, Michael P. Thorgersen, Farris L. Poole, H. Paul Benton, Julijana Ivanisevic, Minerva L. Tran, Judy D. Wall, Dwayne A. Elias, Michael W. W. Adams, Gary Siuzdak

47) Exploring Peptide Ligase Orthologs in Actinobacteria (ACS Chemical Biology) Friday April 8th 2016
Yasushi Ogasawara, Junpei Kawata, Motoyoshi Noike, Yasuharu Satoh, Kazuo Furihata, Tohru Dairi

48) Transition State Structure and Inhibition of Rv0091, a 5 (ACS Chemical Biology) Friday April 8th 2016
Hilda A. Namanja-Magliano, Christopher F. Stratton, Vern L. Schramm

49) Identification of a Novel Mycobacterial Arabinosyltransferase Activity Which Adds an Arabinosyl Residue to (ACS Chemical Biology) Friday April 8th 2016
Shiva kumar Angala, Michael R. McNeil, Lu Zou, Avraham Liav, Junfeng Zhang, Todd L. Lowary, Mary Jackson

50) Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case Study (ACS Chemical Biology) Friday April 8th 2016
Johannes Schiebel, Nedyalka Radeva, Stefan G. Krimmer, Xiaojie Wang, Martin Stieler, Frederik R. Ehrmann, Kan Fu, Alexander Metz, Franziska U. Huschmann, Manfred S. Weiss, Uwe Mueller, Andreas Heine, Gerhard Klebe

51) Synchronous Bioimaging of Intracellular pH and Chloride Based on LSS Fluorescent Protein (ACS Chemical Biology) Thursday April 7th 2016
Jose M. Paredes, Aurora I. Idilli, Letizia Mariotti, Gabriele Losi, Lyaysan R. Arslanbaeva, Sebastian Sulis Sato, Pietro Artoni, Joanna Szczurkowska, Laura Cancedda, Gian Michele Ratto, Giorgio Carmignoto, Daniele Arosio

52) Benzothiazole Sulfinate: a Water-Soluble and Slow-Releasing Sulfur Dioxide Donor (ACS Chemical Biology) Thursday April 7th 2016
Jacob J. Day, Zhenhua Yang, Wei Chen, Armando Pacheco, Ming Xian

53) An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures (ACS Chemical Biology) Thursday April 7th 2016
Paul J. Sapienza, Li Li, Tishan Williams, Andrew L. Lee, Charles W. Carter

54) Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF- (ACS Chemical Biology) Thursday April 7th 2016
Nicholas B. Struntz, Daniel A. Harki

55) Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis (ACS Chemical Biology) Thursday April 7th 2016
Melisa J. Willby, Keith D. Green, Chathurada S. Gajadeera, Caixia Hou, Oleg V. Tsodikov, James E. Posey, Sylvie Garneau-Tsodikova

56) Traceless Production of Cyclic Peptide Libraries in E. coli (ACS Chemical Biology) Wednesday April 6th 2016
Jaime E. Townend, Ali Tavassoli

57) Chondro-Protective and Antiarthritic Effects of Sulfonamido-Based Gallate (ACS Chemical Biology) Tuesday April 5th 2016
Zhenhui Lu, Huayu Wu, Xiao Lin, Buming Liu, Cuiwu Lin, Li Zheng, Jinmin Zhao

58) Site-Specific Radiofluorination of Biomolecules with 8-[18F]-Fluorooctanoic Acid Catalyzed by Lipoic Acid Ligase (ACS Chemical Biology) Thursday March 31st 2016
Christopher R. Drake, Natalia Sevillano, Charles Truillet, Charles S. Craik, Henry F. VanBrocklin, Michael J. Evans

59) Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib (ACS Chemical Biology) Thursday March 31st 2016
Sebastian Mathea, Kamal R. Abdul Azeez, Eidarus Salah, Cynthia Tallant, Finn Wolfreys, Rebecca Konietzny, Roman Fischer, Hua Jane Lou, Paul E. Brennan, Gisela Schnapp, Alexander Pautsch, Benedikt M. Kessler, Benjamin E. Turk, Stefan Knapp

60) Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition (ACS Chemical Biology) Thursday March 31st 2016
Maureen E. Hill, Derek J. MacPherson, Peng Wu, Olivier Julien, James A. Wells, Jeanne A. Hardy

61) Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle (ACS Chemical Biology) Wednesday March 30th 2016
Alvaro J. Amor, Karl R. Schmitz, Jason K. Sello, Tania A. Baker, Robert T. Sauer

62) Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly (ACS Chemical Biology) Tuesday March 29th 2016
Wei-Guang Seetoh, Daniel Shiu-Hin Chan, Dijana Matak-Vinkovic

63) Nicotinamide Cofactors Suppress Active-Site Labeling of Aldehyde Dehydrogenases (ACS Chemical Biology) Friday March 25th 2016
Naim Stiti, Balakumaran Chandrasekar, Laura Strubl, Shabaz Mohammed, Dorothea Bartels, Renier A. L. van der Hoorn

64) Designing an Antibody-Based Chaperoning System through Programming the Binding and Release of the Folding Intermediate (ACS Chemical Biology) Friday March 25th 2016
Tingting Liu, Caixian Sun, Cong Li, Jinhyuk Lee, Yong-Doo Park, Yixin Zhang, Sen Li

65) Directed Evolution of a Cyclized Peptoid (ACS Chemical Biology) Thursday March 24th 2016
Takashi Kawakami, Koji Ogawa, Tomohisa Hatta, Naoki Goshima, Tohru Natsume

66) Bacterial Riboswitches and Ribozymes Potently Activate the Human Innate Immune Sensor PKR (ACS Chemical Biology) Thursday March 24th 2016
Chelsea M. Hull, Ananya Anmangandla, Philip C. Bevilacqua

67) Thymidylate Limitation Potentiates Cephalosporin Activity toward Enterococci via an Exopolysaccharide-Based Mechanism (ACS Chemical Biology) Wednesday March 23rd 2016
Jessica S. Hoff, Christopher J. Kristich

68) Mixing Up the Pieces of the Desferrioxamine B Jigsaw Defines the Biosynthetic Sequence Catalyzed by DesD (ACS Chemical Biology) Wednesday March 23rd 2016
Thomas J. Telfer, Michael P. Gotsbacher, Cho Zin Soe, Rachel Codd

69) Chemically Modifying Viruses for Diverse Applications (ACS Chemical Biology) Monday March 21st 2016
Kritika Mohan, Gregory A. Weiss

70) Why Nature Chose Selenium (ACS Chemical Biology) Monday March 21st 2016
Hans J. Reich, Robert J. Hondal

71) Targeting Tumor Cells by Natural Anti-Carbohydrate Antibodies Using Rhamnose-Functionalized Liposomes (ACS Chemical Biology) Friday March 18th 2016
Xuexia Li, Xiongjian Rao, Li Cai, Xuling Liu, Huixia Wang, Weinan Wu, Chenggang Zhu, Min Chen, Peng G. Wang, Wen Yi

72) Reaction of PerR with Molecular Oxygen May Assist H2O2 Sensing in Anaerobes (ACS Chemical Biology) Wednesday March 16th 2016
Ramakrishnan Sethu, Eric Goure

73) Orthogonal Assays Clarify the Oxidative Biochemistry of Taxol P450 CYP725A4 (ACS Chemical Biology) Wednesday March 16th 2016
Bradley Walters Biggs, John Edward Rouck, Amogh Kambalyal, William Arnold, Chin Giaw Lim, Marjan De Mey, Mark O

74) A Small Molecule Screen Exposes mTOR Signaling Pathway Involvement in Radiation-Induced Apoptosis (ACS Chemical Biology) Monday March 14th 2016
Elizabeth R. Sharlow, Stephanie Leimgruber, Ana Lira, Michael J. McConnell, Andre

75) Vectorization of Nucleic Acids for Therapeutic Approach: Tutorial Review (ACS Chemical Biology) Friday March 11th 2016
Frederic Geinguenaud, Erwann Guenin, Yoann Lalatonne, Laurence Motte

76) Phage Selection of Chemically Stabilized (ACS Chemical Biology) Friday March 11th 2016
Philippe Diderich, Davide Bertoldo, Pierre Dessen, Maola M. Khan, Irene Pizzitola, Werner Held, Joerg Huelsken, Christian Heinis

77) Mapping and Exploring the Collagen-I Proteostasis Network (ACS Chemical Biology) Wednesday March 9th 2016
Andrew S. DiChiara, Rebecca J. Taylor, Madeline Y. Wong, Ngoc-Duc Doan, Amanda M. Del Rosario, Matthew D. Shoulders

78) Chemically Induced Cryptic Sesquiterpenoids and Expression of Sesquiterpene Cyclases in Botrytis cinerea Revealed New Sporogenic (+)-4-Epieremophil-9-en-11-ols (ACS Chemical Biology) Tuesday March 8th 2016
Cristina Pinedo, Javier Moraga, Javier Barua, Victoria E. Gonza

79) Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics (ACS Chemical Biology) Tuesday March 8th 2016
Rafael Molina, Neva Besker, Maria Jose Marcaida, Guillermo Montoya, Jesu

80) Transition State Structure of RNA Depurination by Saporin L3 (ACS Chemical Biology) Tuesday March 8th 2016
Hongling Yuan, Christopher F. Stratton, Vern L. Schramm

81) Application of an Integrated GPCR SAR-Modeling Platform To Explain the Activation Selectivity of Human 5-HT2C over 5-HT2B (ACS Chemical Biology) Monday March 7th 2016
Alexander Heifetz, R. Ian Storer, Gordon McMurray, Tim James, Inaki Morao, Matteo Aldeghi, Mike J. Bodkin, Philip C. Biggin

82) Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus (ACS Chemical Biology) Friday March 4th 2016
Brendan F. Dutter, Laura A. Mike, Paul R. Reid, Katherine M. Chong, Susan J. Ramos-Hunter, Eric P. Skaar, Gary A. Sulikowski

83) Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Antiparasitic Drug Targets (ACS Chemical Biology) Friday March 4th 2016
Yunyun Yang, Tzu-Ping Ko, Chun-Chi Chen, Guozhong Huang, Yingying Zheng, Weidong Liu, Iren Wang, Meng-Ru Ho, Shang-Te Danny Hsu, Bing O

84) Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions (ACS Chemical Biology) Friday March 4th 2016
Changjun You, Pengcheng Wang, Stephanie L. Nay, Jianshuang Wang, Xiaoxia Dai, Timothy R. O

85) Structural Analysis of the Tobramycin and Gentamicin Clinical Resistome Reveals Limitations for Next-generation Aminoglycoside Design (ACS Chemical Biology) Friday March 4th 2016
Angelia V. Bassenden, Dmitry Rodionov, Kun Shi, Albert M. Berghuis

86) FRET Characterization of Complex Conformational Changes in a Large 16S Ribosomal RNA Fragment Site-Specifically Labeled Using Unnatural Base Pairs (ACS Chemical Biology) Friday March 4th 2016
Thomas Lavergne, Rajan Lamichhane, Denis A. Malyshev, Zhengtao Li, Lingjun Li, Edit Sperling, James R. Williamson, David P. Millar, Floyd E. Romesberg

87) Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer (ACS Chemical Biology) Thursday March 3rd 2016
Michelle S. Bousquet, Jia Jia Ma, Ranjala Ratnayake, Pamela A. Havre, Jin Yao, Nam H. Dang, Valerie J. Paul, Thomas J. Carney, Long H. Dang, Hendrik Luesch

88) SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context (ACS Chemical Biology) Thursday March 3rd 2016
Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin

89) The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency (ACS Chemical Biology) Wednesday March 2nd 2016
Lei Feng, Venkatasubramanian Dharmarajan, Erik Serrao, Ashley Hoyte, Ross C. Larue, Alison Slaughter, Amit Sharma, Matthew R. Plumb, Jacques J. Kessl, James R. Fuchs, Frederic D. Bushman, Alan N. Engelman, Patrick R. Griffin, Mamuka Kvaratskhelia

90) Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin (ACS Chemical Biology) Tuesday March 1st 2016
Li Zha, Matthew R. Wilson, Carolyn A. Brotherton, Emily P. Balskus

91) Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells (ACS Chemical Biology) Tuesday March 1st 2016
Rachel P. Abrams, William L. Carroll, K. A. Woerpel

92) Recent Advance in Tumor-associated Carbohydrate Antigens (TACAs)-based Antitumor Vaccines (ACS Chemical Biology) Tuesday March 1st 2016
Danyang Feng, Abdul Sami Shaikh, Fengshan Wang

93) Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity (ACS Chemical Biology) Tuesday March 1st 2016
Frank E. Kwarcinski, Kristoffer R. Brandvold, Sameer Phadke, Omar M. Beleh, Taylor K. Johnson, Jennifer L. Meagher, Markus A. Seeliger, Jeanne A. Stuckey, Matthew B. Soellner

94) Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections (ACS Chemical Biology) Tuesday March 1st 2016
Andreas Thomann, Antonio G. G. de Mello Martins, Christian Brengel, Martin Empting, Rolf W. Hartmann

95) Visible Light-Controlled Nitric Oxide Release from Hindered Nitrobenzene Derivatives for Specific Modulation of Mitochondrial Dynamics (ACS Chemical Biology) Monday February 29th 2016
Kai Kitamura, Mitsuyasu Kawaguchi, Naoya Ieda, Naoki Miyata, Hidehiko Nakagawa

96) Analysis of Iterative Screening with Stepwise Compound Selection Based on Novartis In-house HTS Data (ACS Chemical Biology) Friday February 26th 2016
Shardul Paricharak, Adriaan P. IJzerman, Andreas Bender, Florian Nigsch

97) Imaging Pseudomonas aeruginosa Biofilm Extracellular Polymer Scaffolds with Amphiphilic Carbon Dots (ACS Chemical Biology) Friday February 26th 2016
Margarita Ritenberg, Sukhendu Nandi, Sofiya Kolusheva, Rambabu Dandela, Michael M. Meijler, Raz Jelinek

98) Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors (ACS Chemical Biology) Thursday February 25th 2016
Susan Klaeger, Bjoern Gohlke, Jessica Perrin, Vipul Gupta, Stephanie Heinzlmeir, Dominic Helm, Huichao Qiao, Giovanna Bergamini, Hiroshi Handa, Mikhail M Savitski, Marcus Bantscheff, Guillaume Me

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